Theropithecus gelada (gelada): 112612802
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Entry
112612802 CDS
T08041
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge00310
Lysine degradation
tge01100
Metabolic pathways
tge05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
112612802 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
112612802 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
tge03036
]
112612802 (DOT1L)
Enzymes [BR:
tge01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
112612802 (DOT1L)
Chromosome and associated proteins [BR:
tge03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
112612802 (DOT1L)
HMT complexes
Dot1-containing complex
112612802 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
112612802
NCBI-ProteinID:
XP_025223512
Ensembl:
ENSTGEG00000012698
LinkDB
All DBs
Position
19:2105701..2167810
Genome browser
AA seq
1728 aa
AA seq
DB search
MLLLLLLLLLVWGLGVALLERPWDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYD
TKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVTDPEK
LNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCKHHYG
VEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFA
FGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVS
WTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRESKSNAATPTKGPEGKL
AGPTDAPMDSGAEEEKAGAATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSTANPER
KPKKNQTALDVLHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPTPPAL
QKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNTQLLGAAQQLLSHCQAQKEEIR
RLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRSQSLQLLKARC
EELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVP
PDDALSLHLRGKGALGRELEPDASRLHLELDCAKFSLPHLSSMSPELSMNGQAAGYELCS
ALSRPSSKQNTPQYLASPLDQEVVPCTPSHGGRPRLEKLSGLAAPDYTRLSPAKIVLRRH
LSQDHTVPGRPAASELHPRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQLAGEK
SSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPV
LQPRDPSSTLEKQIGANAHSAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGAEPAT
LDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPLPEAS
KGDLPLDSGFSDPESEAKRRIVFTIAAGAGSARQSPSSKHSPLTASARGDCVPSHGQDSR
KRGRRKRASTGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEITAIS
SPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARIERKI
ATISLESKSPPKTLENGGGLAGRKPMPASEPVNNSKWKSTFSPISDIGLAKSADSPLQAS
SALSQNSLFTFRPALEEPPADAKLATHPRKGFPGSLSGADGLSPSTNPANGCTFGGGLAA
DLSLHSFSDGASLPHKGPEATGLSSPLSFPSQRGKEASDANPFLSKRQLDGLAGLKGEGS
RSKEAGEGGLQLCGPTDKTPLLTGKAAKARDRELDLKNGHNLFISAAAVPPGSLLSGPGL
APVASSAGGAASSTQTHRPFLGPFPPGPQFALGPMSLQANLGSVAGSSVLQSLFSSVPAA
AGLVHVSSAATRLTNSHAMGSFSGVAGSTVGGVFNHAVPSASAHPFGARVGRGAACGSAT
LGPSPLQAAASSFQAPASVETRPPPPPPPPPLPPPAHLGRPPAGPPVLHAPPPPNAALPP
PPTLLASNPEPALLQSLASLPPNQAFLPPTSAASLPPANASLSIKLTSLPHKGARPSFTV
