Varanus komodoensis (Komodo dragon): 123032623
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Entry
123032623 CDS
T07701
Symbol
ASH1L
Name
(RefSeq) histone-lysine N-methyltransferase ASH1L isoform X1
KO
K06101
[histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:
2.1.1.354
]
Organism
vko
Varanus komodoensis (Komodo dragon)
Pathway
vko00310
Lysine degradation
vko01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
vko00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
123032623 (ASH1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
vko03036
]
123032623 (ASH1L)
Enzymes [BR:
vko01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.354 [histone H3]-lysine4 N-trimethyltransferase
123032623 (ASH1L)
Chromosome and associated proteins [BR:
vko03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
123032623 (ASH1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SET
BAH
AWS
Bromodomain
PHD_5
PHD
Motif
Other DBs
NCBI-GeneID:
123032623
NCBI-ProteinID:
XP_044304599
Ensembl:
ENSVKKG00000008406
LinkDB
All DBs
Position
Unknown
AA seq
3033 aa
AA seq
DB search
MDPQNTAMLGLGSGSEGFSGKSPSAVGAGATGGRREAEVDGSAKEEEEKKRSREGSAGDE
AGKDEGAADAQQQFSVKETNFSEGNLKLKIGLQAKRTKKPPKNLENYVCRPAIKTTIKQP
RKVPKVGKMTDEKSDPSPPQPDPSKLYKKGGEAPGLVENSTSEGRTRESSPFSKKLSPLH
SEVTEYAKSALSTPVSSRDPDPKDRAQINGTPTVTEKLAHLIATCPPSKSSKTKQKKPPT
GIASGFAKDSGKKLATVGTATASISKDFVKKQPGCSSMGVALVNKEFAKKSPGTSNSTGL
IGKDSGSKKPPGPCPGMVGLVSKDCGKKLPVLTSPVGLVSKESVRRPLVTGMSVGPVSKE
SGKRLLGTSSPIGLVNKDSGKKLGLVSPPGLINKEPGKKFPVPCSPIRLFNKDAGKKQLG
ADGQTGLISKDSGKKLPGFGASSGLVNKDSGKKPLGANSPIGLITKESGKKPLGVGIPAT
LTAKDSGKKLAGASSLCGLANKDLGTLKADAASPSSEPFKRCCGASLTRLESPAPPGLLK
DNVGSKPFEKHVARQSKESLPEKLPVQKDAPGGVKDGGCIQQDSSAASERGASEAPKHDK
QLPVYCTSPDFRTSGGASDVSTAKSPFSAVGEGGLPSPSPAASVTTLTRSPTSTLAQLAS
NPLHLNNTPELLEGISEQISKTPFASDGARSSMSRPLNPGSHAPGKGAGREANHSGAAHP
DDPKPNPAVSKKPVLVPESGIRPSTAPSVVSFSSLFNSKPFLKIGSMTSSGKSCQGVDSL
SSTSGGSQAKPLKKRKGRKPRWTKVVSRSSCRPSKGLELGRPELFRNLSCSTLSSSCLDQ
AKLFKSTGPPPFAEHEFVKRHLPKLSKSSSMQPLTLLNSVEKEPSKFYSAHMQASVGCIS
GDLLPERYKSKRGRSKSKEMPHLEGPPKRTLKIPASKVFSVQSKEEQEPPVLHPEVEIPS
LRQSLAEQAFPKKRGRPKRQIRSGVKMAPPVLSMAPFVTADSSDKLESESDQQQSGDFLD
RPSQLEGPEELGKTSTCSMTDREGESDRKETKRNNGQLMKTIIRKINKMKTLKRKKLLNQ
ILSSTASEPNKGKVQSKFHTTVSTFAATFGSKLGQQINVSKKGTIYIGKRRGRKPKAVLN
