Trichechus manatus latirostris (Florida manatee): 101360843
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Entry
101360843 CDS
T05135
Name
(RefSeq) bifunctional purine biosynthesis protein PURH isoform X1
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu00230
Purine metabolism
tmu00670
One carbon pool by folate
tmu01100
Metabolic pathways
tmu01523
Antifolate resistance
Module
tmu_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101360843
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101360843
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101360843
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
tmu04147
]
101360843
Enzymes [BR:
tmu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
101360843
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
101360843
Exosome [BR:
tmu04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
101360843
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
101360843
NCBI-ProteinID:
XP_004376345
UniProt:
A0A2Y9DKH0
LinkDB
All DBs
Position
Unknown
AA seq
592 aa
AA seq
DB search
MAPGQLALFSVSDKTGLVEFARNLTSVGLNLVASGGTAKALRDAGLTVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVVCNLYPFVKTVSSPDITVEAA
VEQIDIGGVTLLRAAAKNHARVTVVCDPEDYAAVSMEMQSSDSKDTSLEARRQLALKAFT
HTAQYDEAISDYFRRQYSKGISQMPLRYGMNPHQTPAQLYTLEPKLPITVLNGAPGFINL
CDALNAWQLVKELREALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPIS
TAYARARGADRMSSFGDFIALSDVCDVPTAKIISREVSDGIIAPGYEEEALKILSKKKSG
NYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVIDRSLFSNVVTKNKDLPESAVRDLII
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANCWWLRHHPRVLSMKFKT
GVKRAEISNAIDQYVTGTIGEDEDLVKWKELFEEVPELLTEAEKKEWIGKLSEVSVSSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADQVVIEACDELGIILAHTSLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcgcccggccagcttgccttgtttagtgtctcagacaaaaccggccttgtggaattt
gccagaaacctaacttctgttggtttgaatctggttgcttctggagggacagcaaaagct
ctgagggatgctggtctgacagtcagagatgtctctgagctgacagggtttcctgaaatg
ttagggggacgcgtgaaaaccttacatcccgcggtccatgcaggaatcttggctcgtaat
atcccagaagataatgctgacatggccagacttgatttcaatcttataagagttgttgtt
tgtaatctgtatccatttgtgaagaccgtgtcttctccagacataactgttgaggcagct
gttgagcaaattgatattggtggagtaactttactgagagcagcagccaaaaaccatgcc
cgtgtgacagtagtgtgtgatccagaggactacgcagcagtgtccatggagatgcagagt
tccgatagtaaagacacctctttggaggctagacgccagttagccttgaaggcattcact
catacggcacaatatgatgaagcaatttcagattacttcaggaggcagtatagtaaaggg
atatctcagatgcctttgaggtatggaatgaaccctcatcaaacgcctgcccagttgtac
acactggagcccaagcttcccatcacagttctaaatggagctcctggatttataaacttg
tgtgatgctttgaatgcctggcagctggtaaaggaactcagagaagctttaggcattcca
gctgctgcctctttcaaacatgtcagtccagcgggcgctgctgttggaattccactcagt
gaagatgaggccaaagtctgcatggtctatgatctctacaagacccttacacccatatca
actgcatatgctagagcaagaggggccgataggatgtcttcatttggtgattttattgcg
ttatctgatgtttgtgatgtccctactgcaaaaattatctccagagaggtatctgatggt
attattgctccaggatatgaagaagaagccttgaaaatcctttctaaaaagaaaagtgga
aactactgtgttcttcagatggaccagtcttacaaaccagatgaaaatgaagttcgaact
ctctttggtcttcatttaagccagaagaggaataatggtgtcattgacaggtctttattt
agcaatgttgttaccaagaataaagatttgccagagtctgctgtcagagacctcatcatc
gccaccattgctgtcaagtacactcagtctaattctgtgtgctatgccaagaacggtcag
gttattggcatcggagcaggacagcagtctcggatacactgtacacgccttgcaggggat
aaagcaaactgttggtggcttagacatcacccacgcgtactttcaatgaagtttaaaaca
ggagtgaagagagcagaaatctcgaatgccatcgatcaatacgttactggaaccattggc
gaggatgaagatttggtaaaatggaaggaactgtttgaggaagtccctgaactgttaacc
gaggcagagaagaaagaatggataggcaaacttagtgaggtttctgtcagttctgatgcc
ttctttcctttcagggataatgtggacagagctaaaaggagtggtgtggcgtatattgct
gctccttccggttctgctgctgaccaagttgtgattgaggcgtgtgatgaactggggata
atcctcgctcataccagtcttcggctctttcatcactga
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