+C Two-component system KO
#
Two-Component System - Burkholderia sp. HB1
%
!
AOmpR family
B PhoR-PhoB (phosphate starvation response)
C AC233_12770 histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C AC233_12775 chemotaxis protein CheY K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
C AC233_31870 histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C AC233_16395 histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C AC233_27505 histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C AC233_07735 histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C AC233_04235 histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C AC233_16365 ompR; osmolarity response regulator K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
C AC233_07740 chemotaxis protein CheY K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
C AC233_04230 ompR; osmolarity response regulator K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
C AC233_16390 ompR; osmolarity response regulator K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
C AC233_31875 ompR; osmolarity response regulator K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
C AC233_27510 transcriptional regulator K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
B RstB-RstA
B CpxA-CpxR (envelope stress response)
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
C AC233_21605 histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C AC233_23480 histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C AC233_04970 histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C AC233_21600 transcriptional regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C AC233_23485 transcriptional regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C AC233_04965 transcriptional regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
B QseC-QseB (quorum sensing)
C AC233_31380 histidine kinase K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C AC233_31695 histidine kinase K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C AC233_33730 histidine kinase K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C AC233_33735 regulator K07666 qseB; two-component system, OmpR family, response regulator QseB
C AC233_31385 regulator K07666 qseB; two-component system, OmpR family, response regulator QseB
C AC233_31700 regulator K07666 qseB; two-component system, OmpR family, response regulator QseB
B KdpD-KdpE (potassium transport)
C AC233_05210 sensor protein KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C AC233_05215 Fis family transcriptional regulator K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
C AC233_21535 histidine kinase K07649 tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
C AC233_27180 histidine kinase K07649 tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
C AC233_21540 transcriptional regulator K07774 tctD; two-component system, OmpR family, response regulator TctD
C AC233_21820 transcriptional regulator K07774 tctD; two-component system, OmpR family, response regulator TctD
C AC233_27175 transcriptional regulator K07774 tctD; two-component system, OmpR family, response regulator TctD
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
C AC233_27750 histidine kinase K14981 chvI; two-component system, OmpR family, response regulator ChvI
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C AC233_14830 histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C AC233_14980 transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
C AC233_28240 chemotaxis protein CheY K02483 K02483; two-component system, OmpR family, response regulator
C AC233_14835 XRE family transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
C AC233_20220 chemotaxis protein CheY K02483 K02483; two-component system, OmpR family, response regulator
C AC233_28170 transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
C AC233_17775 transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
C AC233_31230 histidine kinase K07673 narX; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3]
C AC233_22835 histidine kinase K07673 narX; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3]
C AC233_31225 XRE family transcriptional regulator K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL
C AC233_22830 XRE family transcriptional regulator K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL
C AC233_28650 LuxR family transcriptional regulator K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
C AC233_22205 histidine kinase K07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
C AC233_25955 histidine kinase K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]
C AC233_01925 LuxR family transcriptional regulator K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB
C AC233_01935 LuxR family transcriptional regulator K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB
C AC233_16885 LuxR family transcriptional regulator K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB
C AC233_01930 LuxR family transcriptional regulator K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB
B BarA-UvrY (central carbon metabolism)
C AC233_22200 LuxR family transcriptional regulator K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
C AC233_01945 histidine kinase K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
C AC233_25700 chemotaxis protein CheY K07690 evgA; two-component system, NarL family, response regulator EvgA
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
C AC233_28655 histidine kinase K02480 K02480; two-component system, NarL family, sensor kinase [EC:2.7.13.3]
#
ASpo family
B KinABCDE-Spo0FA (sporulation control)
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
#
ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
C AC233_11865 histidine kinase K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
C AC233_11860 chemotaxis protein CheY K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
B NtrY-NtrX (nitrogen regulation)
C AC233_00510 histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
C AC233_00515 XRE family transcriptional regulator K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
B HydH-HydG (metal tolerance)
C AC233_12990 Fis family transcriptional regulator K07713 zraR; two-component system, NtrC family, response regulator HydG
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
C AC233_06620 histidine kinase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C AC233_01440 ATPase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C AC233_01445 Fis family transcriptional regulator K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
C AC233_06625 Fis family transcriptional regulator K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
C AC233_20050 histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C AC233_20040 histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
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ACheA family
B CheA-CheYBV (chemotaxis)
C AC233_17385 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C AC233_17350 chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C AC233_17390 chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C AC233_31275 hypothetical protein K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C AC233_17355 chemotaxis protein K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C AC233_04730 hypothetical protein K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C AC233_20505 chemotaxis protein CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C AC233_10570 hypothetical protein K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C AC233_04720 chemotaxis protein CheR K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61]
C AC233_05875 chemotaxis protein CheV K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
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ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
C AC233_27625 chemotaxis protein CheY K10916 cqsS; two-component system, CAI-1 autoinducer sensor kinase/phosphatase CqsS [EC:2.7.13.3 3.1.3.-]
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
C AC233_21235 histidine kinase K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3]
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
C AC233_00640 histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
C AC233_00645 chemotaxis protein CheY K15012 regA; two-component system, response regulator RegA
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
C AC233_09235 chemotaxis protein CheY K19622 phcR; two-component system, response regulator PhcR
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C AC233_30535 histidine kinase K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3]
B PdtaS-PdtaR
C AC233_33880 response regulator receiver protein K22010 pdtaR; two-component system, response regulator PdtaR
B NasS-NasT
C AC233_21530 nitrate ABC transporter substrate-binding protein K22067 nasS; two-component system, oxyanion-binding sensor
C AC233_21525 histidine kinase K07183 nasT; two-component system, response regulator / RNA-binding antiterminator
B Unclassified
C AC233_27575 histidine kinase K20971 ladS; two-component system, sensor histidine kinase LadS
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023