KEGG   Ursus arctos horribilis (North American brown bear): 113241758
Entry
113241758         CDS       T05909                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
uah  Ursus arctos horribilis (North American brown bear)
Pathway
uah04010  MAPK signaling pathway
uah04022  cGMP-PKG signaling pathway
uah04137  Mitophagy - animal
uah04141  Protein processing in endoplasmic reticulum
uah04151  PI3K-Akt signaling pathway
uah04210  Apoptosis
uah04211  Longevity regulating pathway
uah04261  Adrenergic signaling in cardiomyocytes
uah04668  TNF signaling pathway
uah04720  Long-term potentiation
uah04722  Neurotrophin signaling pathway
uah04725  Cholinergic synapse
uah04728  Dopaminergic synapse
uah04911  Insulin secretion
uah04912  GnRH signaling pathway
uah04915  Estrogen signaling pathway
uah04918  Thyroid hormone synthesis
uah04922  Glucagon signaling pathway
uah04925  Aldosterone synthesis and secretion
uah04926  Relaxin signaling pathway
uah04927  Cortisol synthesis and secretion
uah04928  Parathyroid hormone synthesis, secretion and action
uah04932  Non-alcoholic fatty liver disease
uah04934  Cushing syndrome
uah04935  Growth hormone synthesis, secretion and action
uah05010  Alzheimer disease
uah05012  Parkinson disease
uah05014  Amyotrophic lateral sclerosis
uah05020  Prion disease
uah05022  Pathways of neurodegeneration - multiple diseases
uah05030  Cocaine addiction
uah05031  Amphetamine addiction
uah05034  Alcoholism
uah05161  Hepatitis B
uah05163  Human cytomegalovirus infection
uah05166  Human T-cell leukemia virus 1 infection
uah05203  Viral carcinogenesis
uah05207  Chemical carcinogenesis - receptor activation
uah05215  Prostate cancer
uah05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uah00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    113241758 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    113241758 (ATF4)
   04668 TNF signaling pathway
    113241758 (ATF4)
   04022 cGMP-PKG signaling pathway
    113241758 (ATF4)
   04151 PI3K-Akt signaling pathway
    113241758 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    113241758 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    113241758 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    113241758 (ATF4)
   04922 Glucagon signaling pathway
    113241758 (ATF4)
   04912 GnRH signaling pathway
    113241758 (ATF4)
   04915 Estrogen signaling pathway
    113241758 (ATF4)
   04926 Relaxin signaling pathway
    113241758 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    113241758 (ATF4)
   04918 Thyroid hormone synthesis
    113241758 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    113241758 (ATF4)
   04925 Aldosterone synthesis and secretion
    113241758 (ATF4)
   04927 Cortisol synthesis and secretion
    113241758 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    113241758 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    113241758 (ATF4)
   04728 Dopaminergic synapse
    113241758 (ATF4)
   04720 Long-term potentiation
    113241758 (ATF4)
   04722 Neurotrophin signaling pathway
    113241758 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    113241758 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    113241758 (ATF4)
   05203 Viral carcinogenesis
    113241758 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    113241758 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    113241758 (ATF4)
   05161 Hepatitis B
    113241758 (ATF4)
   05163 Human cytomegalovirus infection
    113241758 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    113241758 (ATF4)
   05012 Parkinson disease
    113241758 (ATF4)
   05014 Amyotrophic lateral sclerosis
    113241758 (ATF4)
   05020 Prion disease
    113241758 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    113241758 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    113241758 (ATF4)
   05031 Amphetamine addiction
    113241758 (ATF4)
   05034 Alcoholism
    113241758 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    113241758 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    113241758 (ATF4)
   04934 Cushing syndrome
    113241758 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:uah03000]
    113241758 (ATF4)
Transcription factors [BR:uah03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    113241758 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 DUF4407 MCU AAA_13 Nop53 bZIP_Maf Laminin_II DUF3450
Other DBs
NCBI-GeneID: 113241758
NCBI-ProteinID: XP_026335379
LinkDB
Position
Unknown
AA seq 351 aa
MAEMSFLNSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
WLAVDGLVSASDNGKEDAFSGTDWMVEKMDLKEFDFDSLFSIDDLETMPDELLATLDDTC
DLFDPLVQETNKEPPQSVNPIGHLPESLPKTDQIAPFTFLQPLPLSPGALSSTPDHSFSL
ELGSEVDISEGDRKSDSTAYITVIPQCIKEEDAPSDNDSGICMSPESYLGSPQHSPSTSR
GSPNRSLLSPGSHCGSARPKPYDPPGEKTAAKVKVEKLDKKLKKMEQNKTAATRYRQKKR
AEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKAREKKRVP
NT seq 1056 nt   +upstreamnt  +downstreamnt
atggccgagatgagtttcctgaacagcgaggtgttggtgggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaggagagcctgggtctcttagacgactacctggaggtg
gccaagcacttcaaacctcatgggttctccagcgacaaggctaaggcgggctcctccgaa
tggctggctgtggatgggttggtcagtgcctcagacaacggcaaggaggatgccttttcc
gggacagattggatggtggagaaaatggatctgaaggagtttgattttgattctctgttc
agtatagatgacctggaaaccatgccagatgagcttttggccacgttggatgacacgtgt
gatctctttgaccccctagtccaggagacgaataaggagcccccccagagcgtgaaccca
attggccatctcccagaaagtttaccaaaaacagaccagattgccccctttaccttcctg
caaccacttccactttccccaggggccctgtcctccactccagatcattcttttagttta
gagctaggcagtgaagtggatatttctgaaggagatagaaagtcagactctactgcctac
attaccgtgatccctcagtgcataaaggaggaggatgccccctcagataatgacagtggc
atctgtatgagtcctgagtcctatctggggtccccccagcatagtccctctacctccagg
ggctctccaaataggagcctgctgtctccaggttcccattgtggttctgcccgccccaaa
ccctatgaccctcctggagagaagacggcagcaaaagtaaaggtcgagaaactagataag
aagctgaaaaagatggagcagaacaagactgcagccactaggtaccgccagaagaagagg
gcagagcaggaggccctcactggcgagtgtaaagagctggaaaagaagaatgaggctctg
aaagagagggcagattctttagctaaggagatccagtatctgaaagatttgatagaagag
gtccgaaaggcaagggagaagaaaagggtcccctag

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