Thermus thermophilus HB8: TTHA1228
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Entry
TTHA1228 CDS
T00220
Symbol
TTHA1228
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
ttj
Thermus thermophilus HB8
Pathway
ttj00290
Valine, leucine and isoleucine biosynthesis
ttj00660
C5-Branched dibasic acid metabolism
ttj01100
Metabolic pathways
ttj01110
Biosynthesis of secondary metabolites
ttj01210
2-Oxocarboxylic acid metabolism
ttj01230
Biosynthesis of amino acids
Module
ttj_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ttj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
TTHA1228 (TTHA1228)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
TTHA1228 (TTHA1228)
Enzymes [BR:
ttj01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
TTHA1228 (TTHA1228)
4.2.1.35 (R)-2-methylmalate dehydratase
TTHA1228 (TTHA1228)
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GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
BAD71051
UniProt:
Q9ZND5
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All DBs
Position
1:1166248..1167666
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AA seq
472 aa
AA seq
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MGKTLYEKVWEAHEVRKLKNGQSQLFIDLHLLHEVTSPQAFGMLKDLGLRVRYPHRTFAT
VDHIVPTHDRTEPFQDPLAQSMLEALRANTREHGITFFDLGSGNQGIVHVIGPQLGLTQP
GMTIACGDSHTSTHGAFGAVAFGIGTSQVRDVLATQTLAAQKLKVRRINVEGRLAPGVYA
KDVILHIIRHLGVKGGLGYAYEYGGSAVEAMDMESRMTLCNMSIEGGARIGYVNPDETTF
QYLEGRPYVPKGSEWEEAKRRWLAWRSDPDASYDDVVTFRAEEIAPTVTWGITPGQAIPI
DGRIPLLEELPEEERPVAEEALAYMGFRPGQPIKGVPIQVAFIGSCTNARLSDLREVARY
LKGHKVKKGVRALVVPGSEWVARKAEEEGIAEVFREAGFEWRMPGCSMCLAMNPDRLEGD
ELCASSSNRNYKGRMGSPRGRTVLMSPLMVAAAAVAGEIADAREVFGLAGVR
NT seq
1419 nt
NT seq
+upstream
nt +downstream
nt
atgggaaagacgctctacgagaaggtttgggaagcccacgaggtgaggaagctcaaaaac
ggccaaagccagctcttcatagacctccacctcctccacgaggtcacgagcccccaggcc
ttcgggatgctcaaggaccttggccttcgggtacgctacccccaccgcaccttcgccacc
gtggaccacatcgtccccacccacgaccgcaccgagcccttccaggaccctctggcccag
agcatgctggaggccctcagggcgaacacaagggagcacggcatcaccttctttgacctg
ggaagcggcaaccaaggcatcgtccacgtcatcgggccccagctcggcctcacccagccc
gggatgaccatcgcctgcggggactcccacacctccacccacggggccttcggggccgtg
gccttcggcatcggcacgagccaggtccgggacgtcctcgccacccagaccctcgccgcc
caaaagctcaaggtgcggcggatcaacgtggaggggaggctcgcccccggggtctacgcc
aaggacgtgatcctccacatcatccgccacctgggggtgaaggggggcttgggctacgcc
tatgaatacgggggaagcgccgtggaggccatggacatggaaagccgcatgaccctctgc
aacatgtccattgagggcggagcccgcatcggctacgtgaaccccgacgagaccaccttc
cagtacctcgagggccgcccctacgtccccaaggggtccgagtgggaggaggccaagagg
aggtggctcgcttggcgctccgaccccgacgcctcctacgacgacgtggtcaccttccgc
gccgaggagatcgcccccaccgtcacctggggcatcaccccgggccaggccatccccatt
gacggcaggatccccctcctggaggagctccccgaggaggagcgccccgtggccgaggag
gctttggcctacatgggcttcaggccgggccagcccatcaagggggtgcccatccaggtg
gccttcatcggaagctgcaccaacgccaggctttccgacctccgggaggtggcccgctac
ctcaaggggcacaaggtgaagaagggggtgcgggccctggtggtgccgggctcggagtgg
gtggcgaggaaggccgaggaggaggggatcgccgaggtcttccgcgaggcggggtttgaa
tggcggatgcccggctgctccatgtgcctcgccatgaacccggaccggctggaaggggac
gagctttgcgccagcagctccaaccggaactacaagggacgcatgggaagccccaggggc
cgcaccgtcctcatgagccccctcatggtggcggcggcggccgtggccggggagatcgcc
gacgcccgggaggtcttcggcctggcgggcgtccgctga
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