Tupaia chinensis (Chinese tree shrew): 102469167 Help Entry 102469167         CDS       T02978                                  Symbol INSR Name (RefSeq) insulin receptor   KO K04527   insulin receptor [EC:2.7.10.1] Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup04010   MAPK signaling pathway tup04014   Ras signaling pathway tup04015   Rap1 signaling pathway tup04022   cGMP-PKG signaling pathway tup04066   HIF-1 signaling pathway tup04068   FoxO signaling pathway tup04072   Phospholipase D signaling pathway tup04150   mTOR signaling pathway tup04151   PI3K-Akt signaling pathway tup04152   AMPK signaling pathway tup04211   Longevity regulating pathway tup04213   Longevity regulating pathway - multiple species tup04520   Adherens junction tup04910   Insulin signaling pathway tup04913   Ovarian steroidogenesis tup04923   Regulation of lipolysis in adipocytes tup04930   Type II diabetes mellitus tup04931   Insulin resistance tup04932   Non-alcoholic fatty liver disease tup04960   Aldosterone-regulated sodium reabsorption tup05010   Alzheimer disease tup05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:tup00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102469167 (INSR)    04014 Ras signaling pathway     102469167 (INSR)    04015 Rap1 signaling pathway     102469167 (INSR)    04066 HIF-1 signaling pathway     102469167 (INSR)    04068 FoxO signaling pathway     102469167 (INSR)    04072 Phospholipase D signaling pathway     102469167 (INSR)    04022 cGMP-PKG signaling pathway     102469167 (INSR)    04151 PI3K-Akt signaling pathway     102469167 (INSR)    04152 AMPK signaling pathway     102469167 (INSR)    04150 mTOR signaling pathway     102469167 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     102469167 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102469167 (INSR)    04923 Regulation of lipolysis in adipocytes     102469167 (INSR)    04913 Ovarian steroidogenesis     102469167 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     102469167 (INSR)   09149 Aging    04211 Longevity regulating pathway     102469167 (INSR)    04213 Longevity regulating pathway - multiple species     102469167 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     102469167 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     102469167 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102469167 (INSR)    04932 Non-alcoholic fatty liver disease     102469167 (INSR)    04931 Insulin resistance     102469167 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:tup01001]     102469167 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:tup04090]     102469167 (INSR) Enzymes [BR:tup01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      102469167 (INSR) Protein kinases [BR:tup01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    102469167 (INSR) CD molecules [BR:tup04090]  Proteins   102469167 (INSR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  102469167 NCBI-ProteinID:  XP_014440403 LinkDB All DBs Position Un AA seq 1382 aa AA seqDB search MGAGDRRGAAAAPLLVAVAALLVGAAGHLYPGEVCPGMDIRNNLTRLRELENCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYNLMSITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTSCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL GNCSEPNDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRKQG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC TVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRVIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIAPKTNGDQASCENELLKFSHIRTSSDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQNQPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQAEDSELYELDYCLKGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFVPRKTSPGTGAEDTRPSRKRRSLGDVGNVTVAIPTVPGF PNTSSTSVPTSPEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDVPEERCSVAVYI SARTMPEAKADDIVGPVTHEIFENNVVHLMWQGPKEPNGLIVLYEVSYRRYGDEELHLCV SRKHYALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG PLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR EKITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKG FTCHHVVRLLGVVSRGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN CPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSDENKAPESEELEME FEDMESVPLDQSSHCQREEVGGRDGGSSLGLKRNYEEHIPYTHMNGGKKNGRILTLPRSN PS NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt atgggcgccggggaccggcggggggcggcggccgcgccgctgctggtggcggtggccgcg ctgttggtgggcgccgcgggacacctgtaccccggagaggtgtgtcccggcatggatatt cggaacaacctcaccaggctgcgtgaactggagaactgctccgtcatcgaaggacacttg cagatcctcctgatgttcaagaccaggcccgaagacttccgggacctcagtttccccaaa ctcatcatgatcaccgactacttgctgctcttccgggtctacgggctcgagagcctgaag gacctgttccccaacctcaccgtcatccggggctcccgcctcttcttcaactacgcgctg gtcatcttcgagatggtccacctcaaggagctgggcctgtacaacctcatgagtatcacg cggggctccgtccgcatcgagaagaacaacgagctctgctacctggccaccatcgactgg tcccggatcctggattccgtggaggataattacatcgtgttgaacaaggacgacaatgag gagtgtggggacatctgtccaggcaccgcgaagggcaagaccagctgccccgccacggtc atcaacgggcagtttgtcgagcgatgttggacacacagccattgccagaaagtctgtccc accatctgcaagtcgcatgggtgcaccgccgaaggcctctgctgccacagcgaatgcttg ggcaactgttcggagcccaacgaccccaccaagtgcgtggcctgccgcaacttctacctg gacggccggtgtgtggagacctgcccgcctccgtactaccacttccaggactggcgctgc gtgaacttcagcttctgccaggacctgcataacaagtgcaagaactcccggaagcagggc tgccaccagtacgtcattcacaacaacaagtgcatccccgagtgtccctccgggtacacc atgaactccagcaacctgatgtgcaccccgtgcctgggcccctgccccaaggtctgtcac ctcctagaaggcgagaagaccattgactcggtgacgtcggcccaggagctccgaggctgc accgtcgtcaacggcagcctgatcatcaacatcagaggaggcaacaacctggctgcagag ctggaggccaacctgggcctcatcgaagagatctcggggtatctcaaaatccgccgatcc tacgccctcgtgtctctttccttcttccggaagttacgcgtgattcgaggagagaccctg gaaatcgggaactactccttctatgccttggacaaccagaacctaaggcagctgtgggac tggagcaagcacaacctcaccatcactcagggcaaactgttcttccactacaaccccaaa ctctgcctgtcagaaattcacaagatggaagaagtttccggaaccaaggggcgccaggag aggaacgacatcgctccgaagaccaatggggaccaggcatcctgtgaaaatgagttactt aagttttctcacattcgaacttcctcggacaagatcttgctgaagtgggagccttactgg ccccccgacttccgagacctcttggggttcatgctcttttacaaagaggccccgtatcag aatgtgacagagttcgacgggcaggatgcgtgcggctccaacagctggacggtggtggac atcgaccccccgcagaggtccaatgaccccaagtcacagaaccagcccgggtggctgatg cggggcctgaagccctggacccagtacgccatctttgtcaagaccctggtcaccttctct gacgagcggcgcacctacggggccaagagcgacatcatttatgtccagacagacgccacc aacccttccgtccccctggacccgatctcggtgtctaattcctcatcccagattatcctg aagtggaagcccccctccgacccgaacggcaacatcacccactatctggtgttctgggag aggcaggcggaggacagcgagctgtatgagttggattattgcctcaaagggttgaagctg ccctcccggacatggtcgcccccgttcgagtctgaggattcgcagaaacacaatcagagc gagtacgaggactcggccggcgagtgctgctcctgccccaagaccgactctcagatcctg aaggagctggaggagtcctcgtttcggaagacgtttgaggattacctgcacaacgtggtc tttgtgcccagaaaaacctcgccaggcactggggccgaggacactaggccgtcacggaaa cgcaggtcccttggtgacgtggggaatgtgacggtggccatccccacagtcccgggattc cccaacacctcctcaaccagcgtgcccacgagccccgaggagcacaggcccttcgagaaa gtggtgaacaaggagtcgctggttatctcgggcctgcgtcacttcactgggtaccgcatc gaactgcaggcctgcaatcaagatgtccccgaggagaggtgcagcgtggctgtgtacatc agtgccaggaccatgcccgaagccaaggcggatgacatcgttggcccagtgacccatgaa atcttcgagaacaatgtcgttcacttgatgtggcaggggcccaaggaacccaatggtctg atcgtgctgtatgaagtgagttatcggcgatacggcgacgaggagctgcatctctgtgtc tcccgaaagcattatgctctggagcgaggctgcaggctgcgtgggctgtcaccagggaac tacagcgtgagagtccgggctacctccctggcaggcaatggctcctggactgaagccacc tatttctatgttacagactatttagacgtcccatcaaatattgccaaaattatcattggc cccctcatctttgtcttcctcttcagtgttgtgattggaagtatttatctattcctgaga aagaggcagccggacgggccgctggggccgctgtacgcgtcttcaaaccccgagtacctc agcgccagtgatgtatttccttgttctgtgtacgtgcccgacgagtgggaggtgcctcga gagaagatcaccctcctgcgagagctggggcaaggctccttcggcatggtgtacgagggc aacgccagggacattgtcaagggcgaggcggagacccgtgtggcggtgaagacggtcaac gagtcagccagtctccgcgagcggatcgagttcctcaacgaggcgtcggtcatgaagggg ttcacctgccaccacgtggtccgcctcctgggggtggtgtccaggggccagccgacactg gtagtgatggagctgatggctcacggagacctgaagagctatctccgttctctgcggcct gaagctgagaataacccgggtcgtcctccccctaccctgcaagagatgatccagatggca gcagagattgcggatgggatggcatacttgaatgccaagaagtttgtgcaccgggacctg gcagctcgaaactgcatggttgcccacgattttaccgtcaaaattggagactttggaatg accagagacatctatgaaacggattactaccggaaagggggcaagggtctgctccctgtg cggtggatggcaccagaatccctgaaggatggggtcttcactacttcttctgacatgtgg tcctttggtgtggtcctttgggagatcaccagcttggccgaacagccttaccaggggctg tctaatgagcaggtgttgaaatttgtcatggatggagggtatctggatcaacccgacaat tgtccagagagagtcactgacctgatgcgcatgtgctggcagttcaaccccaaaatgcga ccgaccttcctggagattgtcaacctgctcaaggacgacctgcaccccagctttccagaa gtttccttcttccacagtgatgagaacaaggctcctgagagcgaggagctagagatggaa tttgaggacatggaaagcgtccccctggaccagtcctcacactgtcagagggaggaggtg gggggccgggatggcgggtcctcactgggcctcaagcggaactatgaagagcatatcccc tacacccacatgaatggaggcaagaaaaatggacggattctgaccctgcctcggtcgaat ccttcctaa

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