Streptomyces tubbatahanensis: MMF93_24235
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Entry
MMF93_24235 CDS
T08938
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
stub
Streptomyces tubbatahanensis
Pathway
stub00290
Valine, leucine and isoleucine biosynthesis
stub00660
C5-Branched dibasic acid metabolism
stub01100
Metabolic pathways
stub01110
Biosynthesis of secondary metabolites
stub01210
2-Oxocarboxylic acid metabolism
stub01230
Biosynthesis of amino acids
Module
stub_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
stub00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MMF93_24235 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MMF93_24235 (leuC)
Enzymes [BR:
stub01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MMF93_24235 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MMF93_24235 (leuC)
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Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
UNS99219
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Position
5598582..5600006
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRVEGEPDLLFIDLHLLHEVTSPQAFDGLRKAGRGVRRTDLTLAT
EDHNTPTLDIDKPIADPVSRTQLETLRKNCADFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPMAPFKTMAVTVNGELPEDVTA
KDLILAIIARIGTGGGQGYVIEYRGEAIEKLSMEARMTICNMSIEAGARAGMIAPDETTY
RYVEGREHAPQGEEWEAAVAYWKTLRTDEDAVFDHEVVIEASELAPFVTWGTNPGQGAPL
SQAVPDPATFQDVSAKLAAEKALEYMGLSAGQPLREVTVDTVFVGSCTNGRIEDLRSAAT
VLEGRSVADGVRMLVVPGSVRVALQAVEEGLDKVFTAAGAEWRHAGCSMCLGMNPDQLQP
GERAASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLADVREPATV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggacgcacactcgcggagaaagtctgggacgaccacgtcgtcaggcgcgtggaaggc
gagccggacctgctcttcatcgatctccacctgctccacgaggtgaccagcccgcaggcc
ttcgacggccttcgcaaggcgggccgcggcgtgcggcgcaccgacctgaccctcgcgacc
gaggaccacaacaccccgaccctggacatcgacaagccgatcgccgacccggtctcacgc
acccagctggagacgctgcgcaagaactgcgccgacttcggcgtcaggctgcacccgctg
ggcgacgtcgagcagggcgtcgtccacgtcgtcggcccgcagctggggctgacgcagccg
ggcaccacggtggtctgcggcgacagccacacctccacccacggcgccttcggggcgctc
gccttcgggatcggcacctcgcaggtcgagcacgtgctggccacgcagacgctgccgatg
gcgccgttcaagaccatggcggtcaccgtgaacggcgagctgcccgaggacgtcaccgcc
aaggacctgatcctggcgatcatcgcccgcatcggcaccggcggcggccagggctatgtg
atcgagtaccgcggcgaggccatcgagaagctgtcgatggaggcccggatgacgatctgc
aacatgtccatcgaggcgggcgcccgcgccggaatgatcgccccggacgagacgacgtac
cgctacgtcgagggccgcgagcacgccccgcagggcgaggagtgggaggcggcggtcgcc
tactggaagacgctgcgcaccgacgaggacgccgtcttcgaccacgaggtggtcatcgag
gcctccgagctggcgccgttcgtcacctggggcaccaacccgggccagggcgccccgctg
tcccaggcggtgccggacccggccaccttccaggacgtcagtgcgaaactggccgccgag
aaggccctggagtacatgggcctgagcgccggtcagccgctgcgcgaggtcaccgtggac
accgtcttcgtcggctcgtgcaccaacggccgcatcgaggacctgcgttcggcggccacc
gtgctggagggccgcagcgtggcggacggtgtgcggatgctggtggtacccgggtccgtc
cgggtggcgctgcaggccgtcgaggaggggctggacaaggtgttcaccgccgccggcgcc
gagtggcggcacgcaggatgctcgatgtgcctgggcatgaaccccgaccagctccagccg
ggtgagcgcgccgcctccacctcgaaccgcaacttcgagggcaggcagggcaagggcggg
cgcacccacctggtctcgccgcaggtcgcggcggcgacggcggtactgggccatctggcc
tcgcccgccgacctggccgacgtccgcgaaccggcaacggtctga
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