Streptomyces tubercidicus: STRTU_003848
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Entry
STRTU_003848 CDS
T09099
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
stud
Streptomyces tubercidicus
Pathway
stud00860
Porphyrin metabolism
stud01100
Metabolic pathways
stud01110
Biosynthesis of secondary metabolites
stud01120
Microbial metabolism in diverse environments
stud01240
Biosynthesis of cofactors
Module
stud_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
stud_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
stud00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
STRTU_003848
Enzymes [BR:
stud01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
STRTU_003848
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
STRTU_003848
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
WAU13359
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All DBs
Position
4423685..4425343
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AA seq
552 aa
AA seq
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MNPTAPNHSASGQVTFLGAGPGDPGLLTLRAVEALASADVLIADPQVLDVVRVHARAQVD
TPLQASADEASIPVTSNGVSALRDTANLVMAAARAGKRVVRAVTGDPGLDGYVAEEMLAC
AAEGIVFEVVPGIAAAVGVPAYAGVPLRDAEGTDVRFIDARTADARCWSEVGASDATAVV
STSLDSVAAAAGELVSGGRKPDTPLTVTVAGTTTRQRTWTATLGSVAQVLKAAKVLPSPD
GGQPVIAVVGERSAAAQRDRLSWFESKPLFGWRVLVPRTKEQAASLSDQLVSYGAVPHEV
PTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVA
AVGEQTAKALVAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETLV
AGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHN
VTVIACIGPATAKTAEEHGLRVDVMSPEPSVHKLAEALADFGAARRDAALEAGDPVTRPS
ERRPGSRRRARS
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
ttgaaccccaccgccccaaaccactccgcctccggtcaggtcaccttcctgggtgccggg
ccgggagacccgggtctgctgacgctgcgtgcagtggaggcgctggcctccgcggatgta
ctgatcgccgacccgcaggtgctggacgtcgtgcgcgtgcatgcccgcgcacaggtggac
acaccactgcaggcgtcagctgacgaggcgtcaatccccgtcacctccaacggcgtttcc
gcccttcgggacaccgccaatcttgtcatggcggccgcccgtgcgggcaagcgggtcgtc
cgtgccgtcacgggagatcccggcctcgacgggtacgtcgccgaggagatgctggcctgc
gcggccgagggcatcgtcttcgaggtcgtgcccgggatcgccgcggccgtcggcgtgccc
gcgtacgccggtgtcccgctgcgggacgccgagggcaccgacgtccgcttcatcgacgcc
cgcaccgccgatgcgcgctgctggtccgaggtcggtgccagcgacgccaccgccgtggtc
tccacctccctggactcggtggccgcggccgccggtgagctggtgtccgggggccggaag
cccgacaccccgctgaccgtcaccgtcgccggtaccaccacccgccagcgcacctggacc
gccaccctcgggtcggtcgcgcaggtgctcaaggccgccaaggtgctgccgtcgccggac
ggcgggcagccggtcatagccgtggtcggtgagcgcagtgccgccgcgcagcgcgaccgc
ctttcgtggttcgagtccaagccgctgttcggctggcgggtgctcgtgccgcgtacgaag
gagcaggccgcgtcgctctccgaccagctcgtctcgtacggcgcggtgccgcacgaggtc
ccgaccatcgccgtcgaaccgccgcgcaccccgcagcagatggagcgcgcggtcaagggc
ctggtcaccggccgctacgagtggatcgccttcacctcggtcaacgccgtcaaggccgtc
cgggagaagttcgaggagtacggcctcgatgcccgcgcgttcgccgggatcaaggtcgcc
gcggtcggcgagcagaccgccaaggcgctggtcgccttcggtgtgaagcccgacctggtg
ccgagcggtgagcagtccgccgccggtctgctggaggactggccgccctacgacccggtc
ttcgacccgatcgaccgcgtcttcctgccgcgcgccgacatcgccaccgagaccctggtc
gccgggctgatcgagctgggctgggaggtcgacgacgtcaccgcctaccggacggtgcgc
gcctcgccgccgccggccgagacccgtgaggccatcaagggcggcgggttcgacgcggtg
ctgttcacgtcctcgtcgacggtccggaacctcgtcggtatcgcgggcaagccgcacaac
gtcacggtgatcgcctgtatcggcccggccaccgccaagacggccgaggagcacgggctg
cgggtggacgtcatgtcccccgagccgtcggtgcacaagctggccgaggcgctcgcggac
ttcggcgccgcgcgccgcgatgccgccctggaggccggggacccggtcacccggcccagc
gagcggcggcccgggtcgcggcggcgggctcgtagctga
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