Thermoanaerobacter italicus: Thit_0016
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Entry
Thit_0016 CDS
T01178
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
tit
Thermoanaerobacter italicus
Pathway
tit00290
Valine, leucine and isoleucine biosynthesis
tit00660
C5-Branched dibasic acid metabolism
tit01100
Metabolic pathways
tit01110
Biosynthesis of secondary metabolites
tit01210
2-Oxocarboxylic acid metabolism
tit01230
Biosynthesis of amino acids
Module
tit_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tit00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Thit_0016
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Thit_0016
Enzymes [BR:
tit01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
Thit_0016
4.2.1.35 (R)-2-methylmalate dehydratase
Thit_0016
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GFIT
Motif
Pfam:
Aconitase
AcnX
Cauli_VI
Motif
Other DBs
NCBI-ProteinID:
ADD01345
UniProt:
D3T544
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Position
18111..19367
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AA seq
418 aa
AA seq
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MGLTLTQKILSAKIGREVKAGELIEVDVDMVLGNDVTAPVAIREFEKIGKEEVFDKTKIA
LVPDHFVPNKDIKSAEQVNIMRKFAKKHGIVNFFEVGQMGIEHALLPEKGLVLPGDVVIG
ADSHTCTYGALTCFSTGVGSTDMAAAMATGKAWFKVPEAIKFVLKGNLQKWVSGKDIILY
IIGKIGVDGALYKSMEFTGNIKTLSMDDRFTIANMAIEAGAKNGIFDFDEITEAYVKGRA
KREYKVFERDEDAEYSEVYEINLDEIRPQVAFPHLPENTRSIDEVGKVKIDQVVIGSCTN
GRLSDMEIAYKILKGKKVHPDVRLLIFPATQEIYLECVKRGYIEEFIKAGAAISTPTCGP
CLGGHMGILARGERALATTNRNFVGRMGHPESEVYLSSPAVAAASAIAGYIVSPEEVE
NT seq
1257 nt
NT seq
+upstream
nt +downstream
nt
ttgggcttaacattgacacaaaagatattgtcagcaaaaattggtagagaggtcaaagca
ggagagttaatagaagtagatgtagatatggtgttgggcaatgacgtcactgctcctgtt
gctataagggaatttgagaaaataggaaaagaagaggtgtttgacaagactaaaattgcc
cttgttcccgaccattttgttcctaataaggacataaaatcggcagagcaagtgaatata
atgagaaaatttgcaaaaaaacatggaatagtgaatttctttgaagtagggcaaatgggg
atagagcacgctcttttacccgagaaaggacttgtacttcccggggatgtggtgataggt
gccgattctcatacatgcacttatggcgctcttacctgtttttctacaggtgtaggaagt
actgacatggcggcagcaatggctactggcaaggcgtggtttaaagtaccggaagctata
aaatttgtattaaaaggcaatttacaaaaatgggtaagtggaaaagatattatcttgtat
ataatcggaaaaataggagttgacggagctttatacaaatctatggaatttacagggaat
ataaaaactttgtcaatggatgatagattcacaattgccaatatggcaatagaagcaggg
gctaaaaacggtattttcgattttgacgaaattaccgaggcatatgttaaagggagagca
aaaagagaatataaagtgtttgaaagagatgaagatgccgagtacagtgaggtttatgag
ataaatttagatgagataagacctcaagtagcatttcctcatttgcctgaaaacactaga
agcattgatgaggttggaaaagtgaaaatagatcaggtagttattggctcttgtacgaat
ggacgtctctcagatatggagatagcgtataagatactaaaaggcaaaaaggttcatcct
gatgtaagacttttaattttccctgccacacaggaaatataccttgaatgtgtcaaaaga
ggttacattgaagagtttataaaagcaggcgccgcaatttctactcctacttgtggacct
tgccttggcgggcacatgggaattttggctagaggggaaagagcgttggcaactactaat
agaaattttgtaggaagaatgggacatcctgaaagcgaagtgtatctttcaagtccagct
gttgcggctgcttcggctattgcaggatatatcgtaagtccagaggaggtggaatga
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