Pseudothermotoga thermarum: Theth_0499
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Entry
Theth_0499 CDS
T01554
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
tta
Pseudothermotoga thermarum
Pathway
tta00290
Valine, leucine and isoleucine biosynthesis
tta00660
C5-Branched dibasic acid metabolism
tta01100
Metabolic pathways
tta01110
Biosynthesis of secondary metabolites
tta01210
2-Oxocarboxylic acid metabolism
tta01230
Biosynthesis of amino acids
Module
tta_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tta00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Theth_0499
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Theth_0499
Enzymes [BR:
tta01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
Theth_0499
4.2.1.35 (R)-2-methylmalate dehydratase
Theth_0499
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Gene cluster
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AEH50590
UniProt:
F7YWZ8
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Position
complement(497485..498762)
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AA seq
425 aa
AA seq
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MGYTITEKILLKHSDKKEIFPGDLIFVKVDLVLANDITAPLAIKEFKKIGVEKVFDPEKI
ALVPDHSTPNKDIKSAEQAKITRLFAKEQNIRYYYEVGRAGIAHVLLPDEGLIAPGDCVV
GADSHTCTYGALGAFSTGIGSTDAAYAMAFGEVWLKVPETVKFIYYGKLPKWVGGKDLIL
YTIGKIGVDGARYMAMEFAGEAIKNLGMADRFTMCNMAVEAGAKNGIIEPDEITLEYLKK
RVKRKYELIFSDKDANYKEVYEWDVSKLEPMVAFPHLPSNVYPVSEAASKNITLDQVYIG
SCTNGRLEDLRIAAKILKGHKVNPNLRLIITPATPEIYLQALKEGLIEIFLEAGATITPP
SCGPCLGGHLGVLAEGEKALSTTNRNFVGRMGHPKSEVYLANPAVAAASAILGRIAAPWE
VEVKE
NT seq
1278 nt
NT seq
+upstream
nt +downstream
nt
atgggttacacaataaccgaaaagattttgctaaagcattctgacaaaaaagaaatattc
ccaggcgatttgatcttcgtaaaagttgaccttgttcttgcaaacgatataactgctccg
cttgccataaaagagttcaaaaaaattggtgttgaaaaagtttttgatccagagaaaata
gctttggttccagatcactcgacgccaaacaaagatatcaaatcggcagaacaggcaaag
attacaagactttttgcaaaagagcaaaacataaggtattactacgaggttggcagagct
gggatagcgcatgttcttttgccagacgaaggtttgatagctcctggtgattgtgttgtt
ggggcagattcgcacacctgcacttatggtgccttaggagccttttcaactgggattgga
agcacggatgccgcgtatgccatggcttttggtgaagtgtggttgaaagtaccagaaact
gtaaagttcatctactatggaaagttaccaaagtgggtagggggaaaagatttaatcctt
tacacaataggaaaaatcggtgtagatggtgcacgatacatggcaatggaatttgctggt
gaagccatcaaaaaccttggtatggcagatagattcacaatgtgcaacatggctgtggaa
gctggtgcaaaaaacgggataatcgaacctgatgaaataacactggagtacctcaagaaa
agggttaaaaggaaatacgaactgatttttagcgacaaagatgcaaattacaaagaagtt
tacgagtgggacgtctcgaaactcgaaccgatggttgcatttccacatttacccagcaac
gtttatccagtttcggaagctgcaagcaaaaacataacgctagatcaagtttacataggc
tcttgcaccaacggaagacttgaggatttgagaatcgcggcaaaaattttaaagggtcac
aaggtcaatcccaacttgaggctcataataaccccagccacacccgagatctaccttcaa
gctttgaaagagggtttgatagaaatctttctggaagccggtgccacaatcacaccaccc
agctgtggaccatgtcttggaggacaccttggagtgcttgccgaaggagaaaaagcttta
agcacaaccaacagaaacttcgtcggaagaatggggcatcccaaaagcgaagtatacctt
gcaaaccctgctgttgcagcagcctcagcaatccttggaagaatcgctgcgccgtgggaa
gtggaggtgaaagaatga
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