Yersinia enterocolitica (type O 5) YE53/03: YE5303_42351
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Entry
YE5303_42351 CDS
T03739
Symbol
metL
Name
(GenBank) bifunctional aspartokinase/homoserine dehydrogenase II
KO
K12525
bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:
2.7.2.4
1.1.1.3
]
Organism
yee
Yersinia enterocolitica (type O:5) YE53/03
Pathway
yee00260
Glycine, serine and threonine metabolism
yee00261
Monobactam biosynthesis
yee00270
Cysteine and methionine metabolism
yee00300
Lysine biosynthesis
yee01100
Metabolic pathways
yee01110
Biosynthesis of secondary metabolites
yee01120
Microbial metabolism in diverse environments
yee01230
Biosynthesis of amino acids
Module
yee_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
yee_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
yee_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
yee00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
YE5303_42351 (metL)
00270 Cysteine and methionine metabolism
YE5303_42351 (metL)
00300 Lysine biosynthesis
YE5303_42351 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
YE5303_42351 (metL)
Enzymes [BR:
yee01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
YE5303_42351 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
YE5303_42351 (metL)
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
Motif
Other DBs
NCBI-ProteinID:
CCQ38526
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Position
130653..133088
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AA seq
811 aa
AA seq
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MNATAVAAAVTGRQLHKFGGSSLADVKCYLRVANIMANYSHPGDLMVVSAAGSTTNQLIS
WLKLSQTDRLSAHQVQQNLRRYQHDLISGLLSPEMAEPLISEFIHDLERLAGLLDNKVDD
AIYAEVVGHGEIWSARLMSAVLNKLDMDADWLDARSFLRAERAAQPQIDEGRSYPLLQQL
MAQHPHQRLVVTGFISRNNAGETVLLGRNGSDYSATQVGALAGVERVTIWSDVAGVYSAD
PRKVKDACLLPLLRLDEASELARLAAPVLHTRTLQPVSGSDIDLQLRCSYQPEQGSTRIE
RVLASGSGAKIVTSHDDVCLIELQIAGHHDFSLAQKEIDLLLKRAQIKPLATGIHPDRNL
LQLCYTSEVVNSALRVLEDATLPGKLSLREGLALVALVGAGVSKNPLHSHRFYQQLKDQP
VEFIWQAEDGISMVAVLRLGPTEHLIQGLHQSLFRAEKRIGLMLFGKGNIGARWLELFAR
EQKNISARSGFEFVLAGVVDSRRSLLSYDGLDASRTLAFYDDEAKEQDEESLFLWMRAHP
FDDLVVLDVTASESLAEQYLDFASYGFHVISANKLAGASSSNNYRQIRDAFAKTGRHWLY
NATVGAGLPVNHTVRDLRDSGDSILAISGIFSGTLSWLFLQFDGTVPFTELVDQAWQQGL
TEPDPRVDLSGQDVMRKLVILAREAGYDIEPNQVRVESLVPAGADVGSVDQFFENGEALN
QQMIQRLEAANEMGLVLRYVARFDANGKARVGVEAVRADHPLASLLPCDNVFAIESRWYR
DNPLVIRGPGAGRDVTAGAIQSDLNRLSQLL
NT seq
2436 nt
NT seq
+upstream
nt +downstream
nt
atgaatgcaacagcggtagcagcggcggtgaccggccgtcaactgcataaatttggtggt
agtagtcttgcggatgtgaagtgttacctgcgggtggccaatattatggccaactacagt
catcccggcgatcttatggtggtgtctgcggcaggtagcaccacaaaccagctgattagc
tggttgaagctgagtcaaactgatcgcctttctgctcatcaggtgcagcaaaacctgcgt
cgttaccaacatgacttgattagtggtttattgtcgccagaaatggccgagccgttaatt
agtgaatttattcatgatttggaacgcctggctggcctgttggacaacaaagtcgacgat
gcaatctatgccgaagtggttggtcatggtgagatttggtcggcccgcttgatgtctgcg
gtgttgaacaaactcgatatggatgccgactggctcgatgctcgcagtttcctgcgtgct
gaacgtgcggcacagccacaaatcgacgaaggccgttcatatccgttgttgcagcaatta
atggcacaacacccacaccaacgtctggtggtgacggggtttatttcgcgcaataacgcc
ggtgaaaccgtgttgttggggcgtaacggcagtgactactcggccactcaggttggggca
ctggcaggggtcgaacgtgtcaccatctggagtgatgtggcgggggtatacagtgctgac
ccgcgcaaagtgaaagatgcttgtttgttacctttactgcggctggatgaagccagtgaa
ctggctcggttggcagctccggtactgcatacccgtaccctacagccggtttccggcagc
gatattgatttacaactgcgttgtagctatcagccagaacagggctcaacccgtattgag
cgggtgctggcttccgggtcaggtgccaaaattgtcaccagtcacgatgatgtctgcctg
atcgaattacagattgccggccaccatgatttctcgctggcacagaaagagatcgattta
ctgctcaaacgcgcgcaaatcaagccgctggctaccggtattcatcctgatcgtaatcta
ttgcaactttgctatacctccgaagtggttaacagcgcattaagagtgctggaggatgcc
acgctgccagggaaattatctctgcgcgaggggttggctctggtcgctttggtcggcgct
ggggtcagcaagaacccattgcatagccaccgtttctatcaacaactgaaagatcagccc
gtcgagtttatttggcaggcggaagatggcatcagtatggttgcggtgctgcgtctcggg
ccgactgagcacttgattcagggcttacaccaatcactgttccgtgcagagaagcgcatc
ggtttgatgctgtttggtaaaggcaatattggtgctcgctggttggagctatttgcccgt
gagcagaagaatatctcagctcgcagtggttttgagttcgtgctagccggtgtggtagat
agccgccgtagtttgttaagttatgacgggctggacgctagccggacgctggcattttac
gatgatgaagctaaagagcaggatgaagaatccttgttcttgtggatgcgcgcgcaccca
tttgatgatttggtggtgttggatgtgaccgccagtgagtcacttgctgagcagtatctg
gatttcgccagctatggtttccacgttatcagcgccaataaattagccggagcctccagc
agcaataattaccgccaaatccgtgatgcttttgctaaaactggccgccactggttgtat
aacgccacggtgggcgcggggttaccggtcaaccataccgtgcgcgatttgcgcgatagc
ggcgacagtattctggcgatcagcggtattttctctggcactctgtcctggctgttcttg
caatttgacggcacggtgccctttaccgagctggtggatcaagcctggcaacagggcttg
accgaaccggatccgcgtgtcgatctctccgggcaagacgtgatgcgcaagctggtgatt
ttagctcgtgaagccggttacgacattgaaccgaatcaggtgcgggtggagtcgctagtc
cctgcgggtgccgatgttggttccgtagatcaattttttgagaatggcgaagcattgaat
cagcaaatgattcagcgcttagaagcagccaatgaaatgggtctggtgctccggtacgtc
gcgcgctttgatgccaatggtaaggcgcgagtgggcgttgaagcagtacgtgctgatcat
ccgttagcttcgttgctgccatgcgataacgtttttgccatcgagagccgttggtatcgc
gataacccgttggttattcgtggcccaggggcagggcgcgatgttactgccggtgctatt
cagtctgatttaaaccgcctgtcccagctgttgtaa
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