+F Repair protein KO
#
DNA Repair and Recombination Proteins - Ascochyta rabiei
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D EKO05_0004162 Methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D EKO05_0004572 Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D EKO05_0002622 Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E EKO05_0009513 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E EKO05_0003814 Thymine-DNA glycosylase K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E EKO05_0000870 uncharacterized protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E EKO05_0002034 DNA-(apurinic or apyrimidinic site) lyase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E EKO05_0007632 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E EKO05_0000847 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E EKO05_0000361 DNA-(apurinic or apyrimidinic site) lyase K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E EKO05_0004458 DNA-(apurinic or apyrimidinic site) lyase K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F EKO05_0007659 DNA-directed DNA polymerase K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F EKO05_0008031 DNA polymerase delta small subunit Cdc1 K02328 POLD2; DNA polymerase delta subunit 2
F EKO05_0009277 uncharacterized protein K03505 POLD4; DNA polymerase delta subunit 4
E DNA polymerase epsilon complex
F EKO05_0009539 DNA-directed DNA polymerase K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F EKO05_0000523 DNA-directed DNA polymerase K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
E EKO05_0001863 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E EKO05_0000132 Elongation of fatty acids protein 2 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E EKO05_0001761 uncharacterized protein K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
D Other BER factors
E EKO05_0011124 uncharacterized protein K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E EKO05_0005527 uncharacterized protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E EKO05_0007112 NAD(+) ADP-ribosyltransferase K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F EKO05_0005603 uncharacterized protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F EKO05_0010891 uncharacterized protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F EKO05_0008632 UV excision repair protein rad23 K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F EKO05_0003090 Cullin-RING-type E3 NEDD8 transferase K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F EKO05_0005276 uncharacterized protein K10609 CUL4; cullin 4
F EKO05_0009133 uncharacterized protein K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
F EKO05_0006454 UV-damaged DNA-binding protein rad7 K15082 RAD7; DNA repair protein RAD7
F EKO05_0002825 DNA repair protein rad16 K15083 RAD16; DNA repair protein RAD16
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F EKO05_0003707 DNA-directed RNA polymerase II subunit RPB1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F EKO05_0003642 DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F EKO05_0006219 RNA polymerase II subunit 3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F EKO05_0001900 RNA polymerase B K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F EKO05_0000313 DNA-directed RNA polymerases II 24 kDa polypeptide (RNA polymerase II subunit 5) K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F EKO05_0004189 subunit common to RNA polymerases I, II, and III K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F EKO05_0002350 DNA-directed RNA polymerase II subunit K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F EKO05_0009037 DNA-directed RNA polymerases I, II, and III subunit RPABC3 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F EKO05_0011223 uncharacterized protein K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F EKO05_0004873 DNA-directed RNA Polymerase II subunit L, variant 2 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
E Cul4-CSA complex
F EKO05_0003090 Cullin-RING-type E3 NEDD8 transferase K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F EKO05_0005276 uncharacterized protein K10609 CUL4; cullin 4
F EKO05_0009133 uncharacterized protein K10610 DDB1; DNA damage-binding protein 1
F EKO05_0008445 uncharacterized protein K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F EKO05_0004854 DNA repair protein rhp26 K10841 ERCC6; DNA excision repair protein ERCC-6
F EKO05_0003123 uncharacterized protein K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E EKO05_0009932 DNA helicase K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E EKO05_0001015 DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E EKO05_0005968 RNA polymerase II transcription factor B subunit 1 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E EKO05_0008762 uncharacterized protein K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E EKO05_0001731 RNA polymerase II transcription factor B subunit 4 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E EKO05_0004817 RNA polymerase II transcription factor B 52 kDa subunit K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E EKO05_0005685 uncharacterized protein K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E EKO05_0008207 [Pyruvate dehydrogenase (acetyl-transferring)] kinase K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E EKO05_0002984 uncharacterized protein K06634 CCNH; cyclin H