GILAASPASLTVLEKSAQQAAGTGLGQAVPPLLPSATSNPEVLPSPVCSQSSGVSGGQSP
VSSDMGFVEPTSVPYLHLHSRPGSVLQTLAMRKASRARRRLSPPTLLPNSPSHMSELSSL
KEATPSPISESHSDETIPSDSGIGTDNNSTSDRAEKFCGPKKRRHSFDHVSLMPPETSTV
LSSLKEKHKHKCKRRSHDYLAYDKMKRQKRKRKKKYPQLRGRQDPGFLAELEELISRLSE
IRITHRSHHFIPRDLLPTIFRINFNSFYTHPTFPLDPLHYIRKPDLKKKRGRPPKMREAM
AEMPFMHSLSFPLSSTGFYPSYSMPYSPSPLAAAPIGLGYYGRYPPTLYPPPPSPSFTAP
LPPPSYMHTGHLLLNPAKYHKKKHKLLRQEAFLTASRAPLLSMSTYHPSVPPEMAYGWML
EHKHRHRHKHREHRSAEQPQVSIDPLAPSGPSRTVLESLKRYRFGKEAAGDRYKHKEKHR
CHMSYPHLSPSKGLLGREEQWVRREPAESSSLALGLQTPLQIDCSDAPPSLPLGKFTPSA
EPASGDEHTNLFTSAIGSCRVAGSASTGGRKKLSDGSGLFSPQEGSLGRPLRKETLPPVE
KTVAVLPGTLPAQDKLVQRSAEGTSCSPSRKRSSSESTSSTVVGIPARSTRLGNAMEDPV
DNLLQRMAQQENQGALDKTLETVMANTPTPPSGSPSRSPSREKSSGLLIPGDTDSTGLSL
LSERLSSSYSPHHLKRSMVEAMQCQARKMCNYDKLLATKKNLDHVNKILKAKKLQRQSRT
GNNFVKRRPGRPRKYPLPSVVSAHALHVSRFVGQDLDSRGRGCLLHCGPDTVTDAIESVV
QGVSVKGWKRKRWLEDEQARKKQKPLPEEEQESSKSFSEAAAETPPPAEAAAKPREPEST
EQPLPPVVLREKKAPRPPKKKYQKAGLYSDVYKTTDPKSRLIQLKKEKLEYTPGEHEYGL
LPAPIHVGKYLRQKRIDFQLPYDILWQWKHNQLYKKPDVPLYKKIRSNVYVDVKPLSGYE
ATTCNCKKPEDGSKTGCLDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRA
EEKGWGIRTKESLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSY
RMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQL
CKCGFDKCRGIIGGKSQRMNGLLSKTNQPVAAQRRPSRSKEKRKSKHKLKKRKGHVPEES
GESSSTPTRLTPQLQMKPMSNRERNFVLKHHVFLVRNWEKIRQKQEEVKHANDNLPSASL
YTRWNGMCRDDGNIKSDVFMTQFSALQTSRSVRTRRLAAAEENIEVARAARLAQIFKEIS
DGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEAFDG
DMLKVFRNAEKYYGRKSPIGRDVCRLRKAYYSARHEAAAQIDEIVGETASEADSSETSMC
EKESGHEKDEDVIRCICGLYKDEGLMIQCDKCMVWQHCDCMGLNADVEHYLCEQCDPRTV
DREVPMIPRPHYAQPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLLSH
INRERLDIFRIEKLWKNEKEERFAFGHHYFRPHETHHSPSRKFYHNELFRVPLYEIIPLE
AVVGTCCVLDLYTYCKGRPKGAKEQDVYICDYRLDKSAHLFYKIHRNRYPVCTKSYAFDH
FPKRLTPKRDFSPHYVPDNYKRNGGRSSWKSDRSKSQNKDLGQEEDPLPLMEDGVAGQER
PPGEQAPSLEEPEKGESGEVDKKAEESSPVARRPCTPEERRHMQRERLNQILLTLLEKIP
GKNAIDVTYLLEEGSGRKLRRRTLALVESSFRK
NT seq
9102 nt
NT seq
+upstream
nt +downstream
nt
atggaccctcagaatactgctatgttagggctgggttccggctctgaagggttttctggg
aaaagcccctctgcggttggcgcaggtgcgactggaggcaggagggaggcagaggtagat
ggtagcgcgaaggaggaggaagagaagaagaggagccgcgaggggagcgctggcgacgag
gctggcaaggatgagggcgcggcggatgcccagcagcagttttctgtgaaggagacaaac
