Streptomyces sp. CCM_MD2014: NI25_16730
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Entry
NI25_16730 CDS
T04862
Name
(GenBank) uroporphyrin-III methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
strd
Streptomyces sp. CCM_MD2014
Pathway
strd00860
Porphyrin metabolism
strd01100
Metabolic pathways
strd01110
Biosynthesis of secondary metabolites
strd01120
Microbial metabolism in diverse environments
strd01240
Biosynthesis of cofactors
Module
strd_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
strd_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
strd00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
NI25_16730
Enzymes [BR:
strd01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
NI25_16730
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
NI25_16730
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Motif
Pfam:
HEM4
TP_methylase
RodZ_C
Motif
Other DBs
NCBI-ProteinID:
AIV34952
UniProt:
A0A0N6ZJX6
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Position
complement(3841492..3843189)
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AA seq
565 aa
AA seq
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MSPTTLPAGPEHGHVTFLGAGPGDPGLLTLRAVEALAHADVLVAEHEVLDVVRTHARQGV
SEVHTDADPADPGTGAPQLTVVDGASTTLGAPAVRDAAHLVMEAARGGRRVVRAVTGDPG
LDAYAAEEMLACAAAGVPFEVVPGIANAVGVPAYAGVPLRDAEGADVRFVDARTASDRCW
TEVGASDGTVVVSTTLDSVAAAAGELVSAGRKPDTPLTVTIAGTTTRQRTWTATLGTVAQ
TLKQAKVLPSPDGGRPVIAVVGERSATARRDQLSWFESKPLFGWKVLVPRTKEQAASLSD
QLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYG
LDARAFAGIKVAAVGEQTANALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVF
LPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPATTREAIKGGGFDAVLFTSSSTV
RNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALADFGLRRRAA
ALEAGDPVTRPSERRPGSRRRRSST
NT seq
1698 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccacccttcccgccggtccggaacacgggcacgtcaccttcctcggtgcc
ggacccggagatccgggactgctgactctgcgcgccgtggaggcgctggcccacgcggac
gtcctcgtcgccgagcacgaggtgctcgacgtcgtgcgtacgcacgcgaggcagggcgtg
tcggaggtgcacacggatgccgatccggcggatccgggcacaggcgcgccccagctgacg
gttgttgacggtgcgtcaacgaccctcggcgcccccgctgtgcgggatgccgcacatctt
gtcatggaggccgcgcggggcggcaggcgggtggtgcgtgcggtgaccggtgaccccggg
ctcgacgcgtacgccgccgaggagatgctggcgtgcgccgcggccggggtgccgttcgag
gtcgtcccgggcatcgcgaacgccgtcggcgtgcccgcgtacgccggtgtgccgctgcgg
gacgcggagggcgcggacgtgcggttcgtggacgcccgtacagcgtcggaccgctgctgg
accgaggtgggcgcctccgacggcacggtggtggtgtcgacgacgctggactcggtggcc
gcggcggccggcgagctggtctcggcgggccgcaagccggacaccccgctgacggtgacg
atcgccggtacgacgacgcggcagcgcacctggacggcgacgctgggcacggtcgcccag
accctgaagcaggcgaaggtgctgccgtccccggacggcggccgcccggtgatagccgtg
gtcggcgagcgcagcgcgaccgcccggcgcgaccagctgtcgtggttcgagtccaagccg
ctgttcggctggaaggtcctcgtcccgcgtacgaaggagcaggcggcgtcgctctccgac
cagttgaggtcctacggcgcggtcccgcacgaggtcccgaccatcgcggtggagccgccc
cgcaccccgcagcagatggagcgcgcggtcaagggcctggtcacgggccgctacgagtgg
atcgctttcacgtcggtcaacgcggtgaaggcggtccgcgagaagttcgaggagtacggc
ctggacgcccgcgccttcgcgggcatcaaggtcgcggcggtcggcgagcagacggccaac
gccctcatcgccttcggcgtgaagccggacctggtcccgagcggcgagcagtcggcggcg
ggcctcctggaggactggcccccctacgacccggtcttcgacccgatcgaccgcgtcttc
ctcccccgcgccgacatcgccaccgagaccctggtcgccggcctgatcgagctgggctgg
gaggtcgacgacgtcaccgcgtaccgcacggtgcgcgcctcgccgcccccggccacgacc
cgggaggccatcaagggcggcggcttcgacgcggtgctcttcacgtcgtcgtccacggtc
cgcaacctggtcggcatcgcgggcaagccgcacaacgtcacggtgatcgcctgcatcggc
ccggccacggcgaagacggccgaggaacacggcctgcgcgtcgacgtgatggcccccgaa
ccgtccgtccacaagctggcggaggccctggccgacttcggcctgcgccgccgggctgcg
gccctggaggcgggggacccggtgacccggccgagcgaacggcggccggggtcgcggaga
cggcggtcttcgacctga
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