E EKO05_0010845 TFIIH/NER complex subunit K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E EKO05_0000568 Replication factor A protein 1 K07466 RFA1; replication factor A1
E EKO05_0001517 Replication factor A protein 2 K10739 RFA2; replication factor A2
E EKO05_0007608 uncharacterized protein K10740 RPA3; replication factor A3
D Other NER factors
E EKO05_0003055 DNA repair protein rad14 K10847 XPA; DNA-repair protein complementing XP-A cells
E EKO05_0001698 ssDNA endonuclease and repair protein rad10 K10849 ERCC1; DNA excision repair protein ERCC-1
E EKO05_0006645 DNA repair protein RAD16 K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E EKO05_0004123 DNA repair protein rad2 K10846 ERCC5; DNA excision repair protein ERCC-5
E EKO05_0001761 uncharacterized protein K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E EKO05_0001909 uncharacterized protein K15075 MET18; DNA repair/transcription protein MET18/MMS19
E EKO05_0000245 uncharacterized protein K03869 CUL3; cullin 3
E EKO05_0001653 elongin C K03872 ELOC; elongin-C
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E EKO05_0001193 MSH2 protein K08735 MSH2; DNA mismatch repair protein MSH2
E EKO05_0008140 Mismatch repair protein msh3 K08736 MSH3; DNA mismatch repair protein MSH3
E EKO05_0004243 DNA mismatch repair protein msh6 K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E EKO05_0009207 DNA mismatch repair protein Mlh1 K08734 MLH1; DNA mismatch repair protein MLH1
E EKO05_0000969 ATP-binding mismatch repair protein K10858 PMS2; DNA mismatch repair protein PMS2
E EKO05_0007525 DNA mismatch repair protein K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E EKO05_0007659 DNA-directed DNA polymerase K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E EKO05_0008031 DNA polymerase delta small subunit Cdc1 K02328 POLD2; DNA polymerase delta subunit 2
E EKO05_0009277 uncharacterized protein K03505 POLD4; DNA polymerase delta subunit 4
D RPA (replication factor A)
E EKO05_0000568 Replication factor A protein 1 K07466 RFA1; replication factor A1
E EKO05_0001517 Replication factor A protein 2 K10739 RFA2; replication factor A2
E EKO05_0007608 uncharacterized protein K10740 RPA3; replication factor A3
D RFC (replication factor C)
E EKO05_0006182 DNA replication factor C complex subunit Rfc1 K10754 RFC1; replication factor C subunit 1
E EKO05_0008604 replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
E EKO05_0001940 Subunit of heteropentameric Replication factor C (RF-C) K10755 RFC2_4; replication factor C subunit 2/4
E EKO05_0002854 Subunit of heteropentameric Replication factor C (RF-C) K10756 RFC3_5; replication factor C subunit 3/5
E EKO05_0006307 Replication factor C (RF-C) subunit K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E EKO05_0001863 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E EKO05_0009826 Rad2 nuclease K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E EKO05_0001761 uncharacterized protein K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E EKO05_0000621 uncharacterized protein K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E EKO05_0001401 meiotic recombination K10865 MRE11; double-strand break repair protein MRE11
E EKO05_0003639 DNA repair protein rad50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
E EKO05_0001401 meiotic recombination K10865 MRE11; double-strand break repair protein MRE11
E EKO05_0003639 DNA repair protein rad50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA complex
E EKO05_0001365 RecA recombinase Rhp51 K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E EKO05_0001365 RecA recombinase Rhp51 K04482 RAD51; DNA repair protein RAD51
E EKO05_0008769 DNA repair protein rhp57 K10958 RAD57; DNA repair protein RAD57
D Rad52 family proteins
E EKO05_0007374 DNA repair protein rad52 K10873 RAD52; DNA repair and recombination protein RAD52
D Rad54 family proteins
E EKO05_0000487 DNA-dependent ATPase protein rad54 K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E EKO05_0006855 helicase K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E EKO05_0004590 uncharacterized protein K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E EKO05_0005191 uncharacterized protein K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E EKO05_0005195 uncharacterized protein K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E EKO05_0006137 uncharacterized protein K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E EKO05_0007599 uncharacterized protein K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E EKO05_0008463 uncharacterized protein K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E EKO05_0008902 uncharacterized protein K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E EKO05_0009406 uncharacterized protein K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E EKO05_0009852 DNA helicase K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E EKO05_0009852 DNA helicase K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E EKO05_0003229 DNA topoisomerase K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E EKO05_0009625 uncharacterized protein K15364 NCE4; RecQ-mediated genome instability protein 1
