Streptococcus pyogenes MGAS15252 (serotype M59): MGAS15252_0924
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Entry
MGAS15252_0924 CDS
T01794
Symbol
fhs
Name
(GenBank) Formate--tetrahydrofolate ligase, Fhs
KO
K01938
formate--tetrahydrofolate ligase [EC:
6.3.4.3
]
Organism
stg
Streptococcus pyogenes MGAS15252 (serotype M59)
Pathway
stg00670
One carbon pool by folate
stg01100
Metabolic pathways
stg01120
Microbial metabolism in diverse environments
stg01200
Carbon metabolism
stg01240
Biosynthesis of cofactors
Module
stg_M00140
C1-unit interconversion, prokaryotes
Brite
KEGG Orthology (KO) [BR:
stg00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
MGAS15252_0924 (fhs)
Enzymes [BR:
stg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.3 formate---tetrahydrofolate ligase
MGAS15252_0924 (fhs)
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Gene cluster
GFIT
Motif
Pfam:
FTHFS
CbiA
DUF719
Motif
Other DBs
NCBI-ProteinID:
AFC66268
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All DBs
Position
complement(909084..910754)
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AA seq
556 aa
AA seq
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MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEKMKAVEANEPGKLILVT
AINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVMGIKGGAAGGGYAQVLPME
DINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRRIIWKRVLDLNDRALRQVIVG
LGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKRLADIVVAYTYDRKPVYVRDLKV
EGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIAHGCNSVLATSTALRLADYTVTEAG
FGADLGAEKFLNIKVPNLPKAPDAIVIVATLRALKMHGGVAKSDLAAENCEAVRLGFANL
KRHVENMRQFKVPVVVAINEFVADTEAEIATLKALCEEIKVPVELASVWANGAEGGLALA
KTVVCVIDQEAADYKRLYSDEDTLEEKVINIVTQIYGGKAVQFGPKAKTQLKQFAEFGWD
KLPVCMAKTQYSFSDNPSLLGAPTDFDITIREFVPKTGAGFIVGLTGDVMTMPGLPKVPA
AMAMDVAENGTALGLF
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
atgaaatcagatatcgaaattgcccaaagtgtcgccttacaaccaatcactgacattgtt
aaaaaggttggaatagacggcgatgacattgagctttatggcaaatataaggctaaattg
tcttttgagaaaatgaaagctgtcgaagctaatgagcctggaaaattaatcttggtaact
gctattaaccctactccagcaggagaaggaaaatcaaccatgtctattggactggcagat
gccttaaatcaaatgggaaaaaaaaccatgcttgccttacgtgaaccctcccttggtcct
gttatggggattaaaggcggggcagcaggtggtggctatgcccaagtattgcctatggaa
gacattaatcttcactttactggtgacatgcatgccattacaaccgctaataatgcatta
tctgctttgattgacaatcatttgcagcaaggaaacgatttaggaattgatcctcgccgc
attatttggaagcgcgtgttggaccttaatgatcgcgctcttcgtcaggtaattgttggc
ttaggtagtccagtgaatggtgtgccacgcgaagatgggtttgatatcacagtagcttct
gaaatcatggcaattttatgtttggcaactgacttaaaagatctaaagaaacgtcttgct
gatatcgtcgtggcttatacctatgatcgtaagcctgtctatgtgcgtgacttgaaggtt
gaaggagcattgacattaattctaaaagatgctatcaagccaaacttggtgcagactatt
tatggaacaccagctcttattcatggggggccatttgctaatattgctcatggttgtaat
tctgtccttgctacctcaacagctttgcgattagcagattacactgttaccgaagcagga
ttcggggccgacctaggagctgaaaaattcctaaatatcaaagtacctaatcttcctaaa
gcaccagatgctatcgtcattgttgcaaccttgcgcgcccttaaaatgcatggaggtgtc
gccaaatcagatttagccgctgaaaattgtgaggctgttcgcttaggatttgccaactta
aaacgtcacgtggaaaacatgcgccaattcaaagttccagttgtggtggctatcaatgaa
tttgtagcagataccgaggctgaaattgctaccttaaaagcgctttgtgaagagattaag
gttccagtagaattagccagtgtttgggcaaatggagctgagggaggcttagcattagct
aaaacagtggtttgtgtgattgatcaagaagctgctgactacaaacgtctctattcagat
gaggatactttggaagaaaaagtgatcaatatcgttacccagatttatggtggcaaagct
gttcaatttggccccaaggccaaaacacaactgaagcagttcgcagaattcggttgggat
aaattgcctgtttgtatggctaagacccaatacagtttttcagataacccatccttgctt
ggagcgccaaccgattttgacattaccattcgtgaatttgttcctaaaacaggagcaggt
tttattgttggtttaacaggtgatgtgatgaccatgcctggtttgcctaaagttccagct
gccatggcaatggacgtagcagaaaatggcacagccctcggtctcttttag
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