ttttcggaggggaatttaaaactgaaaattggcctccaggctaagagaactaagaaaccc
cccaagaacctggaaaattatgtctgccggcctgccataaaaaccactatcaagcaaccc
aggaaggtgccgaaggtggggaagatgacggatgagaagagcgaccccagtcctccgcag
cctgatccatccaagctgtataaaaagggtggagaagctcccggattggttgagaattcc
acaagtgaaggcagaacgagggagagcagcccattttcgaagaaactttcgccactgcat
tctgaagtgacagaatatgcaaagtcagcactctccactccagtcagtagtcgcgatcca
gacccaaaggacagagctcagattaacggcacaccgacagtaacagaaaaactggctcat
cttattgcaacttgccctccatcaaagtcttccaaaacaaagcaaaagaagccacccact
ggaatcgcttccggatttgctaaagattctggaaagaagctggcaacagtcgggactgcg
accgcttccatttccaaggactttgtaaagaaacagcctggatgcagcagtatgggtgtt
gctttggtcaacaaggagtttgcaaagaaatcaccagggactagtaacagcactgggcta
attggcaaggactccgggagcaaaaaaccgccagggccatgtcctggtatggttgggcta
gttagtaaggattgtgggaagaagctaccagttctcacctctccagtgggactggtcagc
aaggaaagtgtcagaaggccacttgtgacgggcatgtcagttgggccagtgagcaaagag
tctgggaaaagactgctgggaactagtagtccaattggattggtgaacaaggattctggg
aaaaagctaggccttgtcagccctcctggactgattaacaaagagcctgggaaaaagttc
ccagtcccttgcagtccaattagattgtttaataaggatgctgggaagaaacagctgggg
gcagatgggcaaactggattgattagcaaggactctgggaagaaattaccagggtttggt
gcttcaagcggattggttaacaaagactctggaaagaagccattgggtgctaatagccca
atcgggttgattactaaagagtctgggaagaagccattgggggttggcattccagctact
ttgactgctaaggactctgggaagaagttggccggggccagcagtttgtgtgggctggct
aataaagatttgggaactctgaaggctgacgccgctagcccttcctcggagcccttcaag
cggtgttgtggcgcaagcctcacacgtctcgaaagtcctgcgcctccaggccttttgaag
gacaatgtcggcagtaaaccttttgagaaacatgttgcaagacagagcaaggagagcctt
cccgaaaagctgccggtgcagaaagacgccccaggaggagtcaaggatgggggctgcatt
cagcaggacagctctgctgccagtgaaaggggcgcttctgaagcacctaagcatgataaa
cagctgcctgtgtattgcacttcccccgacttcaggacatcgggaggcgcttccgatgta
tccacggccaaatctccatttagtgctgtaggggaggggggcctcccatctccctcccca
gctgcatcggtcaccactttaacccgtagccccacatcaaccttggctcagttagcctcc
aacccgctgcatttaaataacacgcctgagctcttagaaggaatttccgagcagattagc
aagaccccatttgcctctgatggcgcacgctcgagcatgagcaggccgttgaatcctggc
tcgcatgctcccggcaaaggggcaggcagggaagcgaaccattccggcgctgcgcacccg
gacgaccccaagccgaaccccgcggtgagcaaaaagccagtgctggtgccggaatccggc
atccgtccctccacggccccttcggtggtgagcttctccagcttgtttaacagcaagccc
ttcctcaagatcggttccatgacttcctctggaaagtcatgccaaggagtggactccctg
agcagcaccagtgggggctcccaagcgaagcccttgaagaagaggaaagggcggaagccg
cgctggacgaaggtggtctcgaggagcagctgccgaccttccaaaggcctagaattagga
