Tsukamurella pulmonis: TPB0596_16310
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Entry
TPB0596_16310 CDS
T08311
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
tpul
Tsukamurella pulmonis
Pathway
tpul00290
Valine, leucine and isoleucine biosynthesis
tpul00660
C5-Branched dibasic acid metabolism
tpul01100
Metabolic pathways
tpul01110
Biosynthesis of secondary metabolites
tpul01210
2-Oxocarboxylic acid metabolism
tpul01230
Biosynthesis of amino acids
Module
tpul_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tpul00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
TPB0596_16310 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
TPB0596_16310 (leuC)
Enzymes [BR:
tpul01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
TPB0596_16310 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
TPB0596_16310 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
BDD81868
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Position
1605490..1606989
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AA seq
499 aa
AA seq
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MVGFNAQPAPAGEAKMMKQVGSMQPRTMAEKVWDQHVVVRGEGEGASREPDLIYIDLHLV
HEVTSPQAFDGLRLAGRPVRRPDLTIATEDHNVPTDTLVQPIADEVSRLQVETLRRNCAE
FGVRLHSMGDGEQGIVHVMGPQLGLTQPGMTVVCGDSHTSTHGAFGAIAMGIGTSEVEHV
LATQTLALKPFKTMAINVSGELQPGVTSKDLILAIIAKIGTGGGQGYVLEYRGSAIEKLS
MEARMTICNMSIEAGARAGLIAPDRITYDYIEGREHAPKGADWDAAIEAWDALRTDEGAV
FDAEVDIDGSALTPFVTWGTNPGQGAPLSASVPDPESFGSDGEKETAAKALQYMGLEAGT
PLRDIAVDAVFVGSCTNGRIEDLRAVAEILRGRKVADGVRMLVVPGSMRVRAQAEEEGLG
QVFLDAGAEWRQAGCSMCLGMNPDQLAAGERSASTSNRNFEGRQGKGSRTHLVSPAVAAA
TAVRGTLSAPADLAPVAGA
NT seq
1500 nt
NT seq
+upstream
nt +downstream
nt
atggtgggattcaacgcgcagcccgcgcccgccggcgaagcgaagatgatgaagcaggtg
ggaagcatgcagccgcgcacaatggccgagaaggtctgggaccagcacgtcgtcgtccgg
ggggagggcgagggtgcctcgcgcgagcccgacctcatctacatcgacctgcacctcgtg
cacgaggtcaccagcccgcaggccttcgacgggctgcgtctggcgggccggccggtgcgc
cgccccgacctgaccatcgccaccgaggaccacaacgtgcccacggacacgctggtccag
cccatcgccgacgaggtctcccggctccaggtggagacgctgcgccgcaactgcgccgag
ttcggggtgcgcctgcactcgatgggcgacggcgagcagggcatcgtccacgtgatggga
ccgcagctcgggctcacccagcccggcatgacggtcgtgtgcggcgacagtcacacctcg
acgcacggcgccttcggcgcgatcgccatggggatcggcacctccgaggtcgagcacgtg
ctggcgacgcagacgctggcgctcaagcccttcaagaccatggccatcaacgtctccggc
gagttgcagcccggcgtcacctccaaggacctgatcctggcgatcatcgccaagatcggc
accggcggcggccagggctacgtcctcgagtaccgcggcagcgccatcgagaagctctcg
atggaggcgcggatgaccatctgcaacatgtcgatcgaggccggcgcccgcgccgggctg
atcgcgcccgaccggatcacctacgactacatcgagggtcgcgagcacgcgcccaagggt
gccgactgggatgccgcgatcgaggcgtgggacgccctgcgcaccgacgagggggccgtt
ttcgacgccgaggtcgacatcgacggcagcgcgctgaccccgttcgtcacctgggggacg
aatccgggccagggtgcgccgctgagcgcgtcggtgcccgatcccgagtcgttcggctcc
gacggcgagaaggagaccgccgcgaaggccctgcagtacatgggcctcgaggcgggcacc
ccgctgcgcgacatcgccgtcgacgccgtgttcgtcggctcgtgcaccaacggccggatc
gaggacctgcgcgccgtcgccgagatcctccggggccgcaaggtggccgacggggtgcgc
atgctcgtcgttcccggatcgatgcgggtgcgcgcgcaggccgaggaggagggcctcggg
caggtcttcctcgacgcgggcgccgagtggcgccaggccggatgctcgatgtgcctgggc
atgaaccccgatcagctcgccgccggagagcgttccgcgtccacgtcgaaccgcaacttc
gaggggcggcagggcaagggcagtcgcacgcacctggtctccccggcggtggccgccgcc
acggccgtgcgcggcacgctctccgcccccgccgatctggcccccgtcgccggcgcgtag
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