Trichechus manatus latirostris (Florida manatee): 101350137
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Entry
101350137 CDS
T05135
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu00310
Lysine degradation
tmu01100
Metabolic pathways
tmu05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
101350137
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
101350137
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
tmu03036
]
101350137
Enzymes [BR:
tmu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
101350137
Chromosome and associated proteins [BR:
tmu03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
101350137
HMT complexes
Dot1-containing complex
101350137
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
101350137
NCBI-ProteinID:
XP_004378555
UniProt:
A0A2Y9DPJ7
LinkDB
All DBs
Position
Unknown
AA seq
1741 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPCNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAGYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVQ
ESKAAVPADTPVDSGAEDEKAGATTVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSTA
NPERRPKKSQTALDLLHTQTVPQTAPSSPQDVYKSPHSPFYQLPPAVQRHASSPLLAAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNAQLLGAARQLFSHCQAQK
EEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLKEQTEQLEKDNRALRGQSLQLL
KARCEELKLDWPTLSLEKLLKEKQALKSQISEKQRRCLELQISIVELEKSQRQQELLQLK
SYVPADEALSVHLRGKGALSREQEPDPSRLHLELDCAKFSLPSFSSLSPELSMNGHTASY
ELYSTLSRSSSKQNTPQYLASPLDQEVVPCTPSHGGRPRLDKLAGLALPDYTRLSPAKIV
LRRHLSQDPAANGKAAAGELHPRVEHAKENGLAYQSPSISSSIKLSPQDPRPASPVALQM
AGDKGGEKGLKERPYGSGSETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARST
PSPVHQSRDPSSCLDKQIGANPHGGANSAAGSRGLALAPAGFSYSGSVAISGALAGSPAA
LAPGVEPATFDESSGSGSLLATLGSRSSTPQHPSLLVQARSSGPASPAHQLSGSPRLGGP
SQGALSDAAGRGDLPCDAGFSDPESEAKRRIVFTVAASTAGARPSPSSKHSPLASSTRGD
GGQGHGQDSRKRGRRKRSSAGTPGLSSGVSPKRRAPPSVAGLFTQSSGSPLNLNSMVNNI
NQPLEITAISSPENSLKSSPVPYQDHDQPPVLKKEKPLGQTNGAHYSPLTSDDEQGSEDE
PGSARIERKIATISLESKSPPKTLENGGGLANRKPVPASEPVNSSKWKSTFSPISDIGLA
KSADSPLQAGSTLSQNSLFAFRPALEEPGATDAKGATHPRKGFSGSLAGVDVPNPSTNPP
NGFALGGSLAADLSLHGFSDGASLTHKAPEVAGLSFPSQRGKEAGAPEANPFLSKRPLDG
LSGLKGDASKAREAGELGPTLGGASEKATLPPGGKAGRGRDRELDFPHGHNLFISAAAVP
SGGLLSGPGLAPAASSAGTHAPSTQTHRPFMGTFAPGAQFTLGPMSLQANLGSVAGSTVL
QSLFSAVPAAAGLVHVSSAATRLTNSHAMGTFSSGVAGGTVGGVFNHAVPSASSHPFGAS
FGSGAVCGSATLSLAPLQAVASTSAASFQAPSSVETRPPPLPPAQPLGRPPPAPPLPAQP
GLPPPLPNTALPPPPPLLAPNSEPVLLQSLASLPANHAFLPPASAASLSPANASLSIKLS
ALPHKASRPSFTVHRQPLPRLALAQAAPLLPQASPAAPSAVWVSLGMPPPYAAHLSGVKP
R
NT seq
5226 nt
NT seq
+upstream
nt +downstream
nt
atgggcgagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctgcccgtctacgacaaacatcacgatgctgctcacgaaatcatcgagacc