aggcctgagcttttcagaaacctttcctgcagcacactgtccagcagttgcctggaccag
gccaagctctttaaaagcacagggccgcccccctttgcagagcatgaatttgtcaaacgc
catttgccaaagttgagtaagtccagcagcatgcagcctcttactctgctgaacagtgtt
gagaaggagcccagtaaattttacagtgcccacatgcaggcttccgtcgggtgcatttca
ggtgatttgttacctgaaaggtacaagtccaaaaggggcaggtcaaaatccaaagagatg
ccccacctggaaggccccccaaaacggaccctgaagatccctgcctccaaggtcttctcc
gtgcagtcgaaggaagagcaagagcctccagtgttgcatccggaagttgagattccctct
cttcggcagagccttgcggagcaagctttcccaaagaagaggggccggccaaaaagacaa
atccggtcaggggtcaagatggcacctcctgtcctctccatggcacctttcgtcactgcg
gacagctctgacaaactggagtctgagagcgaccagcagcagagtggggatttccttgac
cggccgagccagctagaaggccccgaggagcttgggaaaacaagtacctgcagcatgacc
gaccgggagggggaatcggaccgaaaggagaccaaacgcaacaatgggcagctcatgaaa
accatcatccgaaaaatcaacaagatgaagacattaaaaaggaagaagctcttgaatcag
atcctctcatcgactgcgtcagagccaaataaggggaaagtgcaatccaagttccacacc
acggtgtcgaccttcgccgccacgtttggttccaaactaggccagcagatcaatgtcagc
aagaaagggacgatctacataggaaagcggagaggccggaagccgaaagctgtcctgaat
ggtatcttggccgccagtcccgccagcttaactgttctcgaaaagtctgcccagcaggcc
gcagggacagggctcggacaagcagtacccccgttgcttccttcggccacaagtaaccct
gaagttcttccctcacctgtttgttcgcagtcttctggagtgagtggggggcaaagcccc
gtcagcagtgacatgggctttgtggaaccgacctcggtgccgtacctgcacctccactcc
aggccggggagtgtgcttcagaccctggctatgaggaaggcgtccagagccaggcggaga
ctctccccaccgacactcctccccaactccccgtcccacatgagcgagctcagctcgttg
aaggaagccaccccgtcgcccatcagcgaatcccacagcgacgagacgattcccagcgac
agtgggatcgggaccgacaacaacagcacttccgacagggcagaaaagttctgtggacca
aaaaagcgccggcactcgttcgaccacgtctccctcatgccccccgaaacctcgacggtc
ctgagcagcctcaaggaaaagcacaagcacaagtgcaagcgccggagccatgactacttg
gcctacgacaaaatgaagagacagaagcggaagaggaagaagaagtacccgcagctgcgg
ggcaggcaggaccccgggttcctggcagagctggaggagctgatcagtcgcctgagcgag
atccggatcacgcaccggagccaccacttcatcccccgggacttgctgcccaccattttc
cgcatcaatttcaacagcttctacacccaccccactttccctttggaccccttgcactac
atccggaagcctgacctgaagaagaagagaggccggcccccgaaaatgcgagaggcgatg
gcggaaatgcccttcatgcacagcctcagtttccccctctccagtactggattctacccc
tcctacagtatgccttactctccttcccccctggcggcagcccccattggcttgggctac
tacgggcggtaccccccgaccctctacccccctccgccgtccccttccttcaccgccccg
ctgccccctccctcctacatgcacaccggccacctgctcctcaacccggccaagtaccac
aagaagaaacacaagctgctgcgccaggaggccttcctcacggccagccgggcccccctc
ctctccatgagcacctaccaccccagcgtcccgcccgagatggcgtacggctggatgctc
