Streptomyces vinaceus: CP980_15000
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Entry
CP980_15000 CDS
T06865
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
svn
Streptomyces vinaceus
Pathway
svn00860
Porphyrin metabolism
svn01100
Metabolic pathways
svn01110
Biosynthesis of secondary metabolites
svn01120
Microbial metabolism in diverse environments
svn01240
Biosynthesis of cofactors
Module
svn_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
svn_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
svn_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
svn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CP980_15000
Enzymes [BR:
svn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CP980_15000
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CP980_15000
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QEV46235
UniProt:
A0A5J6J6P4
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Position
complement(3368098..3369777)
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AA seq
559 aa
AA seq
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MNPSRPTTSAFPVAAAHGHVTFLGAGPGDPGLLTLRAVEALAAADVLIAEPEVLEVVRTH
ARAGVDTPQLTIADEVSAAAGVPVIRDAANLVMEAARSGRRVVRAVTGDPGLDGNAAEEM
LACASDGIPFEVVPGVATAVGVPAYAGVPLRGGRGDASTDVRFVDARNASARCWSEVGAS
DGTLVVSATLETVASAAAELVSAGRKPDTPLTVTVAGTTTRQRTWNATLGTIAQVFKQGK
VLPSPEGARPVIAVVGEQGAATARREELAWFESKPLFGWRVLVPRTKEQAASLSDQLRSY
GAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARA
FAGIKVAAVGEQTAAALVEFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRAD
IATETLVAGLIELGWEVDDVTAYRTVRASPPPADTREAIKGGGFDAVLFTSSSTVRNLVG
IAGKPHNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVSKLAEALAEYGAARREAAKEAG
ESVSRPSERRPGARRRRTT
NT seq
1680 nt
NT seq
+upstream
nt +downstream
nt
ttgaacccctcacgtccgaccacctccgcttttccggtcgccgccgcccacgggcacgtc
accttcctcggtgccggccccggtgacccgggtctgctgacgctccgcgccgtcgaggcg
ctcgcggccgcggacgtactgatcgcggagcccgaggtgctcgaggtcgtacgcacgcat
gcgcgcgcgggagtggacacgccgcagctgacgattgctgacgaagtgtcagcagccgcc
ggtgtcccggtgatccgagatgccgccaatcttgtcatggaggccgcgcgctccggcagg
cgggtcgtccgtgccgtcaccggtgaccccggcctcgacggcaacgcggccgaggagatg
ctcgcctgcgcgagcgacggcatccccttcgaggtggtgcccggtgtcgcgaccgccgtc
ggcgtgcccgcgtacgcgggtgtgccgctgcgcggcggccggggcgacgcgagcacggac
gtccggttcgtggacgcccgcaacgcctccgcgcgctgctggagcgaggtgggcgccagc
gacggcaccctcgtcgtctcggcgacgctggagaccgtcgccagcgcggccgccgagctg
gtgtccgccggccgcaagccggacaccccgctcacggtgaccgtcgccggtacgacgacc
cgccagcggacctggaacgccaccctcgggaccatcgcccaggtgttcaagcagggcaag
gtgctcccgtcgccggagggcgcccggcccgtgatagccgtggtcggtgagcagggcgcc
gcgaccgcgcggcgcgaggagctggcctggttcgagtcgaagccgctgttcggctggcgg
gtcctcgtaccgcgcaccaaggagcaggccgcttcgctctccgaccagctgcgttcgtac
ggtgcggtgccgcacgaggtgccgaccatcgccgtggagccgccgcgcaccccgcagcag
atggagcgggccgtgaaggggctcgtcaccggacgctacgagtggatcgccttcaccagc
gtgaacgcggtgaaggccgtacgcgagaagttcgaggagtacgggctcgacgcccgggcc
ttcgcgggcatcaaggtcgccgccgtgggcgagcagaccgccgccgcgctggtcgagttc
ggcgtcaagccggacctggtacccagcggcgagcagtccgcggccgggctgctggaggac
tggccgccgtacgacccggtcttcgacccgatcgaccgcgtcttcctgccgcgggccgac
atcgcgaccgagacgctggtcgcgggcctgatagagctcggatgggaggtcgacgacgtg
accgcgtaccggaccgtgcgcgcgtcgccgccgccggcggacacccgcgaggcgatcaag
ggcggcggcttcgacgccgttctcttcacctcgtcgagcacggtgcgcaacctggtgggc
atcgccgggaagccgcacaacgtcaccgtcatcgcctgcatcggcccggccacggccaag
acggcggaggagcacggcctgcgggtcgacgtcctgtcgccggagccgagcgtgagcaag
ctggcggaggccctggccgagtacggggccgcgcgccgcgaggcggccaaggaggccggc
gagtcggtgtcccgcccgagcgagcgccggccgggcgcccgccggcgccgtacgacctga
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