D RPA (replication factor A)
E EKO05_0000568 Replication factor A protein 1 K07466 RFA1; replication factor A1
E EKO05_0001517 Replication factor A protein 2 K10739 RFA2; replication factor A2
E EKO05_0007608 uncharacterized protein K10740 RPA3; replication factor A3
D Protein phosphatase 4
E EKO05_0011236 Platinum sensitivity protein K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E EKO05_0006270 Structural maintenance of chromosomes protein 5 K22803 SMC5; structural maintenance of chromosomes protein 5
E EKO05_0009620 RNA helicase K22804 SMC6; structural maintenance of chromosomes protein 6
E EKO05_0004632 uncharacterized protein K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E EKO05_0010590 uncharacterized protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E EKO05_0011505 uncharacterized protein K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E EKO05_0001716 26S proteasome complex subunit K10881 SHFM1; 26 proteasome complex subunit DSS1
E EKO05_0003758 uncharacterized protein K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
E EKO05_0010045 Slx4p interacting protein K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E EKO05_0005822 uncharacterized protein K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E EKO05_0006194 Esa1p-associated factor K11339 MORF4L1; mortality factor 4-like protein 1
E EKO05_0009431 uncharacterized protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E EKO05_0002041 uncharacterized protein K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
E EKO05_0002127 DNA helicase K14635 MPH1; ATP-dependent DNA helicase MPH1 [EC:5.6.2.4]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E EKO05_0011440 ATP-dependent DNA helicase II subunit 1 K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E EKO05_0003357 ATP-dependent DNA helicase yku80 K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
D MRX complex
E EKO05_0001401 meiotic recombination K10865 MRE11; double-strand break repair protein MRE11
E EKO05_0003639 DNA repair protein rad50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E EKO05_0007846 DNA ligase (ATP) K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E EKO05_0010155 DNA ligase (ATP) K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
E EKO05_0011353 DNA-directed DNA polymerase K10981 POL4; DNA polymerase IV [EC:2.7.7.7]
E EKO05_0001709 DNA-directed DNA polymerase K10981 POL4; DNA polymerase IV [EC:2.7.7.7]
D Other NHEJ factors
E EKO05_0005527 uncharacterized protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E EKO05_0003734 uncharacterized protein K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
E EKO05_0006241 MHF histone-fold complex component K11511 APITD1; centromere protein S
D Bloom's syndrome complex (BTR)
E EKO05_0009852 DNA helicase K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E EKO05_0003229 DNA topoisomerase K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E EKO05_0009625 uncharacterized protein K15364 NCE4; RecQ-mediated genome instability protein 1
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
E EKO05_0001928 Phosphodiesterase I K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E EKO05_0001365 RecA recombinase Rhp51 K04482 RAD51; DNA repair protein RAD51
E EKO05_0002063 telomere binding protein K11137 TELO2; telomere length regulation protein
E EKO05_0001542 uncharacterized protein K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
E EKO05_0001540 uncharacterized protein K23314 WRAP53; telomerase Cajal body protein 1
E EKO05_0002977 uncharacterized protein K24752 WDR70; WD repeat-containing protein 70
E EKO05_0000621 uncharacterized protein K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D EKO05_0001198 DNA-directed DNA polymerase K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D EKO05_0006188 DNA-directed DNA polymerase K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D EKO05_0004144 DNA-directed DNA polymerase K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D EKO05_0001019 deoxycytidyl transferase K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D EKO05_0004404 DNA-directed DNA polymerase K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D EKO05_0005762 E2 ubiquitin-conjugating enzyme K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D EKO05_0009314 RING-type E3 ubiquitin transferase K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D EKO05_0005297 DNA helicase rad5 K15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]
