Streptomyces tsukubensis: B7R87_19335
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Entry
B7R87_19335 CDS
T07155
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
stsu
Streptomyces tsukubensis
Pathway
stsu00860
Porphyrin metabolism
stsu01100
Metabolic pathways
stsu01110
Biosynthesis of secondary metabolites
stsu01120
Microbial metabolism in diverse environments
stsu01240
Biosynthesis of cofactors
Module
stsu_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
stsu_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
stsu_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
stsu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
B7R87_19335
Enzymes [BR:
stsu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
B7R87_19335
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
B7R87_19335
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AZK95771
UniProt:
A0A5H2U8N5
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Position
4658818..4660482
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AA seq
554 aa
AA seq
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MSPTTNLSTAYDSAHGHVTFLGAGPGDPGLLTLRAVEALAGADVLIAEPDVLDVVRGHAR
ASVSTPELTVVDDASTAAGIPVLRDAVNLVMEAARSGRRVVRAVSGDPGLDADAGHEMLA
CAAEGIPFEVVPGIAAAVGVPAYAGVPLRDAQGADVRFVDARTASERCWSEVGASDGTVV
VSTTLDAVAAAAGELVAAGRKPDTPLTVTVAGTTTRQRTWTATLGTIAQVFKQGKVLPSP
EGHRPVIAVVGERSAPAQRDQLAWFESKPLFGWKVLVPRTKEQAASLSDQLRSYGAVPHE
VPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKV
AAVGEQTAKALIDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETL
VAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKPH
NVTVIACIGPATAKTAEEHGLRVDVLSPEPSVHRLAEALAEFGAGRRAAAVEAGEHVTRP
SERRPGGRRRRTTT
NT seq
1665 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccaccaacctgtccacggcgtacgactcggcacacgggcacgtcactttc
ctcggcgccggtcccggtgatccgggactgctgaccctgcgggctgtcgaggcactcgcg
ggagccgatgtcctgatcgccgagcccgatgtgctcgacgtggttcgcggccacgcgcgg
gcgagcgtcagcacgcctgagctgacggttgttgacgatgcgtcaacagccgccggaatc
cccgtactcagggatgcggtcaatcttgtcatggaggccgcgcgctccggcaggcgggtc
gtgcgagcggtgagcggcgatcccggtctcgacgccgacgccggtcacgagatgctggcc
tgcgccgcggagggcattcccttcgaggtggtgcccggtatcgcggcggcggtgggcgtg
cccgcctatgccggggtgccgctgcgggacgcgcagggcgcggacgtccgcttcgtcgac
gcccggaccgcgagtgagcgctgctggtcggaggtgggtgcgagcgacggtacggtcgtg
gtctccaccacgctcgacgcggtcgccgcggcggcgggtgagctggtcgcggcgggccgc
aagccggacaccccgctgaccgtcacggtcgccgggaccacgacccggcagcggacctgg
accgcgacgctcggcacgatcgcgcaggtcttcaagcagggcaaggtgctgccgtctccg
gaggggcaccgcccggtgatagcggtggtcggtgagcgcagcgcgcccgcgcagcgcgat
cagctcgcgtggttcgagtccaagccgctgttcggctggaaggtgctcgtgccgcggacg
aaggagcaggcggcttcgctgtcggaccagttgcgttcgtacggtgcggtgccgcacgag
gtgccgacgatcgcggtcgagccgccgcgtaccccgcagcagatggagcgggcggtcaag
ggcctggtcacgggccggtacgagtggatcgccttcacctcggtgaacgcggtcaaggcg
gtccgggagaagttcgaggagtacgggctcgacgcccgcgccttcgccgggatcaaggtc
gcggcggtcggtgagcagaccgcgaaggcgctgatcgacttcggcgtcaagccggatctg
gtgccgagcggcgagcagtcggccgcggggctgctggaggactggccgccgtacgacccg
gtcttcgacccgatcgaccgggtgttcctgccgcgtgcggacatcgcgaccgagacgctg
gtcgcgggcctgatcgaactgggctgggaggtcgacgacgtcacggcctaccggacggtg
cgggcctcgccgccgccggcggagacccgcgaggcgatcaagggcggcggtttcgacgcg
gtgctgttcacctcgtcgtcgaccgtacggaatctggtcgggatcgccgggaagccgcac
aacgtgacggtgatcgcgtgtatcggcccggcgacggcgaagaccgcggaggagcacggg
ctgcgggtggacgtgctgtcgccggagccttcggtgcaccggctggcggaggcgctggcg
gagttcggcgcggggcgccgggcggccgcggtcgaggcgggcgagcatgtgacccggccg
agtgagcggcgcccgggcggccgcaggcggcggacgacgacctga
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