Xenopus laevis (African clawed frog): 447204
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Entry
447204 CDS
T01010
Symbol
hmgcs1.S, hmgcs1
Name
(RefSeq) 3-hydroxy-3-methylglutaryl-CoA synthase 1 S homeolog
KO
K01641
hydroxymethylglutaryl-CoA synthase [EC:
2.3.3.10
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla00280
Valine, leucine and isoleucine degradation
xla00650
Butanoate metabolism
xla00900
Terpenoid backbone biosynthesis
xla01100
Metabolic pathways
xla03320
PPAR signaling pathway
Module
xla_M00095
C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
447204 (hmgcs1.S)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
447204 (hmgcs1.S)
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
447204 (hmgcs1.S)
09150 Organismal Systems
09152 Endocrine system
03320 PPAR signaling pathway
447204 (hmgcs1.S)
Enzymes [BR:
xla01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.10 hydroxymethylglutaryl-CoA synthase
447204 (hmgcs1.S)
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GFIT
Motif
Pfam:
HMG_CoA_synt_C
HMG_CoA_synt_N
ACP_syn_III
Motif
Other DBs
NCBI-GeneID:
447204
NCBI-ProteinID:
NP_001087380
Xenbase:
XB-GENE-6077850
UniProt:
Q6AX99
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Position
1S:183706569..183727903
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AA seq
520 aa
AA seq
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MPGSLPPNGESSWPKDVGIVALEIYFPSQYVDQEELEKFDGVSAGKYTIGLGQSKMGFCS
DREDINSLCLTAVQRLMERNNLSYDCIGRLEVGTETIIDKSKSVKTVLMQLFEESGNTDV
EGIDTTNACYGGTAALFNAVNWVESSSWDGRYALVVAGDIAVYATGSARPTGGAGAVAML
VGPNATLVFERGLRGTHMQHAYDFYKPDMESEYPVVDGKLSIQCYLSALDHCYSTYRKKI
HAQWQKEGTEKPFTLNDFGFMIFHSPYCKLVQKSFARLLVNDFISDSNPNTESGVYVGLD
SFRDLKLEETYFDRDVEKAFLKASTELFNEKTKTSLLVSKENGNMYTPSVYGCLASVLAQ
YSPQQLAGQRIGVFSYGSGFAATLYSLRVSQDAMPGSSLDKLTSSLSDLKARLDSRKNVS
PSIFADNMKLREDTHHLANYVPQGSVDDLFPGTWYLVRVDEKHRRFYARSSLMRDGPLDA
APESVHSSTANEHFPSPAKKVPRIPPAAEAEPISVTNGGH
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atgcctggatcccttcctccaaacggtgaaagctcttggcccaaagacgtgggtattgtt
gccctagagatttacttcccgtcccagtatgtcgatcaagaagagctggagaaattcgat
ggggtcagtgctggaaaatacaccatcggcttgggacagtccaagatgggcttctgctcg
gacagagaagacatcaattctctgtgtctcacagcggtgcaaagactaatggagaggaac
aatctgtcttacgactgcataggccgactggaggtgggaacagagacaatcattgacaag
tccaaatctgtaaagactgtcctgatgcagctgtttgaggaatcggggaacaccgatgtg
gaaggcatcgatacaacaaacgcatgttatggaggcacggccgctctcttcaatgccgtc
aactgggtggaatcaagttcttgggatggacgctacgcgcttgtggttgctggagacatc
gctgtgtatgccacgggaagtgccaggccaaccggaggagccggagccgttgccatgctc
gtggggccaaatgctactttggtttttgaaagaggtctgcgtggaacacacatgcaacat
gcctatgatttttataagccagatatggaatcggaataccccgttgttgatggaaagctt
tcaatacagtgttacctcagcgcattagaccactgctactctacttaccgcaagaaaatc
catgcccagtggcagaaagagggaactgagaaacccttcactttgaatgactttggattc
atgatctttcattcgccgtactgcaaacttgtccagaaatccttcgctcggttgctggtg
aatgacttcatcagtgattccaacccaaatactgagagtggagtgtacgttggcctggat
tcatttagagatttaaagctggaagagacttattttgacagagatgtagaaaaggcattc
ctgaaggccagcacagaacttttcaatgaaaagactaaaacatctctgctggtgtctaag
gaaaatgggaatatgtacacaccgtctgtgtatggatgccttgcctctgtgcttgcacag
tattcgcctcagcagttggctggacaaaggataggtgtgttctcctatggctcaggcttt
gctgccactttgtattctctgagagtttcacaggacgctatgccaggttcttccttggac
aagttgacttccagcttgtcggaccttaaagcaagacttgactccagaaaaaacgtttca
cccagcatctttgctgacaacatgaagctccgggaagacacacatcatttagctaattat
gttcctcaggggtcggtggatgatctgtttccaggtacatggtatctggtccgtgttgat
gagaagcacaggaggttctatgcccgcagttcactcatgagagatggacctttagatgct
gcacctgaatctgttcactcaagcaccgctaatgagcatttcccaagccctgctaagaaa
gtccccagaatccctccggcagcagaagccgagcccatctctgttaccaacggggggcac
tga
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