gagcacaagcaccggcaccggcacaagcaccgggagcaccgctccgcggagcagccccag
gtttccatcgaccccctggcgcccagcggcccctcccggaccgtcctggagtccttgaag
cgctaccggtttgggaaggaggccgccggcgacaggtacaagcataaggagaagcaccgg
tgccatatgtcctaccctcacctgtccccttcgaaaggcctgctgggcagggaggagcag
tgggtccggagggagccggcggagtccagctcccttgccctgggattacagaccccgctg
cagatagactgctccgatgctcctcccagcctgcccttggggaagttcactccgagcgcc
gagccggccagcggtgacgaacacacaaaccttttcaccagtgcaataggcagctgccgg
gttgcgggctctgccagtaccggcgggcgtaaaaaactgtccgatggctcaggactcttc
agcccccaggaggggtctctaggccggcccctccgaaaggagacattgccccccgtggag
aagacggtggcagtcctgccagggacacttccagcgcaggacaaactcgtgcagaggtca
gcagagggcacaagctgcagcccttccagaaagaggtcttcatctgagagcacatcttct
acagtggttgggatcccggcacgaagtacaaggctggggaacgcgatggaagatcctgtg
gataatctgttgcagcgcatggcccagcaggaaaaccagggtgcgctggacaaaaccctt
gagactgtcatggcaaacacaccgactcctccttcggggagccccagtcggagtcccagc
agggagaagagcagcgggctcttgatcccaggtgacacggacagcaccggcctctcactc
ctttctgagcgcttgtccagcagctactcccctcatcacctcaagaggagcatggtggaa
gccatgcagtgccaggcgaggaaaatgtgcaattacgacaagctcttggccaccaagaag
aacctggaccacgtgaacaaaatcctcaaggccaagaagctgcagaggcagtcgcggacg
ggcaacaatttcgtgaagcgcaggccaggcaggccccggaagtacccgctgccctccgtc
gtctcggcccacgcgctccacgtgagccggtttgtcggccaggacctcgacagccggggc
cggggctgcctgctgcactgcgggccggacaccgtcacggacgccatcgaatcggtggtt
cagggagtgagcgtgaagggctggaaaaggaagcggtggctggaagacgagcaggccagg
aaaaagcagaagccgctcccggaggaagagcaggagagcagtaaaagcttttctgaggct
gcagcagagacccctcctcctgccgaggcggccgcaaagccacgcgagccggaaagcacg
gagcagccgctgccccccgtcgtgttacgcgagaagaaagctccccgcccaccaaagaag
aagtaccagaaggcagggctgtattctgacgtgtacaaaaccactgaccccaaaagccga
ctgatccagttaaagaaggaaaagctggaatacacccctggagagcatgagtacggcttg
ctcccggcccccattcatgtgggaaaatacctacgccaaaagcggatagacttccagttg
ccttatgacattctctggcagtggaaacataatcagttgtacaaaaagccagacgtccca
ctttacaaaaagatccgttcaaatgtttatgtggatgtgaaacctctttctggttatgag
gccacaacttgtaactgtaaaaaacctgaggacgggagcaaaactggatgtttagatgac
tgcttgaacaggatgatctttgccgagtgctcccccaacacctgcccctgcggggagcag
tgctgcaaccagaggatccagcggcacgagtgggtgcagtgcctggagcgcttccgggcc
gaggagaagggctggggcatccgcaccaaggagtccctgaaggccggccagttcatcatc
gagtacctgggagaagtggtcagcgagcaggagttccggaaccggatgattgagcagtac
cacaaccacagcgatcactactgcctcaacctcgacagcgggatggtgatcgacagctac
cgcatgggcaacgaggcccgtttcatcaaccacagctgcgaccccaactgcgagatgcag
