Vulpes lagopus (Arctic fox): 121490144
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Entry
121490144 CDS
T07435
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
vlg
Vulpes lagopus (Arctic fox)
Pathway
vlg00230
Purine metabolism
vlg01100
Metabolic pathways
vlg04927
Cortisol synthesis and secretion
vlg04934
Cushing syndrome
vlg05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
vlg00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
121490144 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
121490144 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
121490144 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
121490144 (PDE8A)
Enzymes [BR:
vlg01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
121490144 (PDE8A)
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GFIT
Motif
Pfam:
PDEase_I
PAS
PAS_9
PDE8
PAS_4
PAS_3
PAS_8
DUF5894
Sina_ZnF
Response_reg
Motif
Other DBs
NCBI-GeneID:
121490144
NCBI-ProteinID:
XP_041609762
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Position
4:114404862..114559372
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AA seq
838 aa
AA seq
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MGCAPSIHISEGRAVYHGGKEAEDAPAAAAPPPPPPPPAGPKTTASPRARGAGLAEPEPR
DGSGRKVAVTDVQFGPMRFHPDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTKEAQAV
LACFLDKHHDIVIIDHRNPRQLDAEALCRSIRSSELSENTIIIGVVRRTDREESSVMPLI
AAGFTRRYVENPSLMACYNELLQLEFGEVRSQLKLRACNSIFTALEKSQEAIEITSEDRV
IQYANPAFETTMGYQSGELIGKELAEVPINEKKADLLDTINSCIRIGKEWQGIYHAKKKN
GDNVQQNVKIIPVIGQGGKIRHYVSIIRVCNGSNKAEKITECVQSDTHTDNQSGKHKDRR
KSSLDVRTLASRTSEVGSQRRHSSMARIHSMTIEAPITKVINIINAAQESSPMPVTEALD
RVLEILRSTELYSPQFGAKDDDPHANDLVGGLMSDGLRRLSGNEYVLSTKNLQQVPSSII
TPISLHDVPPRIARAMENEEYWDFNIFELEAATNKRPLIYLGLKIFARFGICEFLNCSET
TLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLCKERIKISCLQQTLDPVDEVAALI
AATIHDVDHPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTRDDKCNIFKNMER
NDYRTLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLAALEVNGEVNRDEEAINTMLRSP
ENRTLIKRMLIKCADVSNPCRPLEQCIEWAARISEEYFSQTDEEKRQDLPVVMPVFDRNT
CSIPKSQISFIDYFITDMFDAWDAFVDLPELMQHLDNNFKYWKGLDEMKLRSLRPPPE
NT seq
2517 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgccccgagcatccacatttccgagggccgggcggtgtaccacggcggcaag
gaggccgaggacgcgccggccgccgccgcgccgccgccgccgccgccgccgcccgccggc
ccgaagaccaccgcctcgccccgggcccgcggcgccggcctcgcggagcccgagcctcgc
gacggcagcggcaggaaggtagcagtaactgatgtgcagtttggccccatgagatttcat
ccagatcaactccaggtacttttagtgtttaccaaagaagataaccagtgtaatggattc
tgcagggcatgcgaaaaagcagggtttaagtgcacagttaccaaggaggctcaggctgtc
cttgcctgtttcctggacaaacatcacgacattgtcatcattgaccacagaaacccccgg
cagctggacgcagaggcgctatgcaggtctatcagatcctcagaactctctgaaaacaca
attattattggtgtagtacggaggacggatagagaagagtcctctgtgatgcccctcatt
gctgctggctttacaaggaggtatgtggaaaaccccagcctcatggcctgttacaatgaa
ctgctccagctggagttcggagaggtgcggtcccagctgaaactcagggcttgtaactca
atattcacggcattagagaaaagtcaagaagcaattgaaattacaagtgaagaccgcgtt
atacagtatgcaaatcctgcatttgaaacaaccatgggctatcagtcaggtgaattaata
ggaaaggagttagcagaagtgcctataaatgaaaaaaaggctgatttgctcgatactata
aattcatgcatcaggataggcaaggagtggcaaggaatctaccatgccaaaaagaaaaat
ggagataatgtgcaacaaaatgtgaagataatacctgtcattggacagggaggaaaaatt
agacactatgtgtccattatcagagtgtgcaatggcagtaataaggctgagaaaataact
gaatgtgttcagtctgacactcatacagataatcagtcaggcaaacataaagacagaagg
aaaagctcgctagatgtcagaactcttgcttctcgaacaagtgaagttggcagtcagaga
cgacactcctccatggcccggatacattccatgacgattgaggcgcccatcaccaaggta
atcaacattatcaacgctgcccaggagagcagccccatgcctgtgacggaagccttagac
cgtgtgctggaaatcctgagaagcactgaattatattcaccacagtttggtgctaaggat
gatgatcctcatgccaatgaccttgttgggggcttaatgtctgatggtttgcgaagactc
tctgggaatgagtatgttctttcgacaaaaaatcttcagcaggtgcccagcagtataatc
acccccatctcccttcatgatgtccccccacggatagctcgggccatggaaaacgaggag
tactgggacttcaatatttttgaactggaggctgccacaaataaaaggcctttgatttat
cttggtctcaaaatatttgctcgcttcggaatctgtgaattcttgaactgctccgagaca
acactgagatcatggttacagattattgaagccaattaccactcttctaacccctaccac
aactccacacactctgctgacgtgcttcacgccactgcctactttctctgcaaagagaga
ataaagatctcttgtttgcagcaaactttagatccagttgatgaggtcgctgccctcatc
gcagccaccatccacgacgtggaccaccctgggagaaccaactccttcctgtgcaatgct
ggaagcgagctggccattttgtataatgacactgctgtgctggagagccaccatgcggct
ctggccttccagctgaccacccgggatgacaaatgcaatatcttcaaaaacatggagagg
aatgactatcggacgctgcgccagggtatcatcgacatggtcttagccacagaaatgaca
aagcacttcgagcatgtcaacaaatttgtcaacagcatcaacaagcccctggcagccctc
gaagtaaatggggaagtgaatagagacgaagaagccataaacactatgcttagaagtcca
gagaaccggactctgattaaacggatgctgattaaatgtgcggatgtgtccaatccctgc
cgacccctagagcagtgcattgagtgggccgcacgcatctcagaagaatatttttctcag
actgatgaggagaagcggcaggacttacctgtggtgatgccagtttttgacagaaacacc
tgcagcatccccaaatcccagatctccttcatcgactacttcatcaccgacatgttcgat
gcttgggacgcctttgtagacctgcctgagttaatgcagcatcttgacaacaactttaaa
tactggaaaggactggatgagatgaagctgcggagcctccgaccgccccccgaatag
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