Vibrio campbellii ATCC BAA-1116: M892_12385
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Entry
M892_12385 CDS
T02837
Symbol
metL
Name
(GenBank) bifunctional aspartate kinase II/homoserine dehydrogenase II
KO
K12525
bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:
2.7.2.4
1.1.1.3
]
Organism
vca
Vibrio campbellii ATCC BAA-1116
Pathway
vca00260
Glycine, serine and threonine metabolism
vca00261
Monobactam biosynthesis
vca00270
Cysteine and methionine metabolism
vca00300
Lysine biosynthesis
vca01100
Metabolic pathways
vca01110
Biosynthesis of secondary metabolites
vca01120
Microbial metabolism in diverse environments
vca01230
Biosynthesis of amino acids
Module
vca_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
vca_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
vca_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
vca00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
M892_12385 (metL)
00270 Cysteine and methionine metabolism
M892_12385 (metL)
00300 Lysine biosynthesis
M892_12385 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
M892_12385 (metL)
Enzymes [BR:
vca01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
M892_12385 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
M892_12385 (metL)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
ELFV_dehydrog
Motif
Other DBs
NCBI-ProteinID:
AGU95191
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All DBs
Position
I:2667803..2670211
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AA seq
802 aa
AA seq
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MSVQRQLHKFGGSSLANPECYQRVVTILKEYSAENDLVVVSAAGKTTNRLIEFLEGLDKD
GRIAHEALQSLRQFQTELVEALLEGEVQAQLLASLQDEFSTLAELTAPLTETQKAAVLGH
GEVWSSRLLAALLSQQDLPAVAQDSRVFLRAEAGTQPEVDRARSYVLIKEALAQHSHKRV
IITGFMAQNEAGETVLLGRNGSDYSATVIGALAEVNSVTIWSDVAGVYSADPRLVSDACL
LPLLRLDEASELARLAAPVLHSRTLQPVAQSAMDLNLKCSYQPESGSTRIERVLASGRGA
KIITSLDEVLLVQLSFIHGHDFERAQKEVLQALKRAQLEPLAFEAQEDQQTLRLAYTAEI
AGGALTYLQELAVEAEIKLKEGYSLLAAVGAGVTKNANHCFGFYQQLKHAPVEFISETES
GLSLVAVLRRAEVEELVQSIHSQLFQAQKRVAVALCGKGNIGSSWLSLFAEQKEELEKRH
GMSFDLVAVVDSQTYWFDENGIDAATVAQRFDDESTENDGNWLAKLGAIQNFDEAVVLDV
TASKELATRYVEIAQQGIHLISANKVAGSADSQYYHQVQDAFAKIGRHWLYNATVGAGLP
INHTVRDLRESGDDIVALSGIFSGTLSWLFQQFDGSVPFAELVDLAWQQGLTEPDPRSDL
DGSDVMRKLVILARESGLDIEPENVKVESLVPAELRDLSLDAFFDQGDILSEILQERLTK
AQRNDQVLRYVARLERNGKATVGVEALSREHALANLLPCDNIFAIESKWYKDNPLVIRGP
GAGCEVTAGAIQSDLNRLAGLF
NT seq
2409 nt
NT seq
+upstream
nt +downstream
nt
atgagtgtacaacgtcagctgcataaatttggcggcagcagcttagcgaaccccgagtgc
taccagcgcgtggtaactattcttaaagagtattcggcagaaaatgacttggtggtggtc
tctgcggcagggaaaaccaccaaccgcttgatcgagtttttagaaggcttagataaagat
ggccgcattgcccatgaagccttgcagagcttgcgacagttccaaactgaattggtagaa
gctttactagaaggtgaagttcaagcgcaactgcttgcttctcttcaagatgaattcagt
accttggcagagttaacagcgccactaaccgaaacacaaaaagcggcggttttaggtcat
ggcgaagtatggtcctcacgcttactggctgcgctgttatcacagcaggatctgccagca
gtagcgcaagattcacgtgtctttctgcgtgcggaagctggcacacagccagaggttgat
cgtgctcgttcatatgtattgattaaagaagcgttggctcaacacagccataaacgcgtc
attattactggctttatggcgcaaaacgaagcgggtgagacagtattgcttggacgcaat
ggttcagactactcagcaaccgtgattggtgctttagctgaagttaattcggtgaccatc
tggagtgacgtggctggcgtttacagcgcagatcctcgtttggtatcggatgcttgcctg
ctccctctattgcgcttggatgaagcgagtgagctggctcgtcttgctgcgccggtgtta
cacagtcgtacacttcagcctgtggctcaaagcgcgatggatttgaacctaaaatgcagc
taccagccagagtctggctcaacacgaatcgaacgtgtattggcatccggccgcggtgca
aaaatcattacctctcttgatgaagtgctattggtgcagctgtcttttatccatggtcac
gattttgagcgagcgcagaaagaagttctgcaggcgctaaaacgtgctcaattggagcct
ttagcattcgaagcacaagaagatcagcagaccttacgtttagcctacaccgcagagatt
gctggcggcgcattaacctatctgcaagagttggccgttgaagcggaaatcaaactgaaa
gaaggctattcactactggctgccgtcggtgccggtgtgacgaaaaatgcgaatcactgc
tttggtttttatcagcaattgaaacacgctccggtggagtttatttcagagacggaatct
ggcttgagtttggtcgccgtgttgcgtcgcgctgaagtcgaagagctagtacaaagtatt
catagccaattgtttcaagcgcagaagcgcgtagcggtggctttgtgtggaaaaggcaat
attgggtcaagttggttatcactgttcgcagagcaaaaagaagagctcgaaaaacgtcac
ggcatgagctttgacttggtagcggttgtcgacagccaaacgtactggtttgatgaaaac
ggtattgatgccgcgacggttgctcagcgttttgatgacgaaagcacagagaatgatggc
aactggctggcaaagcttggtgcgatacaaaactttgatgaagccgtggtactggatgtt
acggcaagtaaagagctggcgacacgttatgtggaaatcgcacagcaaggcattcaccta
atttcggcgaacaaagtagcaggttcggcggacagtcagtactaccatcaagtacaagac
gcgtttgctaaaattggccgccattggttgtacaatgcgaccgttggtgcaggactacca
atcaaccataccgttcgagatttacgtgaaagtggtgatgatatcgtcgcactatcaggc
atcttctccggtacgttatcgtggttattccaacagtttgacggttcggtaccttttgct
gagcttgttgatttagcatggcaacagggcttgactgagcctgaccctcgttctgacctt
gatggttctgatgtgatgcgtaagctggtcatcttagcgcgagaatctggtttggatatt
gaaccagagaacgtgaaagtagagtcgctggtgccagcagaattgcgagacttgagccta
gacgctttcttcgaccaaggagatattctcagcgagattcttcaagaacgtttgaccaag
gcgcagagaaacgaccaagtgctgcgttatgtggctcgtctagagcgtaatggcaaagcc
acagtaggcgttgaagcgttatcacgtgaacatgctttagcgaatttgctgccatgtgac
aatatcttcgccattgagagtaaatggtacaaagacaatccactagtgattcgtgggcca
ggtgcaggatgtgaagtaaccgcaggggccattcaatcagacctgaatcgcttggctggt
ttgttctga
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