Trachypithecus francoisi (Francois's langur): 117076717
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Entry
117076717 CDS
T07225
Symbol
INSR
Name
(RefSeq) insulin receptor isoform X1
KO
K04527
insulin receptor [EC:
2.7.10.1
]
Organism
tfn
Trachypithecus francoisi (Francois's langur)
Pathway
tfn04010
MAPK signaling pathway
tfn04014
Ras signaling pathway
tfn04015
Rap1 signaling pathway
tfn04022
cGMP-PKG signaling pathway
tfn04066
HIF-1 signaling pathway
tfn04068
FoxO signaling pathway
tfn04072
Phospholipase D signaling pathway
tfn04150
mTOR signaling pathway
tfn04151
PI3K-Akt signaling pathway
tfn04152
AMPK signaling pathway
tfn04211
Longevity regulating pathway
tfn04213
Longevity regulating pathway - multiple species
tfn04520
Adherens junction
tfn04910
Insulin signaling pathway
tfn04913
Ovarian steroidogenesis
tfn04923
Regulation of lipolysis in adipocytes
tfn04930
Type II diabetes mellitus
tfn04931
Insulin resistance
tfn04932
Non-alcoholic fatty liver disease
tfn04960
Aldosterone-regulated sodium reabsorption
tfn05010
Alzheimer disease
tfn05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
tfn00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
117076717 (INSR)
04014 Ras signaling pathway
117076717 (INSR)
04015 Rap1 signaling pathway
117076717 (INSR)
04066 HIF-1 signaling pathway
117076717 (INSR)
04068 FoxO signaling pathway
117076717 (INSR)
04072 Phospholipase D signaling pathway
117076717 (INSR)
04022 cGMP-PKG signaling pathway
117076717 (INSR)
04151 PI3K-Akt signaling pathway
117076717 (INSR)
04152 AMPK signaling pathway
117076717 (INSR)
04150 mTOR signaling pathway
117076717 (INSR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
117076717 (INSR)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
117076717 (INSR)
04923 Regulation of lipolysis in adipocytes
117076717 (INSR)
04913 Ovarian steroidogenesis
117076717 (INSR)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
117076717 (INSR)
09149 Aging
04211 Longevity regulating pathway
117076717 (INSR)
04213 Longevity regulating pathway - multiple species
117076717 (INSR)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
117076717 (INSR)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
117076717 (INSR)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
117076717 (INSR)
04932 Non-alcoholic fatty liver disease
117076717 (INSR)
04931 Insulin resistance
117076717 (INSR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tfn01001
]
117076717 (INSR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
tfn04090
]
117076717 (INSR)
Enzymes [BR:
tfn01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
117076717 (INSR)
Protein kinases [BR:
tfn01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
117076717 (INSR)
CD molecules [BR:
tfn04090
]
Proteins
117076717 (INSR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
Insulin_TMD
fn3
Kinase-like
DUF4476
B2
Motif
Other DBs
NCBI-GeneID:
117076717
NCBI-ProteinID:
XP_033056418
LinkDB
All DBs
Position
Unknown
AA seq
1382 aa
AA seq
DB search
MGTGGRRGTAAAPLLVAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL
GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQG
CHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC
TVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL
EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE
RNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE
RQAEDSELFELDYCLKGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGECCSCPKTDSQIL
KELEESSFRKTFEDYLHNVVFVPRKTSSGTGAEDRRPSRKRRSLGDVGNVTAAVPTVAAF
PNTSSTSTPTSPEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYV
SARTMPEAKADDIVGPVTHEIFENNIVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCV
SRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIG
PLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR
EKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKG
FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA
AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV
RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN
CPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENKAPESEELEME
FEDMENVPLDRSSHCQREEAGGRDGGSSLGFKRSYEEHIPYTHMNGGKKNGRILTLPRSN
PS
NT seq
4149 nt
NT seq
+upstream
nt +downstream
nt
atgggcaccgggggccggcgggggacagctgccgcgccgctgctggtggcggtggccgcg