aaatggtctgtcaacggggtctaccggattggcctgtacgcgctgaaggacatgccggcg
ggcaccgagctgacctatgactacaatttccactccttcaatgtggaaaagcagcaactc
tgcaaatgcggctttgacaagtgccgggggatcattgggggcaagagccagcgaatgaac
ggccttctgagcaaaaccaaccagccagtcgctgcgcagagaaggccgagccggtccaaa
gagaagaggaaatccaagcacaagttgaagaagaggaagggccacgttcccgaggagtcc
ggcgaaagctcgagcaccccgacccgtctgactccgcagctgcaaatgaagcccatgtcc
aacagggaacgaaattttgtgctcaagcatcacgtgttcctggtgcgcaactgggagaag
atccggcagaagcaagaggaggtcaaacatgccaacgacaaccttccttccgcctcctta
tacacccgctggaatgggatgtgccgcgacgacggcaacatcaaatctgatgtcttcatg
acacagttctccgccctgcagacctcccgctcggtgcgaacgcggcggttggcggcagcc
gaagagaacatcgaagtggcgcgtgcagcccggctggcacaaatcttcaaggagatctcc
gatggcatcatctcatacaaagattcctccaggcaagcactcgcggctccgttgctgaat
cttcccccaaagaaaaaaaatgccgactactacgagaagatctctgacccccttgacctc
atcaccatcgagaagcaaatcctgacggggtattacaaaacggtggaagcgttcgatggc
gacatgctgaaggtcttccgcaacgccgagaaatactacggcaggaagtctcccatcgga
cgggacgtctgccggctgcggaaggcgtactacagcgcccgccacgaggccgccgcccag
atcgacgagatcgtgggggagacggcgagcgaggccgacagcagcgagacctccatgtgc
gagaaggagagcgggcacgagaaggacgaggacgtgatccgctgcatctgcggcctgtac
aaggacgaggggctcatgatccagtgcgacaagtgcatggtttggcagcactgtgactgc
atggggctgaacgccgacgtcgagcactacttgtgcgagcagtgtgaccctcgcacggtg
gacagggaggtgccgatgatcccccggcctcactacgcccagcccggctgcgtttatttc
atctgcctgttacgggacgatctgttactgcgccaaggggactgcgtgtacctgatgaga
gacagccgaaggaccccagatggccaccccgtccggcagtcgtaccgcctgctgtcccac
atcaaccgagagagactcgacatcttccgcatcgagaagctctggaagaacgagaaggag
gagcgcttcgccttcggccaccactacttccgtccgcacgaaacacaccactccccctcc
cggaagttctaccacaacgaactcttccgggtgcccctgtacgagatcatccccctggag
gccgtggtgggcacctgctgcgtgctggacctctacacctactgcaaaggaaggccaaag
ggggcgaaggaacaggacgtgtacatctgtgattaccgcctcgacaaatcagcccacctc
ttctacaagatccaccgaaatcggtatccggtgtgcaccaagtcctacgccttcgaccac
ttccccaaaaggttgacaccgaagagggacttctcgcctcattatgtaccggacaactat
aagaggaatggaggcaggtcgtcgtggaagtccgaccgttccaagtcccagaacaaagac
ctcggccaggaggaggacccgcttcccctcatggaggacggcgtggcggggcaggagcgg
ccccccggtgagcaggcgcccagcttggaggagcccgagaagggggaaagcggcgaggtg
gacaagaaggcggaggagagcagccccgtcgcgaggcggccctgcacccctgaggaacgc
cggcacatgcagcgcgagcggctcaaccaaatcctcctgaccctcctagagaaaatccca
gggaaaaatgccatcgatgtcacctacctgctggaggaaggctcggggaggaagctgcgg
cggcgcactctggcccttgtggagagcagcttccggaagtga
DBGET
integrated database retrieval system