HHQPLPRLALAQAAPGIPQASATGPSAVWVSLGMPPPYAAHLSGVKPR
NT seq
5187 nt
NT seq
+upstream
nt +downstream
nt
atgctgttgctgctcctgttgctgctcctcgtctggggcttaggggtggccttgctggag
aggccatgggacaaacatcacgatgctgctcatgaaatcatcgagaccatccgatgggtc
tgtgaagaaatcccggatctcaagctcgctatggagaattacgttttaattgactatgac
accaaaagcttcgagagcatgcagaggctctgcgacaagtacaaccgcgccatcgatagc
atccaccaactgtggaagggcaccacgcagcccatgaagctgaacacgcggccgtccact
gggcttctgcgccacatcctgcagcaggtctacaaccactcagtgactgaccccgagaag
ctcaacaactacgagcccttctcccctgaggtgtacggggagacctccttcgacctggtg
gcccagatgatcgacgagatcaagatgaccgacgacgacctgtttgtggacttggggagc
ggtgtgggccaggttgtgctccaggtcgccgctgccaccaactgcaaacatcactatggc
gtcgagaaagcggacatcccggccaagtatgcggagaccatggaccgcgagttcaggaag
tggatgaaatggtatggaaaaaagcatgcagaatacacattggagagaggcgatttcctc
tcagaagagtggagggagcgaatcgccaacacgagtgttatatttgtgaataattttgcc
tttggtcctgaggtggatcaccagctgaaggagcggtttgcaaacatgaaggaaggtggc
agaatcgtgtcctcgaaaccctttgcacctctgaacttcagaataaacagtagaaacttg
agtgacatcggcaccatcatgcgcgtggtggagctgtcgcctctgaagggctcagtgtca
tggacggggaagccagtctcctactacctgcacactatcgaccgcaccatacttgaaaac
tatttttctagtctgaaaaacccaaaactcagggaggaacaggaggcagcccggcgccgc
cagcagcgcgagagcaagagcaacgcggccacgcccaccaagggccccgagggcaagctg
gctggccccaccgacgcccccatggactctggtgctgaggaagagaaggcgggagcagcc
accgtgaagaagccatctccctccaaagcccgcaagaagaagctcaacaagaaggggagg
aagatggctggccgcaagcgcgggcgccccaagaagatgagcactgcgaaccccgagcgg
aagcccaagaagaaccaaactgcactggatgtcctgcacgctcagaccgtgtctcagacg
gcagcctcctcgccccaggatgcctacaggtcccctcacagcccgttctaccagctacct
ccgagtgtgcagcgtcactcccccaacccgctgctggtggcgcccaccccgcccgcgttg
cagaagctgctagagtctttcaagatccagtacctgcagttcctggcatacacaaagacc
ccccagtacaaggccagcctacaggagctgctgggccaggagaaggagaagaacacccag
ctcctgggcgcggctcagcagctcctcagccactgccaggcccagaaggaggagatcagg
aggctgttccagcaaaaattggatgagctgggcgtgaaggcgctgacctacaacgacctg
attcaggcgcagaaggagatctccgcccacaaccagcagctgcgggagcagtcagagcag
ctggagcaggacaaccgtgcgctgcgcagccagagcttgcagctgctcaaggctcgctgc
gaggagctgcagctggactgggccacgctgtccctggagaagctgctgaaggagaagcag
gccctgaagagccagatctcagagaagcagaggcactgcctggagctgcagatcagcatc
gtggagctggagaagagccagcggcagcaggagctcctgcagctcaagtcctgtgtgccg
cctgatgacgccctgtctctgcacctgcgcgggaagggtgccctgggccgcgagctggag
cctgacgccagccggctgcacctggagctggactgcgccaagttctcgctgcctcacttg
agcagcatgagcccggagctctccatgaacggccaggctgccggctatgagctctgcagc
gcgctgagccggccctcgtccaagcagaacacgccccagtacctggcctcacccctcgac
caggaggtggtgccctgcacccccagccatggcggccggccgcgcctggagaagctgtct
ggcctggctgcacccgactacaccaggctgtccccggccaagattgtgctgaggcggcac
ctgagccaggaccacacggtgcccggcaggccggctgccagtgagctgcacccgagagct
gagcacaccaaggagaacggccttccctaccagagccccagcgtgcctggcagcatgaag
ctgagtccccaggacccgcggcccctgtcacctggggccttgcagcttgctggagagaag
agcagtgagaagggcctgagagagcgcgcctacggcagcagcggggagctcatcaccagc