ctgctattgggcgccgcgggccacctgtaccccggagaggtgtgtcccggcatggatatc
cggaacaacctcaccaggttacacgagctggagaattgctctgtcatcgaaggacacttg
cagatactcttgatgttcaaaacgaggcccgaagatttccgagacctcagtttccccaaa
ctcataatgatcactgattacttgctgctcttccgggtctatgggcttgagagcctgaag
gacctgttccccaacctcacggtcatccggggatcacgactgttctttaactacgcgcta
gtcatcttcgagatggttcacctcaaggaactcggcctctacaacctaatgaacattacc
cggggttctgtccgcattgagaagaacaacgagctctgttacttggccactatcgactgg
tcccgcatcctggattccgtggaggataattacatcgtgttgaacaaagatgacaacgag
gagtgtggagacatctgtccgggtacagcgaagggcaagaccaactgccccgccaccgtc
atcaatgggcagtttgtcgaacggtgttggactcatagtcactgccagaaagtttgccca
accatctgtaagtcacacggctgcactgccgaaggcctctgttgccacagcgagtgcctg
ggcaactgttctgagcccgacgaccccaccaagtgcgtggcctgccgcaacttctacctg
gacggcaggtgtgtggagacctgcccgcccccgtactaccacttccaggactggcgctgt
gtgaacttcagcttctgccaggacctgcaccacaaatgcaagaactcgcggaggcagggc
tgccaccagtacgtcattcataacaacaagtgcatccctgagtgtccctccgggtacacg
atgaattccagcaacttgctgtgcaccccgtgcctgggcccctgtcccaaggtatgccac
ctcctagaaggcgagaagaccatcgactcggtgacgtctgcccaggagctccgaggatgc
actgtcatcaacgggagtctgatcatcaacattcgaggaggcaataatctggcagctgag
ctagaagccaacctcggcctcattgaagaaatttcagggtatctaaaaatccgccgatcc
tacgctctggtgtcactttccttcttccggaagttacgtctgattcgaggagagaccttg
gaaatcgggaactactccttctatgccttggacaaccagaacctaaggcagctctgggat
tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactataaccccaaa
ctctgcttgtcagaaatccacaagatggaagaagtttcaggaaccaaggggcgccaggag
agaaatgacattgccctgaagaccaatggggaccaggcatcctgtgaaaatgagttactt
aaattttcttacattcggacatctttcgataagatcttgctgagatgggagccgtactgg
ccccccgacttccgagacctcctggggttcatgctgttctacaaagaggccccttaccag
aatgtgacggagtttgacgggcaggatgcgtgtggttccaacagttggacggtggtagac
attgacccgcccctgaggtccaacgaccccaaatcacagaaccacccaggatggctaatg
cggggtctcaagccctggacccagtatgccatctttgtgaagaccctggtcaccttttcg
gatgaacgccggacctacggggccaagagtgacatcatttatgtccagacagatgctacc
aacccctccgtgcccctggatccaatctcagtatctaactcatcatcccagattattttg
aagtggaaacccccctccgaccccaacggcaacatcacccactacctggttttctgggag
aggcaggcggaagacagtgagctgttcgagctggattattgcctcaaagggctgaagctg
ccctccaggacctggtctccaccattcgagtctgaagattctcagaagcacaaccagagt
gaatatgaggattcagccggtgaatgttgctcctgtccaaagacagactctcagatcctg
aaggagctggaggagtcctcgtttcggaagacgtttgaggattacctgcacaacgtggtt
ttcgtccccagaaaaacctcttcaggcactggtgccgaggaccgtaggccatctcggaaa
cgcaggtcccttggcgatgttgggaatgtgacggcggccgtgcccacggtggcagctttc
cccaacacttcctcgaccagcacgcccacgagtccggaggagcacaggccctttgagaag
gtggtgaacaaggagtcgctggtcatctccggcttgcgacacttcacgggctatcgcatc
gagctgcaggcttgcaaccaagacacccctgaggaacggtgcagtgtggcagcctacgtc
agcgccaggaccatgcctgaagccaaggctgatgacattgttggccctgtgacacacgaa
atctttgagaacaacatcgtccacttgatgtggcaggagccgaaggagcccaatggtctg
atcgtgctgtatgaagtgagttatcggcgatatggcgatgaggagctgcatctctgtgtc
tcccgcaagcacttcgctctggaacggggctgcaggctgcgcgggctgtcgccggggaac
tacagcgtgcgagtccgggccacctccctggcgggcaacggctcctggacggaacccacc
tatttctacgtcacagactatttagatgtcccgtcaaatattgcaaaaattatcatcggt
cctctcatctttgtctttctcttcagtgttgtgattggaagtatttatctattcctgaga
aagaggcagccagatgggccactgggaccgctttacgcttcttcaaaccctgagtatctc
agtgccagtgatgtgtttccatgctctgtgtacgtgccggacgagtgggaggtgcctcga
gagaagatcaccctccttcgagagctggggcagggctcctttggcatggtgtatgagggc
aacgccagggacatcatcaagggtgaggcagagacccgcgtggcagtgaagacggtcaac
gagtcagccagtctccgagagcggattgagttcctcaatgaggcctcggtcatgaagggc
ttcacctgccatcatgtggtacgcctcctgggagtggtgtccaagggccagcccacgctg
gtggtgatggagctgatggctcacggagacctgaagagctacctccgttctctgcggcca
gaggctgagaataatcctggccgccctccccctaccctgcaagagatgattcagatggca
gcagagattgctgatgggatggcctacctgaatgccaagaagtttgtgcatcgggacctg
gcagcaagaaactgcatggtcgcccatgattttactgtcaaaattggagactttggaatg
accagggacatctatgaaacggattactaccggaaagggggcaagggtctgctgcctgtg
cggtggatggcgccggagtccctgaaggatggggtcttcaccacttcttctgacatgtgg
tcctttggcgtggtcctttgggaaatcaccagcttggcagaacagccttaccaaggcctg
tctaatgaacaggtgttgaaatttgtcatggacggagggtatctggatcaacctgacaac
tgtccagagagagtcactgacctcatgcgcatgtgctggcaattcaaccccaagatgagg
ccaaccttcctggagattgtcaacctgctcaaagacgacctgcaccccagctttccagag
gtgtccttctttcacagcgaggagaacaaggcccccgagagtgaggagctggagatggag
tttgaggacatggagaatgtgccgctggaccgttcctcgcactgtcagagggaggaggcg
gggggccgggatggagggtcctcgctaggtttcaagcggagctacgaggaacacatccct
tacactcacatgaacggaggcaagaaaaacgggcggatcctgaccttgcctcggtccaat
ccttcctaa
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integrated database retrieval system
