Streptomyces sp. SirexAA-E: SACTE_2778
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Entry
SACTE_2778 CDS
T01601
Name
(GenBank) Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
ssx
Streptomyces sp. SirexAA-E
Pathway
ssx00860
Porphyrin metabolism
ssx01100
Metabolic pathways
ssx01110
Biosynthesis of secondary metabolites
ssx01120
Microbial metabolism in diverse environments
ssx01240
Biosynthesis of cofactors
Module
ssx_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
ssx_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
ssx_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
ssx00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
SACTE_2778
Enzymes [BR:
ssx01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
SACTE_2778
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
SACTE_2778
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AEN10659
UniProt:
G2NCF2
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Position
complement(3119726..3121393)
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AA seq
555 aa
AA seq
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MSPTGPVVSDFPVLSSGHVTFLGAGPGDPGLLTLRAVEALASADVLVAEPDVLDVVRGHA
RAGVSTPEMTVVDTSSTAVGVPVLRDAVNLVMEGVKGGRRVVRAVSGDPGMDGDAGAEML
ACAAAGVPFEVVPGVANAVGVPAYAGVPLRDAQGADVRFVDARTASDRCWSEVGASDATA
VVSTSLDSVAAAAGELVSAGRKPDTPMTVTVAGTTTRQRTWTATLGTIGQVLKQAKVLPS
PEGHRPVIAVVGERSSAAQRDQLSWFESKPLFGWKVLVPRTKEQAASLSDQLRSYGAVPH
EVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIK
VAAVGEQTAAALIDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATET
LVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKP
HNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVHKLAQALADFGAQRRDAAKEAGDPVTR
PSERRPGARRRRTTT
NT seq
1668 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccggccccgtcgtatccgacttccctgtcctgtcctcagggcacgtcacc
ttcctcggcgccggtcccggcgacccgggactgctgactctgcgcgctgtcgaggcgctc
gcgagcgcggacgtccttgtcgccgagcccgatgtgctcgacgtcgttcgcggccatgcc
cgggcaggggtgagcacgcctgagatgacggtagttgacacttcgtcaacagccgtcggg
gtacccgttctcagggatgcggtcaatcttgtcatggagggtgtgaagggcggcaggcgg
gtggtccgtgccgtcagcggcgacccgggcatggacggcgacgcgggcgcggagatgctc
gcctgcgccgccgcgggtgtgccgttcgaggtggtgcccggggtcgcgaacgccgtgggt
gtgccggcgtacgccggtgtgccgctgcgggacgcccagggtgccgatgtgcggttcgtg
gacgcccgtaccgcttcggaccgttgctggtccgaggtcggggcgagcgacgcgacggcc
gtggtgtccacgtcgctggactcggtggccgcggccgccggggagctggtgtcggcgggc
cgcaagccggacaccccgatgacggtgacggtggccgggacgacgacgcgccagcgcacc
tggacggcgacgctggggacgatcggccaggtgctgaagcaggccaaggtcctcccgtcg
ccggaggggcaccggcccgtgatagccgtggtcggggagcgcagctccgccgcccagcgt
gaccagctgtcgtggttcgagtccaagccgctgttcggctggaaggtgctcgtgccgcgt
accaaggagcaggcggcgtcgctctccgaccagctgcgctcctacggcgcggtgccgcac
gaggtaccgacgatcgccgtcgagccgccgcgtacgccccagcagatggagcgcgcggtc
aagggcctggtgacgggccggtacgagtggatcgccttcacctcggtcaacgcggtcaag
gccgtgcgggagaagttcgaggagtacgggctcgacgcccgtgccttcgccgggatcaag
gtggcggccgtcggtgagcagaccgccgccgcgctgatcgacttcggtgtgaagccggac
ctggtgccgtcgggtgagcagtcggccgccggtctgctggaggactggccgccgtacgac
ccggtcttcgacccgatcgaccgggtgttcctgccgcgtgcggacatcgccacggagacg
ctggtggccgggctgatcgagctgggctgggaggtcgacgacgtgaccgcgtaccgcacg
gtgcgtgcctcgccgccgccggccgagacccgtgaggcgatcaagggcggcggtttcgac
gcggtgctcttcacctcgtcctcgaccgtgcgcaacctggtcgggatcgcgggcaagccg
cacaacgtgacggtgatcgcgtgtatcggcccggcgacggccaagaccgcggaggagcac
ggcctgcgggtggacgtcctgtccccggagccgtcggtccacaagctggcccaggcgctg
gcggacttcggcgcgcagcgccgggacgcggcgaaggaggccggtgacccggtgacgcgt
ccgagcgagcgccgccccggcgcgcggcggcgccggacgacgacctga
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