atccgatgggtctgcgaggaaatcccagatctcaagctcgccatggagaactacgtttta
attgactatgacaccaagagcttcgagagcatgcagaggctctgcgacaagtacaaccgg
gccatcgacagcatccaccagctgtggaaggggaccacgcagcccatgaagctgaacacg
cggccgtgcaacgggctgctgcggcacatcctgcagcaggtctacaaccactcggtcacc
gaccctgagaagctcaacaactacgagcccttctcgcctgaggtgtatggcgagacctcc
ttcgacctggtggcacagatgatcgacgagatcaagatgaccgaggacgacctgttcgtg
gacctgggcagcggagtgggccaggttgtgctccaggtggctgcagccaccaactgcaaa
catcactacggcgtggagaaagctgacatcccagccaagtacgcggagacgatggacaga
gaattcaggaagtggatgaaatggtatggaaaaaagcatgccggatacacactggaaaga
ggcgatttcctctcagaagagtggcgtgagcggattgcgaacacgagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggaacgatttgcaaacatg
aaggaaggcggcagaatcgtgtcctcgaaaccttttgcacctctgaacttcagaataaac
agtagaaacttgagcgatatcggcaccatcatgcgtgtcgtggagctgtcgcccctgaag
ggctcagtctcgtggacggggaagccggtctcctactacctgcacactatcgaccgaacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggaacaagaggca
gctaggcgccggcagcaacgggagaacaagagcaacacaaccactccaaccaaggtccag
gagagcaaggcggcagtccccgcggacacccccgtggactctggtgctgaggatgagaaa
gccggggccaccactgtcaaaaagccatccccctccaaagcccgcaagaagaagctgaac
aagaagggacggaagatggctggccggaagcgtgggcgccccaagaaaatgagcactgca
aaccccgagcgcagacccaagaagagccaaaccgcactggacctcctgcacacgcagacc
gtgccccagactgccccgtcctcgcctcaggatgtgtacaagtcacctcacagcccgttc
taccagctacctccggccgtgcagcggcacgcgtccagcccgctgctggcggcgcccacc
cctcccgcgctacagaagctgctagagtctttcaagatccagtacctgcagttcttggcg
tacacaaagaccccgcagtacaaggccaacctgcagcagctgctggaccaagagaaggag
aagaacgcccagctgctgggcgctgctcggcagctcttcagccactgccaggcgcagaag
gaggagatcaggcggctcttccaacagaagctggacgagctgggtgtgaaggccctgacc
tacaatgacctgatccaagcacagaaggagatctctgcgcacaaccagcagttgaaggag
cagacggagcagctagagaaggacaaccgcgcgttgcggggccagagcctgcagctgctc
aaggctcggtgtgaggagctgaagctggactggcccaccctgtccctggagaagctgctg
aaggagaagcaggccctcaagagccagatctccgagaaacagaggcgctgcctggagctg
cagatcagcatcgtggagctggagaagagccagcgacagcaggagctgctgcagctcaag
tcctacgtgccagcggatgaggccctgtccgtgcacctgcgtgggaagggcgcgctgagc
cgggagcaagagcccgaccccagccgcctccacctggagctcgactgcgccaagttctcg
ctgccctccttcagcagcctgagcccggagctctccatgaacggccacacggccagctat
gagctatacagcacactcagccggtcctcgtccaagcagaacacccctcagtacctggcc
tcgcccctggaccaggaggtggtgccctgcacgcccagccatggtggccggccacggctg
gacaagctggctggcctggccctgcccgactacacacggctctccccggccaagattgtg
ctgcggcgccacctgagccaggaccccgctgccaacgggaaggcagccgccggcgagctg
cacccgcgcgtggagcacgccaaggagaatggcctcgcctatcagagccccagcatctcc
agcagcatcaagctgagcccacaagaccctcggcccgcgtcccccgtggccttacagatg
gcaggggacaagggtggcgagaagggcttgaaggagcgcccctacggcagcggcagtgag
accatcaccagcctgcccgtcagcatcccgcttagcaccgtgcagcccaacaagctccca
gtcagcatccccctggccagtgtggtattgcccagccgtgctgagcgagcgaggagcacc
