Streptomyces venezuelae: SVEN_3179
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Entry
SVEN_3179 CDS
T02274
Name
(GenBank) Uroporphyrinogen-III methyltransferase or Uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sve
Streptomyces venezuelae
Pathway
sve00860
Porphyrin metabolism
sve01100
Metabolic pathways
sve01110
Biosynthesis of secondary metabolites
sve01120
Microbial metabolism in diverse environments
sve01240
Biosynthesis of cofactors
Module
sve_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sve_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sve00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
SVEN_3179
Enzymes [BR:
sve01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
SVEN_3179
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
SVEN_3179
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Gene cluster
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
CCA56465
UniProt:
F2R905
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Position
complement(3474588..3476258)
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AA seq
556 aa
AA seq
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MNPTSPTTSPLSPAFAGHGHVTFLGAGPGDPGLLTLRAVEALAGADVLIAEPEVLEVVRC
HARAGVSTPELTVVDEASTTAGVPVLRDAANLVMEAARGGRRVVRAVTGDPGLDGNAGAE
MLACAAEGIPFEVVPGVATAVGVPAYAGVPLRDAQGTDVRFVDARTADERCWTEVGASDG
TVVVSTSLDSVAAAAGELVAAGRKPDTPLTVTIAGTTTRQRTWNATLGTIAQVFKQGKVL
PSPEGHRPVIAVVGERSAPAQRDQLSWFESKPLFGWRVLVPRTKEQAASLSDQLRSYGAV
PHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAG
IKVAAVGEQTAAALVDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIAT
ETLVAGLIELGWEVDDVTAYRTVRASPPPADTREAIKGGGFDAVLFTSSSTVRNLVGIAG
KPHNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVHKLAEALADFGLRRRAAALEAGDPV
TRPSERRPGARRRRTT
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
ttgaaccccaccagcccgaccaccagcccgctgtccccggccttcgcgggtcatggacac
gtcacattcctcggcgcaggccccggtgaccccggactcctgaccctcagggccgtcgag
gccctcgccggagcggatgtcctgatcgccgagccggaggtgctcgaggtcgttcgctgc
cacgcgcgcgcgggggtgagcacgccggagctgacggtcgttgacgaggcgtcaacaacc
gccggtgtccccgtgttgagggacgcggccaatcttgtcatggaggccgcgaggggcggc
aggcgggtcgtccgtgcggtgaccggcgaccccggcctcgacgggaacgcgggggccgag
atgctcgcctgcgccgccgagggcatccccttcgaggtcgtcccgggcgtggccacggcc
gtcggcgtacccgcgtacgccggtgtcccgctccgcgacgcccagggcaccgacgtgcgc
ttcgtcgacgcccgcaccgccgacgagcggtgctggaccgaggtcggtgcctccgacggc
accgtcgtcgtgtcgacgtcgctcgactcggtggccgcggccgccggtgaactggtggcg
gcaggccgtaagccggacaccccgctcaccgtcaccatcgccggtacgacgacgcgccag
cggacctggaacgcgacgctcggcaccatcgcccaggtcttcaagcagggcaaggtgctc
ccctcgcccgagggccaccggccggtgatagccgtggtcggcgagcgcagcgccccggcg
cagcgggaccagctgtcgtggttcgagtccaagccgctgttcggctggcgggtgctcgtg
ccgcggaccaaggagcaggccgcgtcgctctccgaccagcttcgttcgtacggcgcggtg
ccgcacgaggtgccgaccatcgccgtcgagccgccgcgcaccccgcagcagatggagcgg
gcggtcaaggggctcgtcaccggacggtacgagtggatcgccttcacctcggtcaacgcg
gtcaaggccgtgcgggagaagttcgaggagtacgggctcgacgcgcgtgccttcgccggg
atcaaggtcgcggcggtgggcgagcagacggccgccgcgctcgtcgacttcggtgtgaag
ccggacctcgtgccgagcggtgagcagtcggccgccggtctcctcgaggactggccgccg
tacgacccggtcttcgacccgatcgaccgcgtcttcctgccgcgggccgacatcgcgacc
gagacgctggtcgcggggctgatcgagctcgggtgggaggtcgacgacgtcaccgcctac
cggaccgtacgggcttcgccgccgccggcggacacccgggaggcgatcaagggcggcggc
ttcgacgccgtgctcttcacctcgtcgtcgaccgtgcggaacctggtcggcatcgccggg
aagccgcacaacgtgaccgtgatcgcgtgcatcgggcccgccacggccaagaccgccgag
gagcacgggctgcgggtggacgtgctgtcgcccgagccgtcggtgcacaagctcgcggag
gcgctggcggacttcggtctgcggcggcgggcggccgcgctggaggcgggcgatcccgtg
acgcggccttccgagcggcggccgggggcgcggaggcgtcgcacgacgtag
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