Theropithecus gelada (gelada): 112613164 Help Entry 112613164         CDS       T08041                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism tge  Theropithecus gelada (gelada) Pathway tge04010   MAPK signaling pathway tge04014   Ras signaling pathway tge04015   Rap1 signaling pathway tge04022   cGMP-PKG signaling pathway tge04066   HIF-1 signaling pathway tge04068   FoxO signaling pathway tge04072   Phospholipase D signaling pathway tge04150   mTOR signaling pathway tge04151   PI3K-Akt signaling pathway tge04152   AMPK signaling pathway tge04211   Longevity regulating pathway tge04213   Longevity regulating pathway - multiple species tge04520   Adherens junction tge04910   Insulin signaling pathway tge04913   Ovarian steroidogenesis tge04923   Regulation of lipolysis in adipocytes tge04930   Type II diabetes mellitus tge04931   Insulin resistance tge04932   Non-alcoholic fatty liver disease tge04960   Aldosterone-regulated sodium reabsorption tge05010   Alzheimer disease tge05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:tge00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     112613164 (INSR)    04014 Ras signaling pathway     112613164 (INSR)    04015 Rap1 signaling pathway     112613164 (INSR)    04066 HIF-1 signaling pathway     112613164 (INSR)    04068 FoxO signaling pathway     112613164 (INSR)    04072 Phospholipase D signaling pathway     112613164 (INSR)    04022 cGMP-PKG signaling pathway     112613164 (INSR)    04151 PI3K-Akt signaling pathway     112613164 (INSR)    04152 AMPK signaling pathway     112613164 (INSR)    04150 mTOR signaling pathway     112613164 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     112613164 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     112613164 (INSR)    04923 Regulation of lipolysis in adipocytes     112613164 (INSR)    04913 Ovarian steroidogenesis     112613164 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     112613164 (INSR)   09149 Aging    04211 Longevity regulating pathway     112613164 (INSR)    04213 Longevity regulating pathway - multiple species     112613164 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     112613164 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     112613164 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     112613164 (INSR)    04932 Non-alcoholic fatty liver disease     112613164 (INSR)    04931 Insulin resistance     112613164 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:tge01001]     112613164 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:tge04090]     112613164 (INSR) Enzymes [BR:tge01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      112613164 (INSR) Protein kinases [BR:tge01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    112613164 (INSR) CD molecules [BR:tge04090]  Proteins   112613164 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  112613164 NCBI-ProteinID:  XP_025224221 Ensembl:  ENSTGEG00000020791 LinkDB All DBs Position 19:complement(7128286..7317480) Genome browser AA seq 1388 aa AA seqDB search MKTQGPSFTSVRPALPLILLTHPPCVCSPVFAFCSFSLLVCPGMDIRNNLTRLHELENCS VIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRL FFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVL NKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLC CHSECLGNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCK NSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSA QELRGCTVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRL IRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSG TKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPPDFRDLLGFMLFY KEAPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVK TLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITH YLVFWERQAEDSELFELDYCLKGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGECCSCPK TDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGTGAEDPRPSRKRRSLGDVGNVTVAV PTVAAFPNISSTSTPTSPEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERC SVAAYVSARTMPEAKADDIVGPVTHEIFENNIVHLMWQEPKEPNGLIVLYEVSYRRYGDE ELHLCVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNI AKIIIGPLIFVFLFSIVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPD EWEVPREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNE ASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQ EMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGG KGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGY LDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENKAPEN EELEMEFEDMENVPLDRSSHCQREEAGGRDGGSSLGFKRSYEEHIPYTHMNGGKKNGRIL TLPRSNPS NT seq 4167 nt NT seq  +upstreamnt  +downstreamnt atgaaaacacagggcccaagtttcacgtccgtgaggccggctctgcccctgatccttctg acgcatccaccgtgcgtctgctcacctgtctttgctttctgttcattttctcttctagtg tgtcccggcatggatatccggaacaacctcaccaggttacacgagctggagaattgctct gtcatcgaaggacacttgcagatactcttgatgttcaaaacgaggcccgaagatttccgg gacctcagtttccccaaactcataatgatcactgattacttgctgctcttccgggtctat gggctcgagagcctgaaggacctgttccccaacctcacggtcatccggggatcacgactg ttctttaactacgcgctggtcatcttcgagatggttcacctcaaggaacttggcctctac aatctaatgaacatcacccggggttctgtccgcatcgagaagaacaacgagctctgttac ttggccactatcgactggtcccgcatcctggattccgtggaggataattacatcgtgttg aacaaagacgacaacgaggagtgtggagacatctgtccgggtacagcgaagggcaagacc aactgccccgccactgtcatcaatgggcagtttgtcgaacggtgttggactcatagtcac tgccagaaagtttgcccaaccatctgtaagtcacacggctgcactgccgaaggcctctgt tgccacagcgagtgcctgggcaactgttctgagcccgacgaccccaccaagtgcgtggcc tgccgcaacttctacctggacggcaggtgtgtggagacctgcccgcccccgtactaccac ttccaggactggcgctgtgtgaacttcagcttctgccaggacctgcaccacaaatgcaag aactcacggaggcagggctgccaccagtacgtcattcataacaacaagtgcatccctgag tgtccctccgggtacacgatgaattccagcaacttgctgtgcaccccgtgcctgggtccc tgtcccaaggtatgccacctcctagaaggcgagaagaccattgactcggtgacgtctgcc caggagctccgaggatgcaccgtcgtcaacgggagtctgatcatcaacattcgaggaggc aataatctggcagctgagctagaagccaacctcggcctcattgaagaaatttcaggttat ctaaaaatccgccgatcctacgctctggtgtcactttccttcttccggaagttacgtctg attcgaggagagacattggaaatcgggaactactccttctatgccttggacaaccagaac ctaaggcagctctgggactggagcaaacacaacctcaccatcactcaggggaaactcttc ttccactataaccccaaactctgcttgtcagaaatccacaagatggaagaagtttcagga accaaggggcgccaggagagaaatgacattgccctgaagacaaatggggaccaggcatcc tgtgaaaatgagttacttaaattttcttacattcggacatctttcgataagatcttgctg agatgggagccgtactggccccccgacttccgagacctcctggggttcatgctgttctac aaagaggccccttaccagaatgtgacggagtttgacgggcaggatgcgtgtggttccaac agttggacggtggtagacattgacccgcccctgaggtccaacgaccccaaatcacagaac cacccaggatggctaatgcggggtctcaagccctggacccagtatgccatctttgtgaag accctggtcaccttttcggatgaacgccggacctacggagccaagagcgacatcatttat gtccagacagatgccaccaacccctccgtgcccctggatccaatctcagtgtctaactca tcatcccagattattttgaagtggaaaccgccctccgaccccaatggcaacatcacccac tacctggttttctgggagaggcaggcggaagacagtgagctgttcgagctggattattgc ctcaaagggctgaagctgccctcgcggacctggtctccaccattcgagtctgaagattct cagaagcacaaccagagtgaatatgaggattcagccggtgaatgttgctcctgtccaaag acagactctcagatcctgaaggagctggaggagtcctcgtttaggaagacgtttgaggat tacctgcacaacgtggttttcgtccccagaaaaacctcttcaggcactggtgccgaggac cctaggccatctcggaaacgcaggtcccttggcgatgttgggaatgtgacggtggccgtg cccacggtggcagctttccccaacatttcctcgaccagcacgcccacgagtccggaggag cacaggccctttgagaaggtggtgaacaaggagtcgctggtcatctccggcttgcgacac ttcacgggctatcgcatcgagctgcaggcttgcaaccaagacacccctgaggagcggtgc agtgtggcagcctacgtcagcgccaggaccatgcctgaagccaaggctgatgacattgtt ggccctgtgacgcacgaaatctttgagaacaacatcgtccacttgatgtggcaggagccg aaggagcccaatggcctgatcgtgctgtatgaagtgagttatcggcgatatggcgatgag gagctgcatctctgtgtctcccgcaagcacttcgctctggaacggggctgcaggctgcgc gggctgtcgccggggaactacagcgtgcgagtccgggccacctccctcgcgggcaacggc tcctggacggagcccacctatttctacgtgacggactatttagatgtcccgtcaaatatt gcaaaaattatcatcggccccctcatctttgtctttctcttcagtattgtgattggaagt atttatctattcctgagaaagaggcagccagatgggcctctgggaccgctttacgcttct tcaaaccctgagtatctcagtgccagtgatgtgtttccatgctctgtgtacgtgccggac gagtgggaggtgcctcgagagaagatcaccctccttcgagagctggggcagggctccttc ggcatggtgtatgagggcaacgccagggacatcatcaagggtgaggcagagacccgcgtg gcagtgaagacggtcaacgagtcagccagtctccgagagcggattgagttcctcaatgag gcctcggtcatgaagggcttcacctgccatcatgtggtgcgtctcctgggagtggtgtcc aagggccagcccacgctggtggtgatggagctgatggctcacggagacctgaagagctac ctccgttctctgcggccagaggctgagaataatcctggccgccctccccctaccctgcaa gagatgattcagatggcggcggagattgctgacgggatggcctacctgaatgccaagaag ttcgtgcatcgggacctggcagcgagaaactgcatggtcgcccatgattttactgtcaaa atcggagactttggaatgaccagagacatctatgaaacggattactaccggaaaggaggc aagggtctgctccctgtacggtggatggcgccggagtccctgaaggatggggtctttacc acttcttctgacatgtggtcctttggcgtggtcctttgggaaatcaccagcttggcagaa cagccttaccaaggcctgtctaatgaacaggtgttgaaatttgtcatggacggagggtat ctggatcaacccgacaactgtccagagagagtcactgacctcatgcgcatgtgctggcaa ttcaaccccaagatgaggccaaccttcctggagatcgtcaacctgctcaaggacgacctg caccccagctttccggaggtgtcattctttcacagcgaggagaacaaggctcccgagaat gaggagctggagatggagtttgaggacatggagaacgtgcccctggaccgttcctcgcac tgtcagagggaggaggcggggggccgggatggagggtcctcgctgggtttcaagcggagc tacgaggaacacatcccttacacccacatgaacggaggcaagaaaaacgggcggattctg accttgcctcggtccaatccttcctaa

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