ctgcccatcagcatcccgctcagcaccgtgcagcccaacaagctcccggtcagcatcccc
ctggccagcgtggtgctgcccagccgcgctgagagggcgaggagcacccccagtcccgtg
ctgcagccccgcgacccctcgtccacacttgaaaagcagattggtgctaatgcccacagc
gctgggagcagaagccttgccctggcccctgcaggcttctcctatgctggctcggtggcc
atcagcggggccttggcgggcagcccggcctccctcacacctggagccgagccggccacc
ttggatgagtcctccagctctgggagcctttttgccaccgtggggtcccgcagctccaca
ccacagcaccccctgctgctggcacagccccggaactcactcccggcctctcccgcccac
cagctctcctccagcccccggcttggtggggctgcccagggcccgctccccgaggccagc
aagggggacttgcccttagactccggtttctcagatcctgagagtgaggccaagaggagg
atcgtgttcaccatcgctgcgggcgcgggcagtgccagacagtcgccctccagcaagcac
agccccctgaccgccagcgcccgtggggactgcgtgccgagccacgggcaggacagccgc
aagcgtgggcggcggaagcgagcatcgacggggacgcccagcttgagcgcaggcgtgtcc
cccaagcgccgagccctgccgtccgtcgctggccttttcacacaaccttcggggtctccc
ctcaacctcaactccatggtcagtaacatcaaccagcccctggagattacagccatctcg
tcccctgagacctccctgaagagctcccctgtgccctaccaggaccatgaccagcccccc
gtgctcaagaaggagcggcctctgagccagaccaatggggcacactactccccgctcacc
tcggacgaggagccaggctctgaggatgagcccagcagcgcccgaattgagagaaaaatt
gcaacaatctccttagaaagcaaatctcccccgaaaaccttggaaaatggtggtggcttg
gcgggaaggaagcccatgcccgcgagcgagccagtcaacaacagcaagtggaagtctact
ttctcgcccatctccgacatcggcctggccaagtctgcagacagcccgctgcaggccagc
tccgcccttagccagaactccctgttcacgttccggcccgccctggaggagccccctgcc
gatgccaagctggccacccaccccaggaaaggctttcctggctctctgtcgggggctgac
ggactcagcccgagcaccaaccctgccaacggctgcacctttggtgggggcctggccgcg
gacctgagtttacacagcttcagcgatggtgcttctcttccccacaagggccccgaggcg
accggcctgagctccccactgagcttcccctcgcagcgtggcaaggaggcctcggacgcc
aaccctttcctgagcaagaggcagctggatggcctggctgggctgaagggcgagggcagc
cgcagcaaggaggcaggggagggcggcctgcagctgtgcgggcccacggacaagaccccg
ctgctgaccggcaaggccgccaaggcccgggaccgcgagctcgacctcaagaatggccac
aacctcttcatctccgctgcggctgtgcctcctggaagcctcctcagcggccccggcctg
gccccggtggcgtcctccgcaggcggcgcggcgtcctccacccagacgcaccggcccttc
ttgggccccttcccgccgggaccgcagttcgcgctcggccccatgtccctgcaggccaac
ctcggctccgtggccggctcctctgtgctgcagtcgctgttcagctctgtgccggccgcc
gcaggcctggtgcacgtgtcgtccgctgccaccagactgaccaactcgcacgccatgggc
agcttttccggggtggcaggcagcacagttggaggtgtctttaaccacgcggtgccttcc
gcctctgctcatccgtttggagcccgtgtcggccgcggggctgcatgtggcagcgccacg
ctgggcccgagcccgctgcaggcggcggcctcttcctttcaggccccggcctcggttgag
acccggccgccccctccgcctccgcctcccccgctgcccccgcctgcgcacctgggccgg
ccccccgcggggccgcccgtcctccacgccccgcctccacctaacgccgccttgcctcct
cccccaacgctgctggcctctaaccctgagcccgcgcttctgcagagcctcgcgtccctc
ccgcctaaccaagctttcttgccccccacctctgctgcctctctgccgcctgctaacgcc
tctttgtctatcaagctcacctccctcccgcacaagggcgcccgcccatccttcacggtg
caccaccagcccctgccccggctggccctggcccaggccgcgcccgggatcccgcaggcc
agcgccacggggccgtccgcggtgtgggtgtccctcggcatgccgcctccctatgccgcg
cacctttcgggggttaagccgcgataa
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integrated database retrieval system
