Thermoflexus hugenholtzii: KNN16_06540
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Entry
KNN16_06540 CDS
T07254
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
thug
Thermoflexus hugenholtzii
Pathway
thug00290
Valine, leucine and isoleucine biosynthesis
thug00660
C5-Branched dibasic acid metabolism
thug01100
Metabolic pathways
thug01110
Biosynthesis of secondary metabolites
thug01210
2-Oxocarboxylic acid metabolism
thug01230
Biosynthesis of amino acids
Module
thug_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
thug00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
KNN16_06540
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
KNN16_06540
Enzymes [BR:
thug01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
KNN16_06540
4.2.1.35 (R)-2-methylmalate dehydratase
KNN16_06540
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
QWK11946
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Position
1439684..1441012
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AA seq
442 aa
AA seq
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MSGRTFAQKAIARAAGLPDAAVGQIVDVRPDLILSHDNTAAIAAMFYRLGLKRVRDPDRL
AITLDHAVPPPTPRHAQNHAEIRRFVAEQGIRNFFEAGRGICHQVLSEEALVLPGQMILG
ADSHTTHFGWMGAFGAGVGRSEVLALWATGEIWLRVPESIRIVLTGRLPPGVTTKDLCLR
IFRDLGADGGLYRSVEFAGEGVRHLSIESRMGIANFMAEFGVKNAYLPPDDRVFDWLAPR
RARRTGEPIEAVRERIAAGALYPDPDAPYEAEYVYCLEDLEPMVACPHSVDHVRPLREVA
GTRIDMAFIGTCTNGRLEDIAAAAEILRGRRIAPGVRLLVIPASREVLEEALRRGFIQTL
VEAGAMIGVPGCGPCMGNHMGIPAPGEIVISSGSRNFRGRMGTPDAEIYLASPAVVAASA
LRGVITDPREITSGKTDAQGAE
NT seq
1329 nt
NT seq
+upstream
nt +downstream
nt
atgagcgggcggaccttcgcccagaaggccatcgcccgggcggccgggctccccgatgcg
gccgtggggcagatcgtggacgtgcgccccgacctcatcctcagccacgacaacaccgcc
gccatcgcggccatgttctaccggctgggcctgaaaagggtgcgcgacccggaccgcctg
gccatcaccctggatcacgcggtgccgccccccaccccgcgccacgcccagaaccacgcg
gagatccgccgcttcgtggccgagcagggcatccggaacttcttcgaggccgggcggggg
atctgtcatcaggtgctgagcgaggaggccctggtcctccccggccagatgatcctgggc
gccgacagccacaccacccacttcggctggatgggcgccttcggggccggggtcgggcgc
agcgaggtgctggccctctgggccaccggggagatctggctgcgggtgccggaaagcatc
cgcatcgtcctgaccggccgcctgccccccggcgtgacgaccaaggacctgtgcctccgg
atcttccgcgatctgggggccgacggcgggctgtatcgctccgtggagttcgccggggaa
ggggtgcgccatctctccatcgagagccgcatggggatcgccaatttcatggccgagttc
ggagtcaagaacgcctacctcccccctgacgaccgcgtcttcgactggctggccccgcgc
cgggcccgacggaccggggagcccatcgaagcggtccgtgagcgcatcgccgccggagcc
ctgtatccggatccggacgcgccgtatgaggcggaatacgtctactgcctggaggatctg
gagccgatggtggcctgcccgcactccgtcgatcacgtgcgccccctccgggaggtcgcc
gggacccgcatcgacatggccttcatcggcacctgcaccaacgggcgcctggaagacatc
gcggcggcggcggagatcctgcgcggacggcggatcgccccgggcgtgcgcctgctggtc
atccccgcctcccgggaggtcctggaggaggccctgcggcggggcttcatccagaccctg
gtggaagcgggggcgatgatcggggttccgggctgcggcccgtgcatgggcaaccatatg
gggatcccggcccccggggagatcgtgatctcctccggcagccggaacttccgggggcgg
atggggacgccggacgcggagatctacctggccagcccggcggtggtggccgccagcgcc
ctgcggggggtgatcacggacccgcgggagatcacgtctggaaagaccgatgctcaagga
gctgaatga
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