Streptomyces tendae: F3L20_02230
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Entry
F3L20_02230 CDS
T09112
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
stee
Streptomyces tendae
Pathway
stee00860
Porphyrin metabolism
stee01100
Metabolic pathways
stee01110
Biosynthesis of secondary metabolites
stee01120
Microbial metabolism in diverse environments
stee01240
Biosynthesis of cofactors
Module
stee_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
stee_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
stee00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
F3L20_02230
Enzymes [BR:
stee01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
F3L20_02230
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
F3L20_02230
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QER84835
UniProt:
A0A5P1YEH1
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Position
467857..469554
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AA seq
565 aa
AA seq
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MSPTTLPAPPEQGHVTFLGAGPGDPGLLTLRAVEALANADVLVAEHDVLDVVRTHARQGV
SEVHTDADTSAPGTGTPQLTVVDGASTTAGVPSMRDAAHLVMEAARGGKRVVRAVSGDPG
LDAYAAEEMLACASAGVPFEVVPGVATAVGVPAYAGVPLRDAQGTDVRFVDARTASDRCW
TEVGASDGTVVVSTTLDSVAAAAGELVSAGRKPDTPLTVTVAGTTTRQRTWTATLGTIAQ
TLKQAKVLPSPEGGRPVIAVVGERSAAAQRDRLAWFESKPLFGWKVLVPRTKEQAASLSD
QLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYG
LDARAFAGIKVAAVGEQTANALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVF
LPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTV
RNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALADFGTRRRLA
ALEAGDPVTRPSERRPGARRRRSTT
NT seq
1698 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccactcttcccgcccctccggaacaagggcacgtcaccttcctcggtgcc
ggacccggggatccgggactgctgaccctgcgcgccgtggaggccctggcgaacgcggac
gtcctcgtcgccgagcacgacgtgctcgatgtcgtacggacgcacgccaggcagggcgtc
tccgaggtgcacacggacgcggacacgtccgcgccgggcacgggcacgccccagctgacg
gtcgttgacggcgcgtcaacaaccgccggagttccctcgatgagggatgccgcacatctt
gtcatggaggccgcgcggggcggcaagcgggtcgtccgtgcggtgtcaggcgaccccgga
ctggacgcgtacgccgccgaggagatgctggcgtgcgcctcggccggggtgccgttcgag
gtcgtgcccggtgtcgccaccgcggtcggcgtgcccgcgtacgccggtgtgccgctgcgg
gacgcccagggcaccgacgtgcggttcgtcgacgcgcggacggcgtccgaccggtgctgg
acggaggtcggcgcgtcggacggcacggtggtcgtctccaccacgctggactcggtggcc
gccgccgcgggcgaactggtgtccgccggacgtaagcccgacacccccctgacggtgacc
gtcgcgggcaccacgacccggcagcgcacctggacggcgacgctcggcacgatcgcgcag
acgctgaagcaggcgaaggtgctgccctccccggagggcggccggccggtgatagccgtg
gtcggcgagcgttccgccgccgcccagcgggaccggctggcgtggttcgagtccaagccg
ctgttcggctggaaggtgctcgtgccgcgcaccaaggagcaggcggcgtcgctctccgac
caactgcggtcctacggggccgtgccgcacgaggtgccgacgatcgccgtcgaacccccg
cgcacgccccagcagatggaacgtgccgtcaagggcctggtgaccggccgctacgagtgg
atcgccttcacctcggtcaacgcggtcaaggcggtgcgggagaagttcgaggagtacggg
ctcgacgcccgtgccttcgccgggatcaaggtcgcggcggtgggcgagcagaccgcgaac
gcgctgatcgccttcggcgtgaagccggacctggtgccgagcggcgagcagtcggccgcc
ggtctgctggaggactggccgccgtacgacccggtcttcgacccgatcgaccgtgtcttc
ctgccgcgcgccgacatcgccaccgagacgctggtcgcgggtctgatcgagctgggctgg
gaggtcgacgacgtcacggcgtaccgcaccgtgcgcgcgtcgccgccgccggcggagacc
cgtgaggcgatcaagggcggtggcttcgacgcggtgctgttcacctcgtcgtcgacggtg
cggaacctggtcggcatcgcgggcaagccgcacaacgtgacggtgatcgcgtgcatcggc
ccggccacggcgaagacggccgaggagcacgggctgcgggtggacgtgatggctcccgag
ccgtcggtccacaagctggccgaggccctggccgacttcggtacgcggcgccggctggcg
gcgctggaggcgggcgacccggtcacccggcccagcgagcggcggccgggggcgcggaga
cgtcggtcgacgacgtga
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