Thermoactinomyces vulgaris: AB849_013105
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Entry
AB849_013105 CDS
T05864
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
tvu
Thermoactinomyces vulgaris
Pathway
tvu00860
Porphyrin metabolism
tvu01100
Metabolic pathways
tvu01110
Biosynthesis of secondary metabolites
tvu01120
Microbial metabolism in diverse environments
tvu01240
Biosynthesis of cofactors
Module
tvu_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
tvu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
AB849_013105 (cobA)
Enzymes [BR:
tvu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
AB849_013105 (cobA)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
AB849_013105 (cobA)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Radical_SAM
Motif
Other DBs
NCBI-ProteinID:
QBK14454
LinkDB
All DBs
Position
complement(2570552..2572069)
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AA seq
505 aa
AA seq
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MTGMVYLVGAGPWDPGLITVKGLKALKKADVIIYDRLANPQLLNHAKENVERIYVGKSSD
HHTHTQEEINDLLVEKAKQGLTVVRLKGGDPFVFGRGGEEAERCVEEGIPFEVIPGITSA
IAVPAYAGIPVTHRDMNASFSVVTGYERKEKNEPSVSFASLAKATETQVFLMGVKNLPYI
VERLRKYGRSGDTPVALIRWGTKMEQETLTGTLEDIVEKAEERKFRPPAVIVVGEVVRLR
EKLAWFEQKPLFGKRVLVTRAREQSQSLSEKIHELGGESLEFPVIKITRPKRQDFLDQSL
RRLHEYDWIIFTSVNGVKFFFSRLRELKIDIRQMGKAKIAAIGPKTAEALWEKGLLVDVI
PEEYQAEGLIESLRHQVKAGEKILLPRANIARKILAVKLAEMGCEVTDADAYDTETETGN
VSEIVEGLREGTIHVITFTSPSTVRNFVRSLQTVEKDVPSLLKGVHIVCIGPITAQTAGE
LGLKVDGIAKEYTIEGLVEVLKQLP
NT seq
1518 nt
NT seq
+upstream
nt +downstream
nt
atgaccggtatggtttatctggttggagcgggtccctgggatccgggcctgatcaccgtc
aagggattaaaggcgctgaaaaaagcggatgtgatcatttatgaccggttggccaacccc
cagcttttgaatcatgcaaaagagaatgtcgaacggatttatgtgggaaaatcatccgac
catcatacacacacccaggaagagatcaatgatctgctggttgaaaaggccaaacaagga
ttgacggtggtccggctgaaaggcggggatccttttgttttcggacgcggcggggaagag
gccgaacgttgcgtggaagaaggcattccttttgaagtgatccccggcatcacctctgcc
attgccgttccggcttatgcagggattccggtcacccatcgggatatgaatgcatcgttt
tcggtagtcaccgggtatgaacggaaagaaaaaaatgaaccctccgtttcttttgcttcc
ctggccaaagcaaccgaaacccaggtttttttgatgggggtcaaaaatcttccctatatc
gttgaacggttgagaaaatacggaagatccggcgatacgccggtggctttgatccgttgg
ggaaccaaaatggaacaggaaactttgaccggcacgctggaggatattgttgaaaaggcg
gaagaacgaaaattccgcccgccggcggtgattgtggtcggggaagtggtccgcctgcgt
gaaaagctggcatggtttgaacaaaaaccattgtttggcaaacgggttttagttacccgg
gcgcgtgagcaaagccaaagcttgtcggagaagattcatgaattgggaggagaatcgctg
gagtttccggtgatcaaaatcacccgcccgaaacgccaggactttcttgatcaatccctc
cgccgccttcatgagtatgattggattatctttaccagtgtcaacggggtgaaatttttc
ttttcgcgactgcgcgagttaaagatcgatatccgtcaaatgggcaaagcgaagatcgcc
gccatcggcccgaaaacggcagaagccttgtgggaaaaagggttgctcgttgacgtgatt
cccgaagaataccaggcggaagggttgattgaaagtcttcgccaccaagtcaaagcggga
gaaaaaatcttattgccccgtgccaacatcgcccgcaaaattttagcggtcaagctggct
gagatgggttgtgaagtgaccgatgccgatgcatatgacacggagacagaaactggaaat
gtgagtgaaatcgttgaggggttacgggaaggaacgattcatgtgattactttcacaagt
ccttccacggtccggaactttgtccggtccctgcaaacggtggaaaaagatgtgccttca
ttactaaaaggggtgcacattgtctgcatcggcccgattacggctcaaacggccggggaa
ttgggattgaaagtggacggcattgccaaagagtacaccattgaaggattggtggaagta
ttgaagcagttgccataa
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