D EKO05_0008210 RING-type E3 ubiquitin transferase K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D EKO05_0001594 E2 ubiquitin-conjugating protein mms2 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D EKO05_0006498 E2 ubiquitin-conjugating enzyme K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D EKO05_0001863 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D EKO05_0009544 uncharacterized protein K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D EKO05_0005134 Exodeoxyribonuclease III K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D EKO05_0008753 Checkpoint protein hus1 K10903 HUS1; HUS1 checkpoint protein
D EKO05_0003811 Exodeoxyribonuclease III K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D EKO05_0002093 RFC checkpoint protein Rad17 K06662 HRAD17; cell cycle checkpoint protein
D EKO05_0008604 replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D EKO05_0001940 Subunit of heteropentameric Replication factor C (RF-C) K10755 RFC2_4; replication factor C subunit 2/4
D EKO05_0002854 Subunit of heteropentameric Replication factor C (RF-C) K10756 RFC3_5; replication factor C subunit 3/5
D EKO05_0006307 Replication factor C (RF-C) subunit K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D EKO05_0003811 Exodeoxyribonuclease III K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D EKO05_0004823 Topoisomerase 1-associated factor 1 K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D EKO05_0004810 chromosome segregation in meiosis-protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D EKO05_0005624 uncharacterized protein K11272 MRC1; mediator of replication checkpoint protein 1
C Triple T complex
D EKO05_0002063 telomere binding protein K11137 TELO2; telomere length regulation protein
D EKO05_0011520 uncharacterized protein K20403 TTI1; TELO2-interacting protein 1
C BAG6-UBL4A-GET4 complex
D EKO05_0002949 uncharacterized protein K23388 UBL4; ubiquitin-like protein 4
D EKO05_0003173 uncharacterized protein K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D EKO05_0004835 Non-specific serine/threonine protein kinase K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D EKO05_0005209 Non-specific serine/threonine protein kinase K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D EKO05_0007208 Non-specific serine/threonine protein kinase K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D EKO05_0008103 Non-specific serine/threonine protein kinase K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D EKO05_0000571 Protein-tyrosine-phosphatase K02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
D EKO05_0003576 14-3-3 protein K06630 YWHAE; 14-3-3 protein epsilon
D EKO05_0008348 uncharacterized protein K06630 YWHAE; 14-3-3 protein epsilon
D EKO05_0000498 Non-specific serine/threonine protein kinase K03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
D EKO05_0003452 transcription factor, variant 2 K24664 FKH; forkhead protein FKH
D EKO05_0009670 Vacuolar protein sorting-associated protein 4 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D EKO05_0006368 uncharacterized protein K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D EKO05_0000572 DNA-directed DNA polymerase K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
C Nucleases
D EKO05_0001875 DNA cross-link repair protein PSO2/SNM1 K15340 DCLRE1A; DNA cross-link repair 1A protein
D EKO05_0000477 uncharacterized protein K17815 EXO5; exonuclease V [EC:3.1.-.-]
D EKO05_0002743 uncharacterized protein K05986 NUCS; nuclease S1 [EC:3.1.30.1]
D EKO05_0003648 uncharacterized protein K05986 NUCS; nuclease S1 [EC:3.1.30.1]
C Helicases
D EKO05_0002521 uncharacterized protein K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
C PSO4 complex
D EKO05_0005534 RING-type E3 ubiquitin transferase K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D EKO05_0001507 Pre-mRNA-splicing factor cef1 K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D EKO05_0010287 uncharacterized protein K12861 BCAS2; pre-mRNA-splicing factor SPF27
D EKO05_0001770 pre-mRNA-splicing factor prp46 K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D EKO05_0011172 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EKO05_0001861 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D EKO05_0007520 Ribonucleoside-diphosphate reductase K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D EKO05_0005452 Ribonucleoside-diphosphate reductase K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D EKO05_0004162 Methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D EKO05_0004572 Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D EKO05_0002622 Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E EKO05_0009513 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E EKO05_0007244 DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E EKO05_0000870 uncharacterized protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E EKO05_0001375 uncharacterized protein K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E EKO05_0007632 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E EKO05_0000847 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E EKO05_0004046 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E EKO05_0004046 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D EKO05_0011172 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EKO05_0001861 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024