Vibrio japonicus: NP165_14530
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Entry
NP165_14530 CDS
T08510
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
vjp
Vibrio japonicus
Pathway
vjp00280
Valine, leucine and isoleucine degradation
vjp00640
Propanoate metabolism
vjp00785
Lipoic acid metabolism
vjp01100
Metabolic pathways
vjp01110
Biosynthesis of secondary metabolites
vjp01210
2-Oxocarboxylic acid metabolism
Module
vjp_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
vjp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
NP165_14530 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
NP165_14530 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NP165_14530 (pdhA)
Enzymes [BR:
vjp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
NP165_14530 (pdhA)
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Motif
Pfam:
E1_dh
Transketolase_C
Transket_pyr
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
PFOR_II
Motif
Other DBs
NCBI-ProteinID:
UUM32777
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Position
2:280463..282490
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AA seq
675 aa
AA seq
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MNKRLHINRQHLLDQLEKMLRIRRFEEKCAELYAMEKIRGFLHLYIGEEAIAVGVMSALN
PDDQVVATYREHGHALARGLSMDSVLAEMYGRANGCSHGRGGSMHLFDKNLRFYGGNAIV
GGGLPLATGLAMANKKMHRDDIAVCFFGEGAVAEGEFHESLNLAALWNLPVLFVCENNRY
AMGTALALSESETNIAQKAKSYGIEAAQVDGMNVVDVEAAASEAVDFIRQNQKPYFIECQ
TYRFRGHSSFDTQLYRDKSEVALWEEKGPVKQLILWLKENNHFQDNELTAIESKIAQEIN
DAIAFAENGEWEPEEHLTRFVHSPKTQPPASPIPSSQAPATLTYREALRAGISDVLISEP
RAFLMGEDVGRYGGCYAVSKGLFDQFGADRIIDTPLCESGFVGVGVGAALGGLRPIVEVM
TVNFSLLAMDQIINTAATLLHMSGGQFNVPIVIRMACGAGKQLAAQHSHSWENFYAHVPG
LKVLSPATHNDARYMLSQAMIDPDPVLIFEHVMLLNEEGPVSAEPDAPMNQALVRRAGTD
VTLITYGGSLSKTLQAAEQLASEGIDAEVVDLRSLRPLDTPTIIASVSKTHRAVINDEGW
YTGSLAGEVSSIIMENAFWQLDAPVQRVCTQEVPIPYPHHLEQAALPQCDKIVAAAKATL
VLPNWQTNERKPDNG
NT seq
2028 nt
NT seq
+upstream
nt +downstream
nt
atgaataaaaggcttcatatcaaccgccaacatctactcgaccagcttgaaaaaatgctc
cgtatccgccgctttgaagaaaagtgcgccgagctgtacgccatggagaaaattcgcggt
tttcttcatctatatatcggtgaagaggcgatagccgtcggcgtgatgtcggcgctcaac
ccagacgaccaagtcgttgccacgtatcgcgagcatgggcatgcgctcgcccgtgggctg
agtatggatagcgtcttggcagaaatgtacggccgcgcgaacggttgcagccacgggcgc
ggcggctcgatgcacctatttgataaaaacttacgcttttacggtggcaacgccattgtc
ggcggagggctacccctcgccacagggctcgccatggccaataagaaaatgcaccgagac
gacatcgcggtgtgcttttttggcgaaggcgctgtggccgaaggggaatttcacgaaagc
ctcaacttagctgcgctgtggaatcttcctgtcctttttgtgtgtgaaaacaaccgctac
gccatgggcacagcactcgcgctttccgaatccgaaaccaatatcgctcaaaaagccaaa
agctacggcatagaagccgcccaagtcgatggcatgaacgtggtggatgtggaagccgct
gcctctgaagcggtcgattttattcgccagaatcaaaagccttatttcattgaatgccaa
acctatcgctttcgagggcattcgagttttgatactcaattgtatcgcgataaaagtgag
gtcgccctgtgggaagagaaaggcccagtaaaacagctgatcttatggctgaaggagaac
aaccacttccaagataacgaactgaccgccatcgaaagcaaaattgcgcaagagatcaac
gacgccatcgcgtttgccgagaatggcgagtgggaacccgaagagcacctgactcggttt
gttcatagccccaaaacccagccccctgctagcccgataccgtcaagccaagctcctgct
acccttacctatcgagaagcattacgcgcaggcattagcgatgtactaatcagtgaacca
cgcgcctttctcatgggtgaagacgtcggccgttatggcggctgctacgcggtcagcaaa
gggttgtttgaccaatttggagcagacaggatcatagacactccactctgcgagtctggc
tttgtaggcgttggggttggcgcggcactgggtgggctgcgcccgattgtcgaagtgatg
acggtgaactttagcttgctcgccatggatcaaatcattaataccgccgcgaccttactg
cacatgtcgggcgggcagtttaacgtcccgatagtgatccgaatggcgtgtggcgcaggc
aaacagcttgctgcgcagcactcgcacagttgggaaaatttctatgctcatgttccgggc
ttaaaagtgcttagccccgcaacacacaatgacgctcgctacatgctctctcaagcgatg
atagacccagaccctgtgctcatttttgaacatgtcatgctgctgaatgaagaaggacca
gtaagcgcagagcccgatgccccaatgaaccaagcgctggtgcgccgcgcaggtacagac
gttactctgatcacctacggcggcagccttagcaaaaccttgcaagccgctgagcaactg
gccagcgaaggcattgacgccgaagtggtagaccttcgctctctccgaccgctggataca
ccaaccatcattgcgagcgtcagtaaaacccaccgcgccgttatcaatgacgagggctgg
tacacgggcagcctcgcgggcgaagtcagttcgattattatggaaaacgcgttttggcag
ttggatgcccccgttcaacgcgtttgcacccaagaagttccgattccctatcctcatcat
ctagaacaagccgctcttcctcagtgtgacaaaattgtggctgcagccaaagccacactc
gtgcttcccaattggcaaacaaacgaacggaagccagacaatggataa
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