KEGG   Tropheryma whipplei TW08/27: TW175
Entry
TW175             CDS       T00117                                 
Symbol
folP
Name
(GenBank) dihydropteroate synthase
  KO
K00796  dihydropteroate synthase [EC:2.5.1.15]
K00950  2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
K01633  7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]
Organism
tws  Tropheryma whipplei TW08/27
Pathway
tws00790  Folate biosynthesis
tws01100  Metabolic pathways
tws01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:tws00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    TW175 (folP)
Enzymes [BR:tws01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.81  7,8-dihydroneopterin oxygenase
     TW175 (folP)
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.15  dihydropteroate synthase
     TW175 (folP)
  2.7  Transferring phosphorus-containing groups
   2.7.6  Diphosphotransferases
    2.7.6.3  2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
     TW175 (folP)
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.2  Aldehyde-lyases
    4.1.2.25  dihydroneopterin aldolase
     TW175 (folP)
 5. Isomerases
  5.1  Racemases and epimerases
   5.1.99  Acting on other compounds
    5.1.99.8  7,8-dihydroneopterin epimerase
     TW175 (folP)
SSDB
Motif
Pfam: Pterin_bind HPPK FolB DUF2824 Phospholip_A2_4
Other DBs
NCBI-ProteinID: CAD66854
LinkDB
Position
216584..218881
AA seq 765 aa
MMNMSYTPDPFPPPNVMGILNITDDSFSDGGLFLDPSAAITQGRKLFAEGASIIDVGGES
TRPGAERISVEEEKKRVLPVVRELLSEGIHVSLDTMNADTAKEGLSMGVAIINDVSAGKA
DPDMLRVIADAGCKYIAMHWRGHSMFMDSLAHYDDVVSDVLRELKFDIERITAAGVKSDQ
IILDPGFGFSKTSDHNWQLFRNLDCFVKLGFPVLIGLSRKRFLSRVFKGHDFSPKDSKNV
GGLDNREILARDLPSGILSAIAITRGAWGVRVHDVASAHTALRTLQLAQYGSVYQAHKRA
ANTGIDTAIPGQGNTDDTTASSNHTNNSETGASLKSGVSQVRNMIAPPVIKIRSLRVYAY
HGVYRSERDYGQQFIIDADIQLKHFPEDKIDSTLDYDSLTGKFVQYATASSVNLIETLAD
HLAKIAVLDPMVEWVSLSITKPNPPLAYMKQSNTAACHAMHKPDTRGDYAKEHTNLTGLQ
LSCTVRKVRSESVTRVYIGIGANVGNCLDNVQRAIKDIADHPMIELVSLGRLFRTTAVVG
ESLDESLPVFLNTAIAIDTALSMQDLLALMLCIEKKLGRTRHSRTRHSLSSAQDAHQADS
TSDNPNQLHYPCAGRQGIQQPLHSSTLAHTQDGFVNRHIDLDILLAEGVQITEHGLCIPH
PRLSKRAFALLPLESIDPDLHIPGHGPITDLIHGLPEDQISSVATLRDSGYELFRHSITR
LNNCSAHNKAYVTPSAGQNYDSEQDFDAGLSHTESRGKTEPHGKI
NT seq 2298 nt   +upstreamnt  +downstreamnt
gtgatgaacatgagctatactcccgacccatttccacctcctaatgtaatgggcattctg
aatataaccgatgattctttcagtgatggtggactgtttttagacccctctgctgccatt
acccaaggtagaaagttatttgctgagggtgcttcaataatcgatgttgggggtgaatcg
acacgcccgggtgctgagcggattagcgtggaagaagaaaaaaaaagggttttacccgta
gttagggaacttctatccgaaggtattcatgtaagtcttgacaccatgaatgcagacaca
gcaaaagagggccttagcatgggtgttgccattataaatgacgtatcagcgggcaaagcc
gacccggacatgctaagagtgatagccgatgcaggctgtaaatacatcgcgatgcattgg
cgtgggcactccatgtttatggatagccttgctcattacgacgatgttgtgagtgatgtt
cttcgagagcttaagtttgatatcgagcgtattactgccgctggggtaaagagcgaccag
atcatccttgatcctggttttggcttttctaaaacaagtgaccataattggcagttgttc
agaaaccttgattgctttgttaagctgggctttcccgtgctgattggtctttcgcgcaag
aggtttttgagtcgagtatttaaggggcatgatttttctcctaaagattctaagaatgtt
ggagggttggataaccgcgaaatacttgcgcgcgatctgccaagcgggatactgagtgct
attgccataacacgtggagcatggggcgtgcgtgtacatgatgttgcctcagctcacacg
gcgctgcggactctacagcttgcgcaatacggctcggtatatcaggcccacaaacgggcg
gcaaataccggaatagacaccgcaatacccggccaaggcaacactgatgacaccactgcc
tccagtaaccacaccaacaattctgaaacaggagcttctttaaaaagtggcgtgagtcaa
gtccgcaacatgattgccccgcccgttataaagataagaagtctgcgcgtgtatgcatat
catggggtgtatcgttctgagcgggactacggtcagcaattcattatcgatgcagatatt
caattaaaacattttccagaagacaagattgactcaaccctagactatgactcattgact
ggaaagtttgtgcaatatgccaccgcatcatctgtgaatcttattgagacactcgctgat
caccttgcaaagattgccgtcctagatccaatggttgagtgggtaagcctcagcataaca
aagccaaaccctccgctcgcttatatgaaacaaagtaacacagccgcctgtcatgctatg
cataaacctgataccagaggtgattatgctaaagaacacacaaatcttacaggccttcaa
ttatcgtgcacggttaggaaagtgcgttccgaaagtgtaacaagggtctatataggcatc
ggtgcaaatgtaggtaattgcctggataatgtccagcgcgcgatcaaggatattgcagat
catccaatgattgaacttgtctcactcggcaggcttttccgaaccaccgccgttgttggc
gagagtcttgatgaatctctaccggtatttttgaatactgcaatcgcaatcgatactgct
ttatccatgcaggatttgcttgccttaatgctttgtatagagaaaaagcttggaagaact
cgtcacagtagaactcgtcacagtttatcttccgctcaagacgcccaccaggctgattca
actagcgataatcctaaccagttacattatccttgtgccggacgccaaggcatccaacag
cctttacattcgtcaactttggcgcacactcaggatgggtttgttaatcggcatattgac
cttgatatcctgctcgcggagggggttcaaattactgaacacgggttatgtattccacat
ccaaggctcagtaagagagcctttgcgcttttgccacttgagagtatagatcctgatctg
catatccccggacatggcccaattactgacttgatacatggtcttcctgaggatcaaata
agctctgttgctacccttcgagattccgggtatgaattattcaggcactctattaccaga
ctaaacaattgttcagcgcataataaagcgtatgttactccgtcagcgggccagaattat
gattctgaacaggattttgatgctggattgtcacacacagaatcacgcggaaaaacagag
ccacacggaaaaatatga

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