Streptomyces tanashiensis: LDH80_22685
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Entry
LDH80_22685 CDS
T08718
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
staa
Streptomyces tanashiensis
Pathway
staa00860
Porphyrin metabolism
staa01100
Metabolic pathways
staa01110
Biosynthesis of secondary metabolites
staa01120
Microbial metabolism in diverse environments
staa01240
Biosynthesis of cofactors
Module
staa_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
staa_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
staa_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
staa00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
LDH80_22685
Enzymes [BR:
staa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
LDH80_22685
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
LDH80_22685
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
UZX23353
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Position
4992432..4994102
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AA seq
556 aa
AA seq
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MNPTRPTTSPVSSAFTGHGHVTFLGAGPGDPGLLTLRAVEALSGADVLIAEPEVLEVVRG
HARAGVSTPELTVVDEASTTAGVPVLRDAANLVMEAARGGRRVVRAVTGDPGLDGNAGAE
MLACAAEGIPFEVVPGVATAVGVPAYAGVPLRDAQGTDVRFVDARTADERCWAEVGASDG
TVVVSTSLDAVAAAAGELVSAGRKPDTPLTVTIAGTTTRQRTWNATLGTIAQVFKQGKVL
PSPEGHRPVIAVVGERSAPAQRDQLSWFESKPLFGWRVLVPRTKEQAASLSDQLRSYGAV
PHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAG
IKVAAVGEQTAAALVDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIAT
ETLVAGLIELGWEVDDVTAYRTVRASPPPADTREAIKGGGFDAVLFTSSSTVRNLVGIAG
KPHNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVHKLAEALADFGLRRRESALEAGDPV
TRPSERRPGARRRRTT
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
ttgaaccccacccgcccgaccacaagccctgtgtcctcggccttcaccggccacggacac
gtcacgttcctcggcgcaggccccggtgaccccggactgctgaccctcagggctgtcgaa
gccctgtcgggagcggacgtcctgatcgccgagcccgaggtgctcgaggtcgttcgcggc
cacgcgcgcgcgggggtgagcacgcctgagctgacggttgttgacgaggcgtcaacaacc
gccggtgtccccgtgttgagggatgcggccaatcttgtcatggaggccgcgaggggcggc
aggcgggtcgtccgtgcggtgacgggcgaccccggactcgacgggaacgcgggagccgag
atgctcgcctgcgccgccgagggcatccccttcgaggtcgtccccggcgtcgccaccgcc
gtcggcgtgcccgcgtacgccggtgtgccgctgcgcgacgcacagggcaccgacgtgcgc
ttcgtcgacgcccgcaccgccgacgagcggtgctgggccgaggtcggcgcctcggacggg
accgtcgtcgtgtccacgtccctcgacgcggtcgccgcggcggccggtgaactggtgtcg
gcaggccgtaagccggacaccccgctcaccgtcaccatcgccggtacgaccacccgccag
cggacctggaacgcgaccctcgggacgatcgcccaggtcttcaagcagggcaaggtgctc
ccctcgcccgagggccaccggccggtcatagccgtggtcggcgagcgcagcgccccggcg
cagcgggaccagctgtcgtggttcgagtcgaagccgctcttcgggtggcgggtcctcgtg
ccgcgcaccaaggagcaggccgcgtcgctctccgaccagctgcgttcgtacggcgcggtg
ccgcacgaggtgccgacgatcgccgtcgagccgccgcgcaccccgcagcagatggagcgg
gcggtcaaggggctcgtcaccggacgctacgagtggatcgccttcacctcggtgaacgcg
gtgaaggccgtacgggagaagttcgaggagtacgggctcgacgcccgcgccttcgccggg
atcaaggtcgcggccgtgggtgagcagaccgccgcggctctggtcgacttcggcgtgaag
ccggacctggtgccgtcgggcgagcagtccgcggccggactcctcgaggactggccgccg
tacgacccggtcttcgacccgatcgaccgcgtcttcctgccgcgcgccgacatcgcgacc
gagacgctggtcgcggggctcatcgagctcgggtgggaggtcgacgacgtcaccgcctac
cggaccgtacgggcctcgccgccgccggcggacacgcgggaggcgatcaagggcggcggt
ttcgacgccgttctgttcacgtcctcctcgacggtgcggaacctggtcggtatcgccggg
aagccgcacaacgtgacagtcatcgcctgcatcggtcccgccacggccaagacggccgag
gagcacgggctgcgggtcgacgtgctctcgcccgagccgtccgtccacaagctcgccgag
gcgctggcggacttcggtctgcggcggcgggagtccgcgctggaggcgggggatccggtg
acgcggccgagcgagcggcggccgggcgcgcggaggcgtcgcacgacgtag
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