Trichechus manatus latirostris (Florida manatee): 101351614
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Entry
101351614 CDS
T05135
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu00010
Glycolysis / Gluconeogenesis
tmu00020
Citrate cycle (TCA cycle)
tmu00620
Pyruvate metabolism
tmu00785
Lipoic acid metabolism
tmu01100
Metabolic pathways
tmu01200
Carbon metabolism
tmu01210
2-Oxocarboxylic acid metabolism
tmu04066
HIF-1 signaling pathway
tmu04922
Glucagon signaling pathway
tmu05230
Central carbon metabolism in cancer
tmu05415
Diabetic cardiomyopathy
Module
tmu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
101351614
00020 Citrate cycle (TCA cycle)
101351614
00620 Pyruvate metabolism
101351614
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
101351614
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
101351614
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
101351614
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101351614
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101351614
Enzymes [BR:
tmu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
101351614
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
101351614
NCBI-ProteinID:
XP_023593029
UniProt:
A0A2Y9RM64
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILTELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDVLCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGHHIYCSEPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgctgccgtctcccgcgtgttgtcgggcgccgcccagaagccggct
agcagagtgctggtggcatcccgtaactttgcaaatgatgctacatttgaaattaagaaa
tgtgatctccatcggttggaagagggtccccctgtcacaactgtgctcaccagggaggat
gggctcaaatactacaggatgatgcagactgtccgccggatggaattaaaagcagatcag
ctgtataaacagaaaatcatccggggcttctgccacttgtgtgatggtcaggaagcttgc
tgtgtggggctggaggctggtataaatcccaccgaccatctcattacagcctatcgggcc
catggctttacctttactcgtggtctttctgtccgagaaatcctcacagaactaacagga
cgaagaggaggttgtgctaaaggaaaaggaggctcaatgcatatgtatgccaagaacttc
tacgggggcaatggcattgtcggggctcaggtgcccctgggagctggcattgctctggcc
tgcaagtacaatggaaaagatgaagtctgcttgactctatatggggatggtgctgctaat
cagggtcagatatttgaagcttacaatatggcagctttgtggaaattaccttgtattttc
atctgtgagaacaaccgctatggaatgggaacatctgtcgagagagcagcagccagcact
gactactacaagagaggcgattttattcctgggctgagggtagatggaatggatgtcctg
tgtgtccgggaggctacaaggtttgcagctgcctattgcagatctggaaaggggcccata
ctgatggaactgcagacataccggtaccacggacacagtatgagtgatcctggagtcagt
taccgtacaagagaagaaattcaggaagtaaggagtaagagtgatcctattatgcttctc
aaggatagaatggtgaacagcaaccttgccagtgttgaagaattaaaggaaattgacgtt
gaagtgaggaaagaaattgaggatgcagcccagtttgctacagctgatccggaaccgcct
ttggaagaactaggccatcacatctactgcagtgaaccaccttttgaagttcgtggtgca
aatcagtggatcaagtttaagtcagtcagttaa
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