Trachypithecus francoisi (Francois's langur): 117073985
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Entry
117073985 CDS
T07225
Symbol
DOT1L
Name
(RefSeq) LOW QUALITY PROTEIN: histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
tfn
Trachypithecus francoisi (Francois's langur)
Pathway
tfn00310
Lysine degradation
tfn01100
Metabolic pathways
tfn05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
tfn00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
117073985 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
117073985 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
tfn03036
]
117073985 (DOT1L)
Enzymes [BR:
tfn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
117073985 (DOT1L)
Chromosome and associated proteins [BR:
tfn03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
117073985 (DOT1L)
HMT complexes
Dot1-containing complex
117073985 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
117073985
NCBI-ProteinID:
XP_033051061
LinkDB
All DBs
Position
Unknown
AA seq
1732 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRESKSNAATPTKGP
EGKLAGPTDAPMDSGAEEEKAGAATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSTA
NPERKPKKNQTALDVLHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNTQLLGAAQQLLSHCQAQK
EEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRSQSLQLL
KARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDTLSLHLRGKGALGRELEPDAGRLHLELDCAKFSLPHLSSMSPELSMNGQAAGY
ELCSXLSRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLAAPDYTRLSPAKIV
LRRHLSQDHTVPSRPAASELHPRAEHTKENGLPYQSPSVPGSLKLSPQDPRPLSPGALQL
AGEKSSEKGLRERTYGSGGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARST
PSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGV
ELATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPL
TEASKGDLPSDSGFSDPESEAKRRIVFTIATGAGSAKQSPSSKHSPLTASARGDCVPSHG
QDSRKRGRRKRASTGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVNNINQPLEI
TAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARI
ERKIATISLESKSPPKTLENGGGLAGRKPTPASEPVNNSKWKSTFSPISDIGLAKSADSP
LQASSALSQNSLFTFRPALEEPPADAKLATHPRKGFPGSLSGTDGLSPSTNPANGCTFGG
GLAADLSLHSFSDGASLPHKGPEAASLSSPLSFPSQRGKEASDANPFLSKRQLDGLAGLK
GEGSRSKEAGEGGLQLCGPTDKTPLLTGKAAKARDRELDLKNGHNLFISAAAVPPGSLLS
GPGLAPVASSAGGAASSTQTHRPFLGPFPPGPQFALGPMSLQANLGSVAGSSVLQSLFSS
VPAAAGLVHVSSAATRLTNSHAMGSFSGVAGSTVGGVFNHAVPSASAHPFGARVGRGAAC
GSATLGPSPLQAAASSFQAPASVETRPPPPPPPPPLPPPAHLGRPPAGPPVLHAPPPPNA
ALPPPPTLLASNPEPALLQSLASLPPNQAFLPPTSAASLPPANASLSIKLTSLPHKGARP
SFTVHHQPLPRLALAQAAPGIPQASATGPSAVWVSLGMPPPYAAHLSGVKPR
NT seq
5199 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgagactcaagtcgcccgtgggggctgagcccgccgtctac
ccgtggccgttgccggtctacgacaaacatcacgatgctgctcatgaaatcatcgagacc
atccgatgggtctgtgaagaaatcccggatctcaagctcgctatggagaattacgtttta
attgactatgacaccaaaagcttcgagagcatgcagaggctctgcgacaagtacaaccgc
gccatcgatagcatccaccagctgtggaagggcaccacgcagcccatgaagctgaacacg
cggccgtccaccgggctcctgcgccatatcctgcagcaggtctacaaccactcggtgact
gaccccgagaagctcaacaactacgagcccttctccccggaggtgtacggggagacctcc
ttcgacctggtggcccaaatgatcgacgagatcaagatgaccgacgacgacctgtttgtg
gacttggggagcggtgtgggccaggtcgtgctccaggttgccgctgccaccaactgcaaa
catcactatggcgtcgagaaagcagacatcccggccaagtatgcggagaccatggaccgc
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacattggagaga
ggcgatttcctctcagaagagtggagggagcgaatcgccaacacgagtgttatatttgtg
aataattttgcctttggtcctgaggtggatcaccagctgaaggagcggtttgcaaacatg
aaggaaggtggcagaatcgtgtcctcgaaaccctttgcacctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctgtcgcccctgaag
ggctcggtgtcgtggacagggaagccagtctcctactacctgcacactatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaacccaaaactcagggaggaacaggaggca
gcccggcgccgccagcagcgcgagagcaagagcaacgcggccacgcccaccaagggcccc
gagggcaagctggccggccccactgacgcccccatggactctggtgctgaggaagagaag
gcaggagcagccaccgtgaagaagccgtctccctccaaagcccgcaagaagaagctcaac
aagaaggggaggaagatggctggccgcaagcgcgggcgccccaagaagatgagcactgcg
aaccccgagcggaagcccaagaagaaccaaactgcactggatgtcctgcacgctcagacc
gtgtctcagacggcagcctcctcaccccaggatgcctacaggtcccctcacagcccgttc
