Vulpes vulpes (red fox): 112921341
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Entry
112921341 CDS
T05911
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
vvp
Vulpes vulpes (red fox)
Pathway
vvp00230
Purine metabolism
vvp01100
Metabolic pathways
vvp04927
Cortisol synthesis and secretion
vvp04934
Cushing syndrome
vvp05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
vvp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
112921341 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
112921341 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
112921341 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
112921341 (PDE8A)
Enzymes [BR:
vvp01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
112921341 (PDE8A)
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Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PAS
PAS_9
PAS_4
PAS_3
PAS_8
DUF5894
Sina_ZnF
Response_reg
Motif
Other DBs
NCBI-GeneID:
112921341
NCBI-ProteinID:
XP_025856320
UniProt:
A0A3Q7TMH3
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All DBs
Position
Unknown
AA seq
757 aa
AA seq
DB search
MRFHPDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTKEAQAVLACFLDKHHDIVIIDH
RNPRQLDAEALCRSIRSSELSENTIIIGVVRRTDREESSVMPLIAAGFTRRYVENPSLMA
CYNELLQLEFGEVRSQLKLRACNSIFTALEKSQEAIEITSEDRVIQYANPAFETTMGYQS
GELIGKELAEVPINEKKADLLDTINSCIRIGKEWQGIYHAKKKNGDNVQQNVKIIPVIGQ
GGKIRHYVSIIRVCNGSNKAEKITECVQSDTHTDNQSGKHKDRRKSSLDVRTLASRTSEV
GSQRRHSSMARIHSMTIEAPITKVINIINAAQESSPMPVTEALDRVLEILRSTELYSPQF
GAKDDDPHANDLVGGLMSDGLRRLSGNEYVLSTKNLQQVPSSIITPISLHDVPPRIARAM
ENEEYWDFNIFELEAATNKRPLIYLGLKIFARFGICEFLNCSETTLRSWLQIIEANYHSS
NPYHNSTHSADVLHATAYFLCKERIKQTLDPVDEVAALIAATIHDVDHPGRTNSFLCNAG
SELAILYNDTAVLESHHAALAFQLTTRDDKCNIFKNMERNDYRTLRQGIIDMVLATEMTK
HFEHVNKFVNSINKPLAALEVNGEVNRDEEAINTMLRSPENRTLIKRMLIKCADVSNPCR
PLEQCIEWAARISEEYFSQTDEEKRQDLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDA
WDAFVDLPELMQHLDNNFKYWKGLDEMKLRSLRPPPE
NT seq
2274 nt
NT seq
+upstream
nt +downstream
nt
atgagatttcatccagatcaactccaggtacttttagtgtttaccaaagaagataaccag
tgtaatggattctgcagggcatgcgaaaaagcagggtttaagtgcacagttaccaaggag
gctcaggctgtccttgcctgtttcctggacaaacatcacgacattgtcatcattgaccac
agaaacccccggcagctggacgcagaggcgctatgcaggtctatcagatcctcagaactc
tctgaaaacacaattattattggtgtagtacggaggacggatagagaagagtcctctgtg
atgcccctcattgctgctggctttacaaggaggtatgtggaaaaccccagcctcatggcc
tgttacaatgaactgctccagctggagttcggagaggtgcggtcccagctgaaactcagg
gcttgtaactcaatattcacggcattagagaaaagtcaagaagcaattgaaattacaagt
gaagaccgcgttatacagtatgcaaatcctgcatttgaaacaaccatgggctatcagtca
ggtgaattaataggaaaggagttagcagaagtgcctataaatgaaaaaaaggctgatttg
ctcgatactataaattcatgcatcaggataggcaaggagtggcaaggaatctaccatgcc
aaaaagaaaaatggagataatgtgcaacaaaatgtgaagataatacctgtcattggacag
ggaggaaaaattagacactatgtgtccattatcagagtgtgcaatggcagtaataaggct
gagaaaataactgaatgtgttcagtctgacactcatacagataatcagtcaggcaaacat
aaagacagaaggaaaagctcgctagatgtcagaactcttgcttctcgaacaagtgaagtt
ggcagtcagagacgacactcctccatggcccggatacattccatgacgattgaggcgccc
atcaccaaggtaatcaacattatcaacgctgcccaggagagcagccccatgcctgtgacg
gaagccttagaccgtgtgctggaaatcctgagaagcactgaattatattcaccacagttt
ggtgctaaggatgatgatcctcatgccaatgaccttgttgggggcttaatgtctgatggt
ttgcgaagactctctgggaatgagtatgttctttcgacaaaaaatcttcagcaggtgccc
agcagtataatcacccccatctcccttcatgatgtccccccacggatagctcgggccatg
gaaaacgaggagtactgggacttcaatatttttgaactggaggctgccacaaataaaagg
cctttgatttatcttggtctcaaaatatttgctcgcttcggaatctgtgaattcttgaac
tgctccgagacaacactgagatcgtggttacagattattgaagccaattaccactcttct
aacccctaccacaactccacacactctgctgacgtgcttcacgccactgcctactttctc
tgcaaagagaggataaagcaaactttagatccagttgatgaggtcgctgccctcatcgca
gccaccatccacgacgtggaccaccctgggagaaccaactccttcctgtgcaatgctgga
agcgagctggccattttgtataatgacactgctgtgctggagagccaccatgcggctctg
gccttccagctgaccacccgggatgacaaatgcaatatcttcaaaaacatggagaggaat
gactatcggacgctgcgccagggtatcatcgacatggtcttagccacagaaatgacaaag
cacttcgagcatgtcaacaaatttgtcaacagcatcaacaagcccctggcagccctcgaa
gtaaatggggaagtgaatagagatgaagaagccataaacactatgcttagaagtccagag
aaccggactctgattaaacggatgctgattaaatgtgcggatgtgtccaatccctgccga
cccctagagcagtgcattgagtgggccgcacgcatctcagaagaatacttttctcagact
gatgaggagaagcggcaggacttacctgtggtgatgccagtttttgacagaaacacctgc
agcatccccaaatcccagatctccttcatcgactacttcatcaccgacatgttcgatgct
tgggacgcctttgtagacctgcctgagttaatgcagcatcttgacaacaactttaaatac
tggaaaggactggatgagatgaagctgcggagcctccgaccgccccccgaatag
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