Streptomyces violaceusniger: Strvi_0706
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Entry
Strvi_0706 CDS
T01602
Name
(GenBank) Uroporphyrinogen III synthase HEM4
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
svl
Streptomyces violaceusniger
Pathway
svl00860
Porphyrin metabolism
svl01100
Metabolic pathways
svl01110
Biosynthesis of secondary metabolites
svl01120
Microbial metabolism in diverse environments
svl01240
Biosynthesis of cofactors
Module
svl_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
svl_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
svl_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
svl00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Strvi_0706
Enzymes [BR:
svl01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Strvi_0706
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Strvi_0706
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AEM80479
UniProt:
G2P022
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Position
509506..511164
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AA seq
552 aa
AA seq
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MNPTVPNHPGCGHVTFLGAGPGDPGLLTLRAVEALATADVLIADPQVLDVVRGHVRPGVA
ADAQGAPRQAEADGSSATVPVLRGTANLVMTAARGGKRVVRAVAGDPGLDGYAADEMLAC
AAEGILFEVVPGVAAAVGVPAYAGVPLRDAHSADVRFVDALAADERCWSEVGSSDATAVV
SATLETVAAAAGELVAAGRKPDTPLTVTVGGTTTRQRTWAATLGTIAQVLKAAKVLPSPQ
GAQPVIAVVGEQSAAGRRDQLSWFESKPLFGWKVLVPRTKEQAASLSDQLRSYGAVPSEV
PTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVA
AVGEQTARSLIDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETLV
AGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHN
VTVIACIGPATAKTAEEHGLRVDVLSPEPSVLKLAEALADFGAARRQAAIEAGEPVTRPS
ERRPGSRRRARS
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
ttgaaccccaccgtcccgaatcaccccggctgcggacacgtcaccttcctcggtgcgggc
cccggagatccgggcctgctgaccttgcgcgccgtggaggctctggccaccgcggacgta
ctgatcgccgacccgcaagtgctcgacgtggtgcgggggcacgtcaggccgggcgtggcc
gcggacgctcagggcgcgccgcggcaagcggaggctgatgggtcgtcagccaccgtcccg
gtactccggggcaccgccaatcttgtcatgacggccgcgcgcggcggcaagcgggtcgtc
cgcgcggtcgcgggcgaccccggcctcgacggatacgccgccgacgagatgctcgcctgc
gccgccgagggcatcctcttcgaggtggtgccgggtgtggccgccgcggtgggtgtgccc
gcctacgcgggggtgccgctgcgggacgcccacagcgcggatgtgcgtttcgtggacgcc
ctggccgccgatgagcgctgctggagcgaggtcggctcgtccgacgcgaccgccgtggtc
tccgcgaccctggagacggtggccgccgccgcgggtgagctggtggccgcgggccgcaag
ccggacaccccgctcaccgtcaccgtcggtggcaccaccacgcgtcagcggacctgggcc
gcgacgctggggaccatcgcccaggtgctgaaggcggccaaggtgctgccgtcgccgcag
ggcgcacagccggtgatagccgtggtcggcgagcagagcgcggccggccggcgtgatcag
ctctcctggttcgagtccaagccgctgttcggctggaaggtcctggtgccgcgcaccaag
gagcaggccgcctcgctctcggaccagttgcgcagctacggcgcggtgcccagcgaggtg
ccgacgatcgccgtggagccgccgcgcaccccgcagcagatggagcgcgcggtcaagggc
ctggtcaccgggcgctatgagtggatcgccttcacctcggtcaacgcggtcaaggcggtg
cgggagaagttcgaggagtacgggctcgacgcccgcgcgttcgccgggatcaaggtcgcg
gcggtgggcgagcagaccgccaggtcgctgatcgacttcggagtgaagcctgatctggtg
cccagcggtgagcagtccgcggccgggctgctggaggactggccgccctacgacccggtc
ttcgacccgatcgaccgggtcttcctgccgcgggccgacatcgccaccgagaccctggtc
gccgggctgatcgagctgggctgggaggtcgacgacgtgaccgcgtaccgcaccgtgcgc
gcctcgccgccgccggccgagacccgtgaggccatcaagggcggcgggttcgacgcggtg
ctcttcacctcgtcgtccaccgtgcggaacctcgtcggcatcgcgggcaagccgcacaat
gtcactgtcatcgcctgtatcggcccggccaccgcgaagaccgcggaggagcacgggctg
cgggtggacgtgctgtcgcccgagccctcggtgctcaagctcgccgaggcgctcgcggac
ttcggggcggcgcggcggcaggccgcgatcgaagccggggagccggtcacccgcccgagc
gagcgacggccgggatcacggaggagggcacgctcttga
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