Ursus arctos (brown bear): 113264133 Help Entry 113264133         CDS       T05909                                  Symbol HK3 Name (RefSeq) hexokinase-3   KO K00844   hexokinase [EC:2.7.1.1] Organism uah  Ursus arctos (brown bear) Pathway uah00010   Glycolysis / Gluconeogenesis uah00051   Fructose and mannose metabolism uah00052   Galactose metabolism uah00500   Starch and sucrose metabolism uah00520   Amino sugar and nucleotide sugar metabolism uah00524   Neomycin, kanamycin and gentamicin biosynthesis uah01100   Metabolic pathways uah01200   Carbon metabolism uah01250   Biosynthesis of nucleotide sugars uah04066   HIF-1 signaling pathway uah04910   Insulin signaling pathway uah04930   Type II diabetes mellitus uah04973   Carbohydrate digestion and absorption uah05230   Central carbon metabolism in cancer Module uah_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate uah_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose uah_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:uah00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     113264133 (HK3)    00051 Fructose and mannose metabolism     113264133 (HK3)    00052 Galactose metabolism     113264133 (HK3)    00500 Starch and sucrose metabolism     113264133 (HK3)    00520 Amino sugar and nucleotide sugar metabolism     113264133 (HK3)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     113264133 (HK3)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     113264133 (HK3)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     113264133 (HK3)   09154 Digestive system    04973 Carbohydrate digestion and absorption     113264133 (HK3)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     113264133 (HK3)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     113264133 (HK3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:uah04131]     113264133 (HK3) Enzymes [BR:uah01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      113264133 (HK3) Membrane trafficking [BR:uah04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     113264133 (HK3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  113264133 NCBI-ProteinID:  XP_057168334 EnsemblRapid:  ENSUARG00005009778 LinkDB All DBs Position Unknown AA seq 954 aa AA seqDB search MRHIEREELKPEESDQLLLLPGGHPPLWNHMDSIGPVGLQQREGAPGCSQEGLPCPSDSS ELVLECLQQFKVTETQLQQIQASLLGSMEQALRGQATPASAVRMLPTYVGSTPHGTEQGD FVVLELGATGASLRVLWVTLMGTEGHRMEPQSQEFVIPPEVMLGPGQQLFDFAAHCLSEF LDALPMDKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGHDVVQLLRDAIERQG AYSIDVVAVVNDTVGTMMGCEPGVGPCEVGLVVDTGTNACYMEEARHVAVLDEDRGRVCI SVEWGSFSDDGVLGPVLTTFDHALDRESLNPGAQRFEKMIGGLYLGELVRLVLAHLAQRG VLFGGCTSPALLSRGSILLDHVAEMEDPLAGAARVHALLQDLGLSVGASDAELVQYVCAA VLTRAARLCAAALAAVLSRLQHSREQQMLQIAVATGGRVFERHPSFLSVLQKTVMLLAPQ CDVSFIPSVDGGGRGVAMVTAVAARLAAHRRLLEETLAPFRLNHNQLAAVQAQMREAMVK GLRGEASSLRMLPTYVRATPDGTERGDFLALDLGGTNFRVLLVRVTAGGVKITSQVYSIP EDVAQGSGQQLFDRIVDCIVDFQQKQGLSGQSLPLGFTFSFPCRQLGLDQGILLNWTKGF SASDCEGQDVVCLLREAIGRRQAVELNVVAIVNDTVGTMMSCGYEDPRCEVGLIVGTGTN ACYMEELRNVAAVAGDSGHMCINMEWGAFGDDGSLDLLRTCFDANVDQASINPGKQSFEK MISGMYLGEIVRHILLRLTSLGVLFRGQQTQRLQTRDIFKTKFLSEIESDSLALRQVRAI