Streptomyces spinosirectus: LXH13_18535
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Entry
LXH13_18535 CDS
T08958
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sspn
Streptomyces spinosirectus
Pathway
sspn00860
Porphyrin metabolism
sspn01100
Metabolic pathways
sspn01110
Biosynthesis of secondary metabolites
sspn01120
Microbial metabolism in diverse environments
sspn01240
Biosynthesis of cofactors
Module
sspn_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
sspn_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sspn_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sspn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
LXH13_18535
Enzymes [BR:
sspn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
LXH13_18535
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
LXH13_18535
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
UIR18925
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Position
complement(4014877..4016583)
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AA seq
568 aa
AA seq
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MSPTTLPTGLEHGHVTFLGAGPGDPGLLTLRAVEALANADVLVAEHDVLDVVRKHARQGV
AEVHTDGGPSADSHPGTGTPQLAVVDGSSTTAGVPAVRDAAHLVMEAARGGRRVVRAVAG
DPGLDTYAAEEMLACAGAGVPFEVVPGVAAAVGVPAYAGVPLRDAEGADVRFVDARTASD
RCWTEVGASDGTVVVSTTLDSVGAAAGELVSAGRKPDTPMTVTIAGTTTRQRTWTATLGT
IAQTLKQAKVLPSPEGGRPVIAVVGDRSAPAQRDQLSWFESKPLFGWKVLVPRTKEQAAS
LSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFE
EYGLDARAFAGIKVAAVGEQTANALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPID
RVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSS
STVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALADFGLRR
RAAALEAGDAVTRPSERRPGARRRRTTT
NT seq
1707 nt
NT seq
+upstream
nt +downstream
nt
gtgagccccaccacccttcccaccggcctcgaacacgggcacgtcaccttcctcggtgcc
ggacccggggatccgggactgctgactctgcgcgccgtcgaggcgctggcgaacgcggac
gtactggtcgccgagcacgacgtgctcgacgtggtgcgcaagcacgccaggcaaggcgtc
gccgaggtgcacacggacgggggtccttctgcggactcccacccgggcacgggcacacct
cagctggcggttgttgacggatcgtcaacaaccgctggggtccccgcggtacgggatgcc
gcacatcttgtcatggaggccgcgcggggcggcaggcgggtcgtccgtgcggtcgcgggg
gaccctggcctggacacttacgccgcggaggagatgctcgcctgcgccggtgcgggggtg
cccttcgaggtcgtccccggtgtcgccgccgccgtcggtgtgcccgcctacgcgggtgtc
ccgctgcgggacgccgagggcgcggacgtgcggttcgtggacgcccgtaccgcctcggac
cggtgctggacggaggtgggggcctccgacgggaccgtggtcgtgtcgacgacgctcgac
tccgtcggtgcggccgcgggtgagctggtgtcggcgggccgcaagccggacacgccgatg
acggtgaccatcgcgggcaccaccacgcgccagcggacctggacggcgacgctcggcacc
atcgcgcagaccctgaagcaggccaaggtgctgccctcgccggagggcggccgcccggtg
atagccgtggtcggagaccgcagcgcccccgcccagcgcgaccagctgtcgtggttcgag
tccaagccgctgttcggctggaaggtcctcgtgccgcgtacgaaggagcaggcggcgtcg
ctctccgaccagttgcggtcgtacggcgccgtaccgcacgaggtcccgacgatcgccgtc
gaacccccgcgcaccccgcagcagatggagcgcgcggtcaagggcctggtcaccggccgc
tacgagtggatcgccttcacctcggtcaacgccgtcaaggcggtccgggagaagttcgag
gagtacggcctggacgcgcgtgccttcgcgggcatcaaggtcgcggcggtcggcgagcag
accgccaacgcgctgatcgccttcggcgtgaagccggacctggtgccgagcggcgagcag
tcggccgcgggcctgctggaggactggcctccttacgacccggtcttcgacccgatcgac
cgtgtcttcctgccccgcgcggacatcgccacggaaaccctcgtcgccgggctgatcgag
ctgggctgggaggtcgacgacgtcacggcgtaccgcaccgtacgggcgtcgcccccgccg
gccgagacccgcgaggcgatcaagggcggcggcttcgacgccgttctcttcacgtcgtcc
tccaccgtccgcaacctcgtcggcatcgcgggcaagccccacaacgtgaccgtcatcgcg
tgcatcggcccggcaacggcgaagaccgccgaggagcacggcctgcgtgtggacgtcatg
gccccggaaccgtccgtccacaagctggcggaagcgctcgccgacttcggcctccgacgc
cgtgctgccgcgctggaggcgggggacgcggtgacccggcccagcgagcggaggccgggg
gcacggcggaggcgaacgacgacctga
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