Tepidiforma flava: O0235_10225
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Entry
O0235_10225 CDS
T08993
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
tfla
Tepidiforma flava
Pathway
tfla00290
Valine, leucine and isoleucine biosynthesis
tfla00660
C5-Branched dibasic acid metabolism
tfla01100
Metabolic pathways
tfla01110
Biosynthesis of secondary metabolites
tfla01210
2-Oxocarboxylic acid metabolism
tfla01230
Biosynthesis of amino acids
Module
tfla_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tfla00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
O0235_10225 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
O0235_10225 (leuC)
Enzymes [BR:
tfla01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
O0235_10225 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
O0235_10225 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
WBL35164
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Position
complement(1833245..1834651)
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AA seq
468 aa
AA seq
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MSTPKTIIQKIWEQHVVASEPGKPDLLFIDLHLVHEVTSPQAFEGLRLAGRRVRHPELTL
ATVDHNVPTIDRDKPWSDPLSVQQVEALRKNCEEFGIPLFGVGDIRQGIVHVIGPEQGLT
QPGMTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLPQAKPKTMSVEVTGELHPGV
TAKDVILGIIAKIGVSGGVGHVIEYRGEVIRNLSMEGRMTICNMSIEGGARAGLIAPDDT
TFAYMEGRRFAPKGADWERALDYWRSLPTDEGAEFDTYVTLDGAEIVPTVTWGTTPAQSV
PVTGRVPDPSEAPTPQARELAERALHYMGLEPGTPIQEIRLDRVFIGSCTNSRIEDLRAA
AEVVRGRKVAPHVRAMVVPGSGLVKHQAEEEGLDRIFKEAGFEWREAGCSMCLGMNPDIL
MPGERCASTSNRNFEGRQGRGGRTHLVSPQMAAAAAIAGHFVDIREWK
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
gtgagcacaccgaagaccatcatccagaagatctgggagcagcacgtcgtggcgagcgag
ccggggaagcccgacctgctcttcatcgacctccatctcgtgcacgaagtgacgtcgccg
caggcgttcgaagggctgcggctggccggccggcgggtgcggcacccggagctgacgctg
gcgacggtcgaccacaacgtgccgaccatcgaccgggacaagccgtggtcggacccgctt
tcggtgcagcaggtggaggcgctgcggaagaactgcgaggagttcggcatcccgctgttt
ggggtgggggacatccggcaggggatcgtgcacgtgatcgggccggagcaggggctgacg
cagccggggatgacgatcgtctgcggggacagccacacctcgacgcacggggcgttcggc
gcgctcgccttcggcatcggcacgagcgaggtggagcacgtgctcgcgacgcagacgctg
ccgcaggcgaagccgaagacgatgtcggtggaggtgaccggcgagctgcacccgggtgtg
acggcgaaggacgtgatcctcgggatcatcgccaagatcggcgtctcgggcggcgtcggg
cacgtcatcgaataccggggcgaggtcatccggaacctttcgatggaagggcggatgacc
atttgcaacatgtcgatcgaaggcggggcgcgggccgggctgatcgcgcccgatgacacg
acgtttgcctacatggaagggcggcggttcgcgccgaagggggctgactgggagcgggcg
ctggactactggcggtcgctgccgaccgacgaaggggcagaattcgacacgtacgtgacg
ctcgacggtgcggagatcgtgccgacggtgacgtgggggacgacgccggcgcagagcgtg
ccggtgacgggccgggtgccggacccctcggaggccccgacgccgcaggcgcgggagctg
gcggagcgcgcgctgcactacatggggctggagccgggcacgccgatccaggagatccgg
ctggaccgggtgttcatcgggtcgtgcacgaacagccggatcgaagacctgcgggctgcg
gcggaggtggtgcggggccggaaggtcgcgccgcacgtgcgggcgatggtggtgccgggc
tccgggctggtgaagcaccaggcggaggaggaggggctcgaccgcatcttcaaagaggcg
gggttcgagtggcgggaggccggctgctcgatgtgcctcgggatgaacccggacatcctg
atgccgggcgagcgctgcgcgagcacctcgaaccggaacttcgagggccggcagggccgc
gggggccggacgcacctcgtgagcccgcagatggcggccgcggcggcgatcgcagggcat
ttcgtcgacatccgggagtggaagtag
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