Thermus thermophilus JL-18: TtJL18_0819
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Entry
TtJL18_0819 CDS
T02009
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
ttl
Thermus thermophilus JL-18
Pathway
ttl00290
Valine, leucine and isoleucine biosynthesis
ttl00660
C5-Branched dibasic acid metabolism
ttl01100
Metabolic pathways
ttl01110
Biosynthesis of secondary metabolites
ttl01210
2-Oxocarboxylic acid metabolism
ttl01230
Biosynthesis of amino acids
Module
ttl_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ttl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
TtJL18_0819
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
TtJL18_0819
Enzymes [BR:
ttl01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
TtJL18_0819
4.2.1.35 (R)-2-methylmalate dehydratase
TtJL18_0819
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AFH38722
UniProt:
H9ZQW2
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Position
complement(741692..743110)
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AA seq
472 aa
AA seq
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MGKTLYEKVWEAHEVRKLRNGQSQLFIDLHLLHEVTSPQAFGMLKDLGLRVRYPHRTFAT
VDHIVPTHDRTEPFQDPLAQSMLEALRANTREHGITFFDLGSGNQGIVHVIGPQLGLTQP
GMTIACGDSHTSTHGAFGAVAFGIGTSQVRDVLATQTLAAQKLKVRRINVEGRLAPGVYA
KDVILHIIRHLGVKGGLGYAYEYGGSAVEAMDMESRMTLCNMSIEGGARIGYVNPDETTF
QYLEGRPYVPKGSEWEEAKKRWLAWRSDPDASYDDVVTFRAEEIAPTVTWGITPGQAIPI
DGRIPLLEELPPEERPVAEEALAYMGFRPGQPIKGVPIQVAFIGSCTNARLSDLREVARY
LRGHRVKRGVRALVVPGSEWVARKAEEEGIAEVFREAGFEWRMPGCSMCLAMNPDRLEGD
ELCASSSNRNYKGRMGSPRGRTVLMSPLMVAAAAVAGEIADAREVFGLVGAR
NT seq
1419 nt
NT seq
+upstream
nt +downstream
nt
atgggaaagacgctctacgagaaggtttgggaagcccacgaggtgaggaagctcagaaac
ggccaaagccagctcttcatagacctccacctcctccacgaggtcacgagcccccaggcc
ttcgggatgctcaaggaccttggccttcgggtacgctacccccaccgcaccttcgccacc
gtggaccacatcgtccccacccacgaccgcaccgagcccttccaggaccctctggcccag
agcatgctggaggccctcagggcgaacacaagggagcacggcatcaccttctttgacctg
gggagcggcaaccaaggcatcgtccacgtcatcgggccccagctcggcctcacccagccc
gggatgaccatcgcctgcggggactcccacacctccacccacggggccttcggagccgtg
gccttcggcatcggcacgagccaggtccgggacgtcctcgccacccagaccctcgccgcc
caaaagctcaaggtgcggcggatcaacgtggaggggaggctcgcccccggggtctacgcc
aaggacgtgatcctccacatcatccgccacctgggggtgaaggggggcttgggctacgcc
tatgaatacgggggaagcgccgtggaggccatggacatggaaagccgcatgaccctctgc
aacatgtccattgagggcggagcccgcatcggctacgtgaaccccgacgagaccaccttc
cagtacctcgagggccgcccctacgtccccaaggggtccgagtgggaggaggccaagaaa
aggtggctcgcttggcgctccgaccccgacgcctcctacgacgacgtggtcaccttccgc
gccgaggagatcgcccccacggtcacctggggcatcaccccggggcaggccatccccata
gacggccgtattccccttctggaggagcttccccccgaggagcgccccgtggccgaggag
gctttggcctacatgggcttcaggccggggcagcccatcaagggggtgcccatccaggtg
gccttcatcggaagctgcaccaacgccaggctttccgacctgcgggaggtggcccgctac
ctccggggccaccgggtgaagcggggggtgagggccctggtggtgccgggctcggagtgg
gtggcgaggaaggccgaggaggaggggatcgccgaggtcttccgggaggcggggtttgag
tggcggatgcccggctgctccatgtgcctcgccatgaacccggaccggctggaaggggac
gaactttgcgccagcagctccaaccggaactacaagggacgcatgggaagccccaggggg
cgcaccgtcctcatgagccccctcatggtggcggcagcggcggtggccggggaaatcgcc
gacgcccgggaggtcttcggcctggtgggtgcgcgctaa
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