Thermotoga maritima MSB8: THEMA_01905
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Entry
THEMA_01905 CDS
T02976
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
tmi
Thermotoga maritima MSB8
Pathway
tmi00290
Valine, leucine and isoleucine biosynthesis
tmi00660
C5-Branched dibasic acid metabolism
tmi01100
Metabolic pathways
tmi01110
Biosynthesis of secondary metabolites
tmi01210
2-Oxocarboxylic acid metabolism
tmi01230
Biosynthesis of amino acids
Module
tmi_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tmi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
THEMA_01905
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
THEMA_01905
Enzymes [BR:
tmi01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
THEMA_01905
4.2.1.35 (R)-2-methylmalate dehydratase
THEMA_01905
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Gene cluster
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AHD17690
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All DBs
Position
complement(361681..362934)
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AA seq
417 aa
AA seq
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MTLAEKILSQKAGRKVEPGEFLLLEPDIALANDITAPLAIKKFKEYGGKKVKYPDRVVLV
PDHFTPNKDIKSAMQVKMMREFAREQGIEKFFEIGRMGIEHVLLPEEGIVKSGDLVVGAD
SHTCTYGALGAFATGVGSTDIAGFYLIGKVWFRVPESIKVTLRGKFKDLVTAKDLVLKLI
SILGVDGANYKAIEFSGPGVKEISMDGRFTISNMAIEAGGKTGLFPVDEITIAYERERGI
EVEEMYPDEDAKYVREVEMDLSELEPQVAYPFLPSNAKDVSEAEKERIKIDQAVIGSCTN
GRIEDLRLAAQILKGRTVSPDVRCIIIPGSQKVYKQALKEGLIDIFIDAGCAVSTPTCGP
CLGGHMGVLAEGEVAISTTNRNFVGRMGHPNSKVFLASPAVAAASAIKGYIADPRKL
NT seq
1254 nt
NT seq
+upstream
nt +downstream
nt
atgacactcgcagaaaagatactctctcaaaaagcgggaagaaaggtggaaccgggagaa
tttctccttctggagccggacatcgctctcgcgaacgacataacggctccgcttgcgata
aagaagttcaaggagtacggtggaaagaaagtgaagtatccagacagagtggtgctcgtt
ccagaccatttcacccccaacaaggacataaagtccgccatgcaggtgaagatgatgaga
gaatttgccagagagcaggggatcgaaaagttcttcgaaataggcaggatgggtattgaa
cacgtgctgcttccagaagaaggaatcgtgaaatccggagatctcgtggtcggtgcggat
tcacacacctgtacctacggagcccttggagcgtttgcgaccggagtggggtccaccgac
atcgcgggcttctatctcataggaaaggtatggttccgtgtccccgagagtataaaggtg
actcttcgcgggaagttcaaggatctggtgactgccaaagacctcgtgttgaagctcatc
tcgatactcggtgtagatggagccaactacaaggcgatagaattctctggaccgggtgtg
aaagagatcagcatggacggccgttttaccatttcgaacatggcgatcgaggcgggagga
aagacgggactgtttccggtggacgagatcaccattgcctacgaaagagaaagaggcata
gaagtggaagagatgtacccggacgaagacgcaaaatacgtgagagaagtggaaatggac
ctttctgagctcgaacctcaggttgcatatcccttcctcccatccaacgcgaaggacgtt
tccgaagctgagaaagagagaataaagatagatcaggcggtgataggaagctgtaccaac
ggaaggatagaagatctcagacttgccgcgcagattctgaagggaaggacagtatcaccg
gacgttcgatgcatcataattccgggatcccagaaggtttacaaacaggctctcaaagaa
ggactcatcgacatattcatcgacgcgggctgcgccgtttccacgcccacatgtggaccc
tgtcttggcggacacatgggagtgctcgcagaaggagaggttgcgatctccacaacgaac
aggaacttcgttggaaggatgggacatccgaacagcaaggttttcctggcatctcctgca
gtggcggcggccagcgcaataaaaggatacatcgcagatccgagaaagctgtga
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