Saccharothrix syringae: EKG83_44615
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Entry
EKG83_44615 CDS
T06258
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
ssyi
Saccharothrix syringae
Pathway
ssyi00860
Porphyrin metabolism
ssyi01100
Metabolic pathways
ssyi01110
Biosynthesis of secondary metabolites
ssyi01120
Microbial metabolism in diverse environments
ssyi01240
Biosynthesis of cofactors
Module
ssyi_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
ssyi_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
ssyi_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
ssyi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
EKG83_44615
Enzymes [BR:
ssyi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
EKG83_44615
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
EKG83_44615
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
QFZ23585
UniProt:
A0A5Q0HCB6
LinkDB
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Position
complement(10526115..10527647)
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AA seq
510 aa
AA seq
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MTRARKTPGRVAFVGSGPGDTGLLTVRARDLFAKAEVVVTDPDVPAEVVALVPDGVEVRP
AVGDPADVARDLVAEAKNGAAVVRLVAGDPLTLDSVVKEAHAVSKTTIAFDVVPGVPAGT
AVPAYAGVALGAVHTEADVRGVTDWASLASAPGTLVLHATGSHLAEAASSLVEHGVAPQT
PVSVTADGTGFSQRTIDTTLAGLAQDAGDLTGPLVVTVGAAVANRTKLSWWESRALYGWR
VLVPRTKEQAGAMSDRLHSHGAIPVEVPTISVEPPRSPAQMERSVKGLVDGRYQWVVFTS
TNAVRAVWEKFREFGLDARAFSGVKIACVGEATAAKVRGFGIIPELVPSGEQSSEGLLAD
FPPYDDILDPVDRVLLPRADIATETLAAGLRERGWEIDDVTAYRTVRAAPPPADTREMIK
SGGFDAVCFTSSSTVRNLVGIAGKPHARTLVACIGPQTAETAREFGLRVDVQPEDANVPA
LVDALAQHAARLRAEGALPPPRRTKRLRRS
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
atgacccgcgcacgcaagacccccggccgagtcgccttcgtgggctccggccccggcgac
accgggctgctcaccgtccgggcccgtgacctgttcgccaaggcggaggtcgtggtgacc
gacccggacgtaccggccgaggtggtggcgctggtaccggacggcgtcgaggtccgcccg
gccgtgggcgaccccgccgacgtcgccagggacctggtcgccgaggcgaagaacggcgcc
gccgtggtgcgcctggtggcgggtgacccgctgaccctggactccgtggtgaaggaggcc
cacgcggtctccaagaccaccatcgccttcgacgtggtgccgggcgtcccggcgggcacg
gccgtcccggcctacgccggcgtcgccctgggcgcggtgcacaccgaggccgacgtccgg
ggcgtgaccgactgggcgagcctggcctccgcaccgggcaccctcgtcctgcacgccacc
ggcagccacctggccgaggcggcgtcgtccctggtcgaacacggtgtggccccgcagacc
ccggtctcggtgaccgccgacggcaccggtttcagccagcgcacgatcgacaccaccctg
gccggcctggcccaggacgccggcgacctgaccggccccctggtcgtcacggtgggcgcc
gcagtggccaaccgcaccaagctgtcctggtgggagtcccgcgccctgtacggctggcgc
gtcctcgtcccgcgcaccaaggagcaggccggcgcgatgagcgaccgcctgcactcccac
ggcgccatcccggtcgaggtgcccaccatctcggtggagcccccgcgcagcccggcccag
atggagcgctcggtgaagggactggtggacggccgctaccagtgggtcgtcttcacctcg
accaacgccgtccgcgcggtctgggagaagttccgcgagttcggcctggacgcccgagcc
ttctccggcgtcaagatcgcctgcgtcggcgaggcgaccgcggccaaggtccggggcttc
ggcatcatcccggaactggtgccgagcggcgagcagtcctcggagggcctcctggccgac
ttcccgccgtacgacgacatcctcgacccggtggaccgagtcctgctcccccgagcggac
atcgccaccgagaccctggccgcaggactgcgcgaacgaggctgggaaatcgacgacgtc
accgcctaccgcaccgtccgcgcggccccgcccccggcggacacccgagaaatgatcaag
tccggcggcttcgacgcggtctgcttcacctcgtcctcgaccgtccgcaacctggtcggc
atcgccggcaagccgcacgcccgcaccctggtggcctgcatcggcccccagaccgcggaa
acggcccgcgagttcggcctccgcgtcgacgtccaaccggaagacgccaacgtcccggcc
ctggtggacgccctggcccagcacgcggcccgcctgcgcgcggagggcgccctcccaccc
ccgcgcaggaccaagcgcctccgccgctcctga
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