taccagctacctccgagcgtgcagcggcactcccccaacccgctgctggtggcgcccacc
ccgcccgcgttgcagaagctgctagagtctttcaagatccagtatctgcagttcctggca
tacacaaagaccccccagtacaaggccagcctacaggagctgctgggccaggagaaggag
aagaacacccagctcctgggcgcggctcagcagctcctcagccactgccaggcccagaag
gaggagatcaggaggctgttccagcaaaaattggatgagctgggcgtgaaggcgctgacc
tacaacgacctgattcaggcgcagaaggagatctccgcccacaaccagcagctgcgggag
cagtcagagcagctggagcaggacaaccgtgcgctgcgcagccagagcttgcagctgctc
aaggctcgctgtgaggagctgcagctggactgggccacactgtccctggagaagctgctg
aaggagaagcaggccctgaagagccagatctcggagaagcagaggcactgcctggagctg
cagatcagcatcgtggagctggagaagagccagcggcagcaggagctcctgcagctcaag
tcctgtgtgccgcctgatgacaccctgtctctgcacctacgcgggaagggtgccctgggc
cgcgagctggagcctgacgccggccggctgcacctggagctggactgcgccaagttctcg
ctgcctcacttgagcagcatgagcccagagctctccatgaacggccaggctgccggctat
gagctctgcagtnggctgagccggccgtcgtccaagcagaacacaccccagtacctggcc
tcacccctagaccaggaggtggtgccctgcacccccagccacagcggccggccacgcctg
gagaagctgtctggcctggctgcacccgactacaccaggctgtccccggccaagattgtg
ctgaggcggcatctgagccaggaccacacggtgcccagcaggccggccgccagtgagctg
cacccaagagctgagcacaccaaggagaacggccttccctaccagagccccagcgtgcct
ggcagccttaagctgagtccccaggacccgcggcccctgtcacctggggccttgcagctt
gctggagagaagagcagtgagaagggcctgagagagcgcacctacggcagcggcggggag
ctcatcaccagcctgcccatcagcatcccgctcagcaccgtgcagcccaacaagctcccg
gtcagcatccccctggccagcgtggtgctgcccagccgcgctgagagggcgaggagcacc
cccagtcccgtgctgcagccccgcgacccctcatccacacttgaaaagcagattggtgct
aatgcccacggtgctgggagcagaagccttgccctggcccccgcaggcttctcctatgct
ggctctgtggccatcagcggggccttggcgggcagcccggcctctctcacacctggagtc
gagctggccaccttggatgagtcctccagctctgggagcctttttgccactgtggggtcc
cgcagctccacaccacagcaccccctgctgctggcacagccccggaactcgctcccggcc
tctcccgcccaccagctctcctccagcccccggcttggtggggctgcccagggcccgctc
accgaggccagcaagggggacttgccctcagattccggtttctcagatcctgagagtgag
gccaagaggaggatcgtgttcaccatcgccactggtgcgggcagtgccaaacagtcgccc
tccagcaagcacagccccctgaccgccagcgcccgtggggactgtgtgccgagccacggg
caggacagccgcaagcgcgggcggcggaagcgagcatcgacagggacgcccagcttgagc
gcgggcgtgtcccccaagcgccgagccctgccgtccgtcgctggccttttcacacaacct
tcagggtctcccctcaacctcaactccatggtcaataacatcaaccagcccctggagatt
acagccatctcgtcccctgagacctccctgaagagctcccctgtgccctaccaggaccac
gaccagccccccgtgctcaagaaggagcggcctctgagccagaccaatggggcacactac
tccccgctcacctcggacgaggagccaggctctgaggacgagcccagcagcgcccgaatt
gagagaaaaattgcaacaatctccttagaaagcaaatctcccccgaaaaccttggaaaat
ggtggtggtttggcgggaaggaagcccacgcccgcgagcgagccagtcaacaacagcaag
tggaagtcgactttctcgcccatctctgacatcggcctggccaagtctgcagacagcccg
ctgcaggccagctccgccctcagccagaactccctgttcacgttccggcccgccctggag
gagccccctgccgatgccaagctggccacccaccccaggaaaggctttcccggctctctg
tcggggactgacggactcagcccgagcaccaaccctgccaacggctgcacctttggcggg
ggcctggccgcggacctgagtttacacagcttcagcgatggtgcttctcttccccacaag
ggccccgaggcggccagcctgagctccccgctgagcttcccctcgcagcgtggcaaggag
gcctcggacgccaacccttttctgagcaagaggcagctggacggcctggctgggctgaag
ggcgagggcagccgcagcaaggaggcaggggagggcggcctgcagctgtgcgggcccacg
gacaagaccccgctgctgaccggcaaggccgccaaggcccgagaccgcgagctcgacctc
aagaatggccacaacctcttcatctccgctgcggccgtgcctcccggaagcctcctcagc
ggccccggcctggccccggtggcgtcctccgcaggcggcgcggcgtcctccacccagacg
caccggcccttcttgggccccttcccgccgggaccgcagtttgcgctcggccccatgtcc
ctgcaggccaacctcggctccgtggccggctcctccgtgctgcagtcgctgttcagctct
gtgccggccgccgcaggcctggtgcacgtgtcgtccgctgccaccagactgaccaactcg
cacgccatgggcagcttttccggggtggcaggcagcacagttggaggtgtctttaaccac
gcggtgccttccgcctctgctcatccgtttggagcccgtgtcggccgcggggctgcatgt
ggcagtgccacgctgggcccgagcccgctgcaggcggcggcctcttcctttcaggccccg
gcctcggttgagacccggccgccccctccgcctccgcctcccccgctgcccccgcctgcg
cacctgggccggccccccgcggggccgcccgtcctccacgccccgcctccacctaacgcc
gccttgcctcctcccccaacgctgctggcctctaaccctgagcccgcgcttctgcagagc
ctcgcgtccctcccgcctaaccaagctttcttgccccccacctctgctgcctctctgccg
cctgctaacgcctctttgtctatcaagctcacctccctcccgcacaagggcgcccgcccc
tccttcacggtgcaccaccagcccctgccccggctggccctggcccaggccgcgcccggg
atcccgcaggccagcgccacggggccgtccgcggtgtgggtgtccctcggcatgccgcct
ccctatgccgcgcacctttcgggggttaagccgcgataa
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integrated database retrieval system
