Thalassotalea sp. HSM 43: E2K93_04640
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Entry
E2K93_04640 CDS
T05926
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
tht
Thalassotalea sp. HSM 43
Pathway
tht00290
Valine, leucine and isoleucine biosynthesis
tht00660
C5-Branched dibasic acid metabolism
tht01100
Metabolic pathways
tht01110
Biosynthesis of secondary metabolites
tht01210
2-Oxocarboxylic acid metabolism
tht01230
Biosynthesis of amino acids
Module
tht_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tht00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
E2K93_04640 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
E2K93_04640 (leuC)
Enzymes [BR:
tht01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
E2K93_04640 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
E2K93_04640 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
QBY03711
UniProt:
A0A4P7JK37
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Position
1122999..1124396
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AA seq
465 aa
AA seq
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MMATTLYEKLWQRHLIEAVQGETPLIFVDRHLVHEVTSPQAFANLAFHNRPVHSPARTIA
TMDHNISTKSCDIDAAGENAANQLKTLEKNCQEFGIELYGMGHKNQGIVHVIGPELGLTL
PGQVIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLRQNKAKTMNIHVTGDVQHGIT
AKDIILAIIGAVGHAGATGYVVEYTGKAIRDLTMEERMTVCNMSIEFGAKAGLIAPDQTT
FDYLCDKEFAPKGGVWLEAVNDWQTLKTDADATFDHVVTIDAASIKPQVTWGTNPGQVAA
IDDVVPAPEQFSDPVERESCVNALSYMDLTPGTKISDISVNNVFIGSCTNSRIEDLRIAA
KVIAGKQVASGVTAIVVPGSYRVKQQAEQEGLAQIFTAAGFEWRLPGCSMCLGMNDDKLS
EGDRCASTSNRNFEGRQGRGARTHLVSPAMAAAAAVAGHFTEVSV
NT seq
1398 nt
NT seq
+upstream
nt +downstream
nt
atcatggctaccaccttgtatgaaaagttatggcagcgtcacttaattgaagctgttcaa
ggcgaaacaccgctaatttttgtcgaccgtcatttggtacacgaagttacctcaccgcaa
gcgtttgcaaacttagcgtttcataatcgccctgtgcacagtccggcgcgaaccattgcg
accatggatcacaacatttccacgaaaagctgtgacattgatgccgccggtgaaaatgct
gcaaaccagttaaagacgcttgagaaaaactgtcaagaatttggcatcgagctctatggt
atgggtcacaagaaccaaggtatcgttcatgttattggtcctgagcttggcctaacgttg
ccaggccaagtaatcgtatgtggtgattcgcataccgcgactcatggcgcattcggtgca
ttagcatttggtatcggtacctcggaagttgagcatgttttagcaacacaaaccttgcgt
caaaacaaagccaaaaccatgaacatccacgttaccggtgacgttcaacacggtattacc
gccaaggatattatcttagcgattattggcgcagttggtcacgctggtgcaacaggctat
gtggtggaatataccggcaaggcgattcgtgatttaaccatggaagagcgcatgacggta
tgtaatatgagtatcgaatttggcgccaaagcgggcttaatagcccctgaccaaaccacc
tttgattacttatgtgataaagaatttgccccgaaaggcggtgtttggttggaagcggtt
aatgattggcaaacattgaaaaccgatgccgatgcaacatttgatcatgttgtcacaatc
gatgctgccagcattaagccgcaagttacctggggcacaaaccctggccaagttgcagcg
attgatgatgtagtgccagcaccggagcaatttagcgatccggttgagcgtgaatcttgt
gttaacgcattaagctatatggatttaacgccaggcacaaaaatcagcgacatcagtgtt
aataacgtctttattggctcatgtactaactctcgcattgaagatttgcgaattgccgcc
aaagttattgccggaaaacaagtcgccagcggtgtcaccgccattgtcgtaccaggctct
tatcgagttaagcaacaagcagagcaagaaggactggcgcaaatattcactgccgcgggt
tttgaatggcgcttgccaggttgctcgatgtgtttgggtatgaacgatgacaaactaagc
gaaggtgatcgttgtgcttcaaccagcaaccgtaactttgaaggtcgtcaaggacgtggt
gctcgcacccatcttgttagcccagcgatggctgcagcggctgctgttgccggtcatttt
acagaagtcagtgtttag
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