Thermobifida fusca: Tfu_2731
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Entry
Tfu_2731 CDS
T00265
Name
(GenBank) uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
tfu
Thermobifida fusca
Pathway
tfu00860
Porphyrin metabolism
tfu01100
Metabolic pathways
tfu01110
Biosynthesis of secondary metabolites
tfu01120
Microbial metabolism in diverse environments
tfu01240
Biosynthesis of cofactors
Module
tfu_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
tfu_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
tfu_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
tfu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Tfu_2731
Enzymes [BR:
tfu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Tfu_2731
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Tfu_2731
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AAZ56764
UniProt:
Q47LA8
LinkDB
All DBs
Position
complement(3210163..3211854)
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AA seq
563 aa
AA seq
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MNPQTETPATGAEHAAKPAAGHIALVGAGPGDAELLTLRGAALLGQADVVLTFREPPHLA
RHRKGLLSHCRPDTVIVDPDEYGDSGDAFALSKAAQGLRVVRLYPGDPLLSGQGAALAEA
ASDAGIEFEIVPGLSSITAVPAYAGTELLPHGTNEVRILDAADTDVDWVNAAQSKATLVV
LHPDAPTEDDPDAKGPGLDRICKTLIAGGRPDTTPVTVTRMGTTTYQTTITSTLARLAAD
LKAADAKGHTIPRPSLLIVGEGVAQRQKKLSWFETKPLFGWRVLVPRTRQQAPALSEQLR
SYGAVPEEVPTISVEPPRTPQQMERAVRGLVTGRYQWVAFTSVNAVKAIRERIEDYGLDA
RAFAGVKVAAVGEQTAAALRAFGIHPDLQPPEDKQSAAGLVEVWPPYDPDIDPIERVLLP
RADIATEVLSEGLVNLGWEVDDVTAYRTVRAAPPPAPIREAIKGGGFDAVMFTSSSTVRN
LVGIAGKPHATTVIAVIGPETAKTAEEFGLRVDVRAPKASVAALAEALAEFGAAQRQAAI
EAGKPVLRPSQKRRGRRRKNLMI
NT seq
1692 nt
NT seq
+upstream
nt +downstream
nt
gtgaacccgcagactgagaccccggctaccggggccgagcacgccgccaagcccgccgcc
ggtcacatcgcgctggtgggtgctggaccgggcgacgccgagctgctgacactgcggggc
gccgcgctgctgggtcaggccgacgtcgtcctcacgttccgtgaaccgccgcatcttgcc
cggcaccggaaagggctgctgagccactgccgccctgacacggtcatcgtcgacccggac
gagtacggggacagcggtgacgcgttcgcgctctccaaggctgcgcaaggactgcgtgtc
gtccgcctctacccgggcgacccgctgctgagcggccagggcgcggctcttgccgaggct
gccagcgacgcggggatcgagttcgagatcgtgccggggctctcctcgattaccgccgtc
cctgcctacgcgggaaccgagctgctgccgcacggcaccaacgaggtgcggatcctcgac
gctgccgacactgacgtggactgggtcaacgctgcgcagagcaaggcgaccctggtcgtg
ctccacccggatgcgcccaccgaggacgatccggacgcgaaaggccccggcctcgaccgg
atctgcaagaccttgatcgccggcggtcggcccgacaccacaccggtcacggtgacccgg
atggggacgaccacctaccagaccactatcacctcaaccctggcccggctggcggccgat
ctgaaagccgccgacgccaaggggcacaccatcccccgtccgtcgctgctcatcgtcggg
gaaggggtggcgcagcgccagaagaagctgtcctggttcgaaaccaagcccttgttcggc
tggcgggtcctggtgccgcgcacccgccagcaggccccggccctctccgagcagttgcgc
agctacggcgcggtacccgaggaggtgccgacgatctcggtggagccgccgcgcacaccg
cagcagatggagcgggcggtccgcggcctggtcaccggacgctaccagtgggtggcgttc
acctcggtgaacgcggtcaaagccatccgggagcgtatcgaagactacggtttggatgcg
cgggctttcgccggggtgaaagtcgccgcggtcggggagcagaccgcggccgcgctccgc
gccttcggcatccacccggacctgcagccgccggaggacaagcagtccgcggccgggctc
gttgaagtgtggccgccctacgacccggatatcgacccgatcgagcgggtcctgctgccc
cgcgccgacatcgccaccgaggtcctctccgaaggcttggtgaacctcggctgggaggtc
gacgacgtcaccgcctaccggacggtgcgggccgcacccccgcccgcacctatccgcgaa
gccatcaagggcggcgggttcgacgcggtgatgttcacctcgtcctccacggtccgcaac
ctcgtcgggatcgcgggcaagccgcacgccaccaccgtgatcgccgtgatcgggccggag
accgcgaaaaccgcggaagagttcggcctgcgtgtcgacgtccgcgcgccgaaggcgtcg
gtggcagcgctggccgaagcgctcgcagagttcggtgccgcccagcggcaggcggcgatc
gaagcgggcaagcccgtgctgcggcccagccagaagcgccgggggcgtcgccgtaagaac
ctcatgatctga
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