Thermobispora bispora: Tbis_0263
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Entry
Tbis_0263 CDS
T01236
Name
(GenBank) Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
tbi
Thermobispora bispora
Pathway
tbi00860
Porphyrin metabolism
tbi01100
Metabolic pathways
tbi01110
Biosynthesis of secondary metabolites
tbi01120
Microbial metabolism in diverse environments
tbi01240
Biosynthesis of cofactors
Module
tbi_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
tbi_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
tbi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Tbis_0263
Enzymes [BR:
tbi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Tbis_0263
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Tbis_0263
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ADG86994
UniProt:
D6Y3G5
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All DBs
Position
308202..309782
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AA seq
526 aa
AA seq
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MSSANHSLEAQSGFVAFVGAGPGDENLLTLRGADLLRRADVVIADRTLHGAMLRHCRDGA
KIVDVGEDGSPAVDAIEEAKAGRTVVRLCPGDPSFFSSVADEISACADAEVEFEIVPGVP
PATAVPTYAGIPPASGVAEFRVVDATKVEDWTPHASCEGTLVIYHGLAEAPAIAKALISG
GKPDSTPVAVVREGTVTAQHTVVSTLGRLGPDLKRADVSEPAMIVVGDAVGMRDRMSWFE
TKPLFGWRVLVPRTKEQAKELTEQLRAYGAVPEEVPTISVEPPRTPQQMDRAIKGLINGR
YEWVVFTSVNAVKALREKFEEYGLDARAFAGLKIAAVGDATARSLMDFGIRPDLVPTGEQ
SSEGLLAEWPPYDSLLDPINRVLLPRADIATDTLIAGLTELGWECDDVTAYRTVRAAPPP
APIREAIKSGGFDAVLFTSSSTVRNLIGIAGKPHNVTVIAVIGPQTAKTAQEFGLRVDVM
AEKPSVSLLAAALAEYGAKMRQAQLAAGETPRRPSQMRRGARRRAK
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
gtgagctccgcgaaccacagtctggaggcccagtccgggttcgtcgccttcgtgggagcc
gggcccggtgacgagaacctgctcacgctacgcggcgccgacctgctgcggcgggccgac
gtggtcatcgccgaccggacgctccacggcgcgatgctgcgccactgccgggacggcgcg
aagatcgtcgatgtgggcgaggacgggtcgcccgcggtcgacgcgatcgaggaggcgaag
gccgggcggaccgtggtacggctctgccccggcgacccgtcgttcttctcgtccgtggcc
gacgagatctccgcgtgcgccgacgccgaggtcgagttcgagatcgtgcccggtgtcccg
cccgccacggcggtgccgacgtacgcgggcatcccgccggcctccggggtggccgagttc
cgggtggtggacgccaccaaggtcgaggactggacgccccacgcctcctgcgagggcacc
ttagtgatctaccacgggctcgccgaggcgcccgcgatcgcgaaggcgctgatcagcggg
ggcaagccggactcgaccccggtcgcggtggtgcgcgagggcacggtgaccgcgcagcac
accgtggtctccacgctcggccggctcggccccgacctgaagcgcgcggacgtctccgag
ccggcgatgatcgtcgtcggggacgcggtgggcatgcgcgaccgcatgtcctggttcgag
accaagccgctcttcggctggcgggtgctcgtcccccgcaccaaggaacaggccaaggag
ctcaccgagcagctccgggcgtacggcgcggtcccggaggaggtgccgacgatctcggtc
gagccgccgcgcaccccgcagcagatggaccgggcgatcaagggcctgatcaacggccgt
tacgagtgggtcgtcttcaccagcgtcaacgcggtgaaggccctgcgggagaagttcgag
gagtacggcctcgacgcccgcgcgttcgccggcctgaagatcgccgccgtgggcgacgcg
accgcgcgctccctcatggacttcggcatccggcccgacctggtgccgaccggtgagcag
tcgtccgagggcctgctcgcggagtggccgccgtacgactcgctgctcgacccgatcaac
cgggtgctgctgccgcgggccgacatcgcgaccgacacgctcatcgccggcctgaccgag
ctcggctgggagtgcgacgacgtcaccgcgtaccggaccgtgcgcgccgcgcccccgccc
gcgcccatccgggaggcgatcaagagcggcgggttcgacgcggtgctgttcacctcgtcg
tccacggtgcgcaacctcatcggcatcgccggcaagccgcacaacgtcacggtgatcgcc
gtgatcggcccgcagaccgcgaagaccgcccaggagttcggcctccgggtcgacgtgatg
gccgagaagccgtcggtctccctgctcgccgcggccctggcggagtacggggccaagatg
cggcaggcgcagctcgccgccggggagacgccccgccgcccgtcccagatgcgcaggggc
gcccggcgccgggcgaagtga
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