ccgagccctgtgcatcagagccgtgacccctcctcctgcctcgacaagcagatcggtgct
aacccccatggcggtgcaaacagtgctgctggaagcagaggcctggccctggcgcctgca
ggcttctcctactctggctcggtggccatcagtggggccctggccggcagcccggcagcc
ctcgcccctggggtcgagccagccaccttcgacgagtcttcgggctcaggcagcctcctc
gccaccctgggctcacgcagctccaccccacagcacccctccctgctggtccaggcccgc
agctccggcccggcctcccccgcccaccagctctcggggagcccccggctcgggggtcct
tcccagggtgcgctctccgacgccgccggcaggggcgacctgccatgcgacgcaggcttc
tctgaccccgagagcgaggccaagcgcaggattgttttcaccgtggcagccagcacagcg
ggtgcccggccgtccccctccagcaagcacagccccctggccagcagcacccgtggggat
ggcggacagggccacgggcaggacagccggaagcgaggccgcaggaagcgctcatcagca
ggcacccccggcctgagctcgggcgtgtcccccaagcgccgggccccaccgtctgtcgcc
gggctctttacgcagtcctcggggtcccccctgaacctcaactccatggtcaacaacatt
aaccagcccctggagatcacggccatctcgtcccccgagaactccctgaagagctcgccc
gtcccctaccaggaccatgaccagccgcctgtactcaagaaggagaagccgctgggccag
accaacggggcccactactcgcccctgacgtcggacgacgagcagggctccgaggatgag
cccggcagtgccagaattgagaggaaaatcgcaacaatctccttagaaagcaaatctccc
ccgaaaaccttggaaaacggtggtggcctggccaacaggaagccggtgccggccagtgag
ccggtcaacagcagcaagtggaagtccaccttctcgcccatctcggacatcggcctggcc
aagtcggccgacagcccactgcaggccggctccaccctgagccagaactccttgtttgca
tttcggcctgccctggaggagcccggtgccactgatgccaagggggccacacaccccagg
aagggcttctcgggctccttggcgggggtggacgtgcccaacccgagcaccaaccccccc
aacgggttcgccctcggcgggtccctggccgccgacctcagtttacacggcttcagcgat
ggtgcttctctcacccacaaggcccccgaggtggccgggctgagtttcccctcccagcgg
ggcaaggaggctggtgcccctgaggccaaccccttcctgagcaagcggccgctggatgga
ctgagtggcctgaagggcgatgccagcaaggcccgtgaggccggcgagctgggcccgacc
ttgggcggtgcctctgagaaggccacgctgccgcccggcgggaaggcaggccgaggccgg
gaccgcgagctggacttcccccacggccataacctcttcatctcggccgctgctgtgccc
tccgggggcctcctcagcggcccgggcctggccccagcagcgtcctctgcgggcacccac
gccccctccacccagacgcaccgccccttcatgggcacctttgcccctggcgcccagttc
accctgggccccatgtccctgcaggccaacctgggctcggtggcgggctcaaccgtgctg
cagtccctgttcagtgccgtgccggccgctgcgggtctggtgcacgtgtcatcagcagcc
accaggctcaccaactcgcacgccatgggcaccttctcttccggagtcgcgggcggaact
gtcggaggtgtctttaaccacgcggtgccttctgcctcttctcatccgttcggagccagt
ttcggcagcggggctgtctgtggcagcgccacgctgagcttagccccgctgcaggcggtg
gccagcacctccgccgcttcctttcaggccccgtcctctgtcgagacccggccgcccccg
ctgcctcctgctcagcccctgggccggcctccccctgctcctcctcttcctgcgcagcct
ggcctcccaccccctctgcctaacaccgccttgcctcctcccccgccgctgctggcacct
aactctgagcccgtgcttctgcagagcctggcgtccctccctgctaaccacgctttcttg
ccccccgcctctgccgcctccctgtcgcctgctaacgcctctttgtctatcaagctctct
gctctgcctcacaaggcctcccgcccctccttcacggtccaccgccagcctctgccccgg
ctggccctggcgcaggctgcacccctcctcccacaggccagccctgccgcgccctctgcg
gtctgggtttcccttggcatgccgcctccttatgccgcgcacctttcgggggttaagccg
cgctaa
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integrated database retrieval system
