Streptomyces spongiicola: DDQ41_20730
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Entry
DDQ41_20730 CDS
T06937
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sspo
Streptomyces spongiicola
Pathway
sspo00290
Valine, leucine and isoleucine biosynthesis
sspo00660
C5-Branched dibasic acid metabolism
sspo01100
Metabolic pathways
sspo01110
Biosynthesis of secondary metabolites
sspo01210
2-Oxocarboxylic acid metabolism
sspo01230
Biosynthesis of amino acids
Module
sspo_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sspo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
DDQ41_20730 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
DDQ41_20730 (leuC)
Enzymes [BR:
sspo01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
DDQ41_20730 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
DDQ41_20730 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
AWK10929
UniProt:
A0A2S1Z3I6
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All DBs
Position
4711183..4712616
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AA seq
477 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRQNGRRVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLTRPRTMAITVEGELPEGVTA
KDLILAIIARIGTGGGQGYVLEYRGSAIEKLSMEARMTVCNMSIEAGARAGMIAPDRTTF
DYLEGRDHAPRGAEWDAAVAYWETLRTDDDAVFDAEVFIDAAELSPFVTWGTNPGQGAPL
SASVPDPASYEDASERHAAEKALEYMGLTAGQPLRDIRVDTVFVGSCTNGRIEDLRAAAD
VLGGRKVADGVRMLVVPGSVRVALQAVEEGLDKVFKAAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLTDASATPAPAGV
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
atgggcaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgccgagggc
gagccagacctcctcttcatcgatctccatctcctgcacgaggtgacgagcccgcaggcg
ttcgacggtctccgccagaacggccggcgggtgcggaggctcgacctcaccatcgctacc
gaggaccacaacaccccgacgctggacatcgacaagcccatcgcggacccggtgtcccgg
gcccagctggagaccctgcgcaagaactgcgcggagttcggggtccggctgcacccgctg
ggcgacgtcgagcagggcgtggtgcacgtggtggggccgcagctggggctgacccagccg
ggtaccacggtggtctgcggcgattcccacacctcgacccatggcgctttcggcgcgctg
gcgttcgggatcggcacctcgcaggtcgagcacgtgctggccacccagacgctgcccctg
acgcgccccaggacgatggcgatcaccgtcgagggggaactgcccgaaggggtcaccgcc
aaggacctgatccttgccatcatcgccaggatcggcaccggcggcggccagggctacgtc
ctggagtaccggggctccgccatcgagaagctctcgatggaggcgcgcatgaccgtctgc
aacatgtcgatcgaggccggcgcccgggcgggcatgatcgcccccgaccggaccacgttc
gactacctggagggacgcgaccacgcacccaggggcgcggagtgggatgccgcggtcgcc
tactgggagaccctgcgcaccgacgacgacgcggtcttcgacgccgaggtgttcatcgac
gccgccgaactgtcccccttcgtcacctggggcaccaaccccggccagggcgcaccgctg
tccgccagtgtccccgacccggcgtcgtacgaggacgcatcggagcgccacgccgccgaa
aaggccctggagtacatggggttgaccgccgggcagccgctgcgcgacatccgggtcgac
accgtcttcgtaggctcctgcaccaacggccgtatcgaggacctgcgcgccgccgcggac
gtcctcggcggccgcaaagtcgccgacggcgtgcggatgctggtcgtccccggctcggta
cgcgtcgcgctccaggccgtcgaggagggcctggacaaggtcttcaaggcggcgggtgcc
gaatggcggcacgcgggttgctcgatgtgcctgggcatgaaccccgaccagctcgctccc
ggggagcgctcggcctccacctccaaccgcaacttcgaggggcgccagggcaagggcggc
cgcacccatctggtctcgccgcaggtcgccgccgccaccgcggtcctcggccacctcgcc
tcccccgccgacctgaccgacgcgtccgccacgcccgcaccagccggagtctga
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