Streptomyces violascens: HWN34_17990
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Entry
HWN34_17990 CDS
T08842
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
svio
Streptomyces violascens
Pathway
svio00860
Porphyrin metabolism
svio01100
Metabolic pathways
svio01110
Biosynthesis of secondary metabolites
svio01120
Microbial metabolism in diverse environments
svio01240
Biosynthesis of cofactors
Module
svio_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
svio_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
svio00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
HWN34_17990
Enzymes [BR:
svio01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
HWN34_17990
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
HWN34_17990
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QLA58297
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Position
4151272..4152909
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AA seq
545 aa
AA seq
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MFSDHGHVTFLGAGPGDPGLLTLRAVEALAAADVLVAEEQVLDVVRAHARAGADMPQLSA
DEASTPAEARRFGDAANLVMGAARAGKRVVRAVQGDPGLDSEAVREMLACAAEGVTFEVV
PGIAEAVGVPAYAGIPLRDETGADVRFVDARTATERCWTELGASDGTVVVSTSLDQAAAT
AGELVAAGRKPDTPMTLTVAGTTTRQRTWEATLGTVAQVLKQAKVLPSPDGGRPVIAVVG
EHCAPARRDQLSWFESKPLFGWKVLVPRTKEQAASLSDQLRSYGAVPHEVPTIAVEPPRT
PQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVAAVGEQTAAAL
IAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETLVAGLIELGWEV
DDVTAYRTVRASPPPADTREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHNVTIIACIGPA
TAKTAEEHGLRVDVMAPEPSVHKLAEALASFGAERRAAALEAGESVARPSERRPGARRRR
AASSS
NT seq
1638 nt
NT seq
+upstream
nt +downstream
nt
atgttctccgaccatgggcacgtcaccttcctcggtgccggtcccggcgacccggggctt
ctcactctgcgcgccgtcgaggcgctggccgcggccgacgtcctggtcgcggaggagcag
gtgctcgacgtcgtcagggcgcatgccagggcgggcgcggacatgccgcaactgtccgct
gacgaggcgtcaacccccgcggaggcccgccgattcggcgatgccgccaatcttgtcatg
ggggccgcgcgggccggaaagcgggtcgtgcgcgccgtccagggcgacccggggctcgac
tccgaggccgtccgcgagatgctcgcctgcgccgccgagggcgtcaccttcgaggtggtc
cccggcatcgcggaggcggtcggcgtccccgcgtacgccggtatcccgctgcgcgacgag
accggtgccgacgtgcggttcgtggacgcgcgcaccgccaccgagcgctgctggaccgag
ctgggcgcgagcgacggaaccgtcgtcgtctccaccagcctcgaccaggcggcggccacg
gcgggcgaactggtggcggccgggcgcaagcccgacaccccgatgacgctcaccgtcgcc
gggaccaccacccgccagcggacctgggaggcgacgctcggcaccgtcgcgcaggtcctc
aagcaggccaaggtgctgccctcgcccgacggcggccgtccggtcatagccgtggtcggt
gagcactgcgccccggcccgccgcgaccagctctcctggttcgagtcgaagccgctcttc
ggctggaaggtcctggtgccgcgcaccaaggaacaggcggcctcgctctccgaccagctg
cgctcctacggcgcggtgccgcacgaggtgccgaccatcgccgtcgagccgccgcgcacc
ccgcagcagatggaacgggctgtcaagggcctggtcaccggacgctacgagtggatcgcg
ttcaccagcgtcaacgcggtcaaggcggtccgggagaagttcgaggagtacgggctcgac
gcgcgggccttcgccggcatcaaggtcgccgccgtcggcgagcagaccgcggccgcgctg
atcgccttcggcgtcaagcccgacctcgtcccctcgggcgagcagtccgcggccgggctc
ctggaggactggccgccgtacgacccggtcttcgacccgatcgaccgggtgttcctgccg
cgcgccgacatcgccaccgagaccctggtggccgggctgatcgagctgggctgggaggtg
gacgacgtcaccgcctaccggacggtgcgcgcctcgccgccgccggccgacacccgcgag
gcgatcaagggcggcggcttcgacgcggtcctgttcacctcgtcctcgaccgtccgcaac
ctggtcggcatcgcgggcaagccgcacaacgtcacgatcatcgcctgtatcgggcccgcc
accgccaagacggcggaggagcacgggctgcgcgtcgacgtgatggcgcccgagccctcg
gtgcacaagctggccgaggcgctcgcctccttcggcgcggagcgcagggccgcagcgctg
gaggccggggagagcgtcgcccggcccagcgagcggcgccccggcgcccggcgccgcagg
gccgcctcctcctcgtga
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