Streptomyces violaceoruber: B1H20_20095
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Entry
B1H20_20095 CDS
T05124
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
svu
Streptomyces violaceoruber
Pathway
svu00860
Porphyrin metabolism
svu01100
Metabolic pathways
svu01110
Biosynthesis of secondary metabolites
svu01120
Microbial metabolism in diverse environments
svu01240
Biosynthesis of cofactors
Module
svu_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
svu_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
svu_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
svu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
B1H20_20095
Enzymes [BR:
svu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
B1H20_20095
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
B1H20_20095
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ARF63419
UniProt:
A0A1V0UDY3
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Position
4591264..4592934
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AA seq
556 aa
AA seq
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MSPTGPAASDFPALSAQGQVTFLGAGPGDPGLLTLRAVEALASADVLVAEPDVLDVVRGH
ARAGVSTPELPVVDSSSTTAGVPVLRDAANLVMEAAKGGRRVVRAVAGDPGLDADAGAEM
LACAAAGVPFEVVPGIANAVGVPAYAGVPLRDEQGADVRFVDARTASDRCWSEVGASDAT
AVVSTTLDAVAAAAGELVSAGRKPDTPLTVTIAGTTTRQRTWTATLGTIAQVLKQAKVLP
SPEGHRPVIAVVGERSSAAQRDQLAWFESKPMFGWKVLVPRTKEQAASLSDQLRSYGAVP
HEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGI
KVAAVGEQTARALIDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATE
TLVAGLIELGWEVDDVTAYRTVRASPPPSETREAIKGGGFDAVLFTSSSTVRNLVGIAGK
PHNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVHKLAEALAAFGAQRRDAAREAGDPVT
RPSERRPGARRRRTTT
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccggccccgccgcatccgactttccggccctgtccgcccaagggcaggtc
accttcctcggcgccggtcccggcgacccgggactgctgaccctgcgcgccgtcgaagcg
ctcgcgagcgcggacgtccttgtcgccgagcccgatgtgctcgacgtcgtgcgcggccat
gcgcgggcaggcgtgagcacccccgagctgccggtcgttgactcctcgtcaacaaccgcc
ggtgtacccgttctcagggatgccgccaatcttgtcatggaggccgcgaagggcggcagg
cgggtggtccgtgccgtcgcgggcgaccccggtctggacgccgacgcgggcgccgagatg
ctggcctgcgccgccgccggggtgcccttcgaggtcgtcccgggcatcgcgaacgccgtc
ggcgtgcccgcgtacgccggggtgccgctccgtgacgagcagggcgcggacgtccgcttc
gtcgacgcccgtaccgcctccgaccgctgctggagcgaggtcggcgcgagcgacgcgacc
gccgtcgtctccaccacgctggacgcggtcgcggccgccgccggcgagctggtctcggcg
ggccgcaagcccgacaccccgctcaccgtgacgatcgcgggcaccaccacccgccagcgc
acctggacggcgaccctcgggacgatcgcccaggtcctcaagcaggccaaggtgctcccg
tcgcccgagggccaccggccggtcatagccgtggtcggagagcgcagctccgccgcccag
cgcgaccagctcgcgtggttcgagtcgaagccgatgttcggctggaaggtcctcgtcccc
cggacgaaggagcaggccgcgtcgctctccgaccagctccgctcctacggcgcggtgccg
cacgaggtcccgacgatcgccgtcgagccgccgcgtacgccccagcagatggagcgtgcg
gtcaagggcctggtcaccggccggtacgagtggatcgccttcaccagcgtgaacgcggtc
aaggcggtccgggagaagttcgaggagtacgggctcgacgcccgcgccttcgccgggatc
aaggtcgccgcggtcggcgagcagaccgcccgcgcgctgatcgacttcggcgtcaagccg
gacctggtcccctcgggcgagcagtcggcggccgggctgctggaggactggccgccctac
gacccggtcttcgacccgatcgaccgggtgttcctgccgcgcgccgacatcgccaccgag
accctggtggccggcctcatcgagctgggctgggaggtcgacgacgtcaccgcctaccgc
acggtccgcgcctcgccgccgccgtccgagacccgcgaggcgatcaagggcggcgggttc
gacgcggtcctgttcacctcgtcctcgacggtgcgcaacctggtcgggatcgcgggcaag
ccgcacaacgtgaccgtgatcgcgtgcatcggcccggccaccgcgaagaccgccgaggag
cacggcctgcgggtcgacgtgctgtccccggagccgtcggtgcacaagctcgcggaggcg
ctggccgccttcggcgcgcagcgccgggacgcggcgcgggaggccggcgacccggtgacc
cggccgagcgagcgccgtccgggcgcgcgcagacggcggacgacgacgtag
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