Ursus arctos horribilis (North American brown bear): 113242248
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Entry
113242248 CDS
T05909
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
uah
Ursus arctos horribilis (North American brown bear)
Pathway
uah00010
Glycolysis / Gluconeogenesis
uah00020
Citrate cycle (TCA cycle)
uah00620
Pyruvate metabolism
uah00785
Lipoic acid metabolism
uah01100
Metabolic pathways
uah01200
Carbon metabolism
uah01210
2-Oxocarboxylic acid metabolism
uah04066
HIF-1 signaling pathway
uah04922
Glucagon signaling pathway
uah05230
Central carbon metabolism in cancer
uah05415
Diabetic cardiomyopathy
Module
uah_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
113242248 (PDHA1)
00020 Citrate cycle (TCA cycle)
113242248 (PDHA1)
00620 Pyruvate metabolism
113242248 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
113242248 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
113242248 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
113242248 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
113242248 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
113242248 (PDHA1)
Enzymes [BR:
uah01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
113242248 (PDHA1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
113242248
NCBI-ProteinID:
XP_026336007
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLRYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAHCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctcgccgctgtctctcgcgtgttgtcgggcgccgcccagaagccggca
agcagagttctcgtggcttcccgtaattttgcaaatgatgctacattcgaaattaagaaa
tgcgatcttcaccggctagaagagggcccccctgtcaccacagtgctcaccagggaggac
gggctcaggtactataggatgatgcagactgttcgccggatggagttaaaggcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaggccggcataaatcccacagaccatcttatcacagcctatcgggct
catggctttacctttactcgtgggctttctgtccgagaaattctcgcagagcttacagga
cgaagaggaggctgtgctaaagggaaaggtggatcgatgcatatgtatgccaagaacttc
tatgggggcaatggcatcgttggagctcaggtgcccctgggagcggggattgctctggcc
tgtaagtataatggaaaggatgaggtctgtttgactttatatggcgatggtgctgctaat
cagggtcagatatttgaagcttataacatggcagctttgtggaaattgccatgtattttc
atctgtgagaataaccgctatggaatgggaacgtccgttgagagagcagcggccagcact
gattactacaagagaggcgacttcattcctggactgagggtcgatggaatggatatcttg
tgtgtccgggaggcaacaaggtttgcagctgcccactgtagatctggaaaggggcccata
ctgatggagctacagacttaccgttaccatggacacagcatgagcgaccctggagtcagt
taccgtacgcgagaagagattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaacagcaatctggccagtgttgaagaattaaaggaaattgatgtt
gaagtgaggaaggaaattgaggatgctgcccagtttgccactgctgatcctgaaccgcct
ttggaagaactaggctatcacatttacagcagcgacccgccttttgaagttcggggtgca
aatcagtggatcaagtttaagtccatcagttaa
DBGET
integrated database retrieval system