LEDLGLPLTSDDALMVLEVCQAVSQRAAQLCGAGVAAVVEKIRENRGLEELTVSVGVDGT LYKLHPHFSGLVAATVRELAPRCAVTFLQSEDGSGKGAALVTAVACRLAQMARV NT seq 2865 nt NT seq  +upstreamnt  +downstreamnt atgcgtcacattgagagagaagagctcaagcctgaggaaagtgaccaactgctgcttctc ccgggtggccaccctccattgtggaaccacatggactccattgggccagtagggttgcag caaagggaaggagctcctggctgctcccaggagggcttgccctgcccctcagacagctct gagctggtgctggagtgtctacagcaattcaaggtgacggagacacagctgcagcagatc caagccagcctcctgggctctatggagcaggcactgcgggggcaggccacccctgcctct gctgtccggatgctgcccacatacgtggggtccaccccacacggcactgagcaaggagat tttgtagtgctggagctgggggctacaggggcctcactgcgtgttctgtgggtgaccctg atgggcactgagggtcataggatggagccccagagccaggagtttgtgatccccccagag gtgatgctgggtcctggtcagcagctctttgactttgctgcccactgtctgtctgagttc ctggatgcactccccatggacaaacagggtctgcagcttgggttcagcttctccttccct tgtcaccagacgggcctggacaggagcacccttatttcctggaccaaaggttttaggtgc agtggtgtggaaggccatgatgtggtccagttgctgcgagatgccatcgagaggcagggg gcctacagcatcgatgtggttgccgtggtgaatgacacagtgggcaccatgatgggctgt gagccaggggttgggccgtgtgaagtcgggcttgttgtagacactggcaccaatgcatgt tacatggaggaggcaaggcatgtggcagtgctggatgaggaccggggccgcgtctgcatc agcgttgagtggggctccttcagtgatgatggggtcctgggaccagtgctgaccaccttt gaccatgccttggaccgagagtccctgaatcctggtgcccagaggtttgagaagatgatt ggaggcttgtacctgggtgagctggtgaggcttgtgttggctcacctggcccagcgaggg gtcctctttggtggctgcacctcccctgccctgctgagccgaggcagcatcctcctggat catgtggctgagatggaggaccccttggctggggcagcccgtgtgcatgctctcctgcag gacttgggcctgagcgtgggggcctcggatgctgagctcgttcagtacgtatgtgcagcc gtgttgactcgggctgcccggctctgtgccgccgccctggctgctgttctctcccgcctc cagcacagccgggagcagcagatgcttcagattgctgtggccaccggaggccgagtgttt gagagacaccccagtttcctcagcgtcctgcagaagactgtgatgctcctggccccccaa tgtgatgtctccttcattccctctgtggatgggggtggccggggcgtggcaatggtgact gctgtggctgcccgtctggctgctcaccggcgcctgctggaagagaccttggcacctttc cggttgaaccataatcagctggcagcagtgcaggcacagatgcgggaggcaatggtcaag gggctccgaggggaggcctcatccctccgcatgctgcccacttatgtccgggccacgcct gatggcactgagcgtggggacttcctggccctggacctggggggcaccaacttccgggtg ctcttggtgcgcgtgacagcaggaggtgtgaagatcaccagccaggtctactccatcccg gaggatgtggcccagggctctggacagcagctcttcgaccgcatcgtggactgcattgtg gacttccagcagaagcagggcctgagtgggcagagccttccgctgggtttcaccttctcc ttcccatgcaggcagctcggcctcgaccagggcatcctcctaaactggacaaaaggtttc agtgcatcagactgtgagggccaagatgttgtgtgtctgctgcgggaagccatcgggcga agacaggcagtagagctgaatgtggttgccattgtcaatgacacggtggggaccatgatg tcctgtggctatgaggatccccgttgcgaggtcggcctcatcgttggaactggcaccaat gcctgctacatggaggagcttcggaatgtggcagctgtggctggggactcaggccacatg tgcatcaatatggaatggggtgcctttggggatgatggctctttggacttgcttagaacc tgctttgatgcaaatgtggaccaggcatccatcaaccctggcaagcagagctttgagaag atgatcagtggcatgtacctaggggagatcgtccgccacattctcttgcgtttgaccagc cttggagttctcttccggggccagcagacccagcgccttcagaccagggacattttcaag accaagtttctctctgagattgaaagtgacagcctggctctgaggcaggtccgagccatc ctggaggatctggggctgcccctgacctcagatgatgccctgatggtcctggaggtgtgc caggctgtgtcccagcgggctgcccagctctgtggggcgggtgtggctgctgtggtggag aagatccgtgagaaccggggcctggaagagctgactgtgtccgtaggggtggatgggacc ctctacaagctgcacccccacttctccggcctggtggcagccacggtgagggagctggcc cctcgctgtgcggtcaccttcctgcagtcggaagatgggtccggcaaaggtgcagccctg gtcactgcagttgcctgccgtcttgcccagatggcccgtgtttga

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