+E Replication protein KO
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DNA Replication Proteins - Cryptococcus gattii
%
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
D CGB_E4480W replication control protein 1 K02603 ORC1; origin recognition complex subunit 1
D CGB_K2710W DNA replication origin binding protein K02604 ORC2; origin recognition complex subunit 2
D CGB_M2470C origin recognition complex subunit 4 K02606 ORC4; origin recognition complex subunit 4
D CGB_B3410W hypothetical protein K02607 ORC5; origin recognition complex subunit 5
D CGB_D8220C DNA clamp loader K02213 CDC6; cell division control protein 6
D CGB_D8280C DNA clamp loader K02213 CDC6; cell division control protein 6
D CGB_G3410C DNA replication licensing factor cdc19 (cell division control protein 19) K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D CGB_B1120C ATP dependent DNA helicase K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D CGB_M2450C DNA unwinding-related protein K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
D CGB_A0440W ATP dependent DNA helicase K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
D CGB_A1490W DNA unwinding-related protein K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
D CGB_F4520C ATP dependent DNA helicase K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
C CDK (cyclin dependent kinase)
C DDK (Dbf-4 dependent kinase)
D CGB_A6630C hypothetical protein K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
D CGB_N2350W DNA repair protein Rad35 K02309 DBF4; regulatory subunit for Cdc7p protein kinase
C GINS complex
D CGB_G3680C hypothetical protein K10732 GINS1; GINS complex subunit 1
D CGB_C7300C hypothetical protein K10733 GINS2; GINS complex subunit 2
D CGB_D8420W hypothetical protein K10734 GINS3; GINS complex subunit 3
D CGB_G3530C hypothetical protein K10735 GINS4; GINS complex subunit 4
C Other initiation factors
D CGB_B6100W hypothetical protein K03507 DPB11; DNA replication regulator DPB11
D CGB_E2005W cell division control protein 45 K06628 CDC45; cell division control protein 45
D CGB_F0530W hypothetical protein K10736 MCM10; minichromosome maintenance protein 10
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
D CGB_F1120W DNA polymerase alpha catalytic subunit K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
D CGB_M2020C alpha DNA polymerase K02321 POLA2; DNA polymerase alpha subunit B
D CGB_E2210W DNA primase small subunit K02684 PRI1; DNA primase small subunit [EC:2.7.7.102]
D CGB_I2380C DNA primase large subunit (DNA primase 58 kDa subunit) (p58) K02685 PRI2; DNA primase large subunit
C DNA polymerase epsilon complex
D CGB_K2570C DNA polymerase epsilon, catalytic subunit A K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
D CGB_F1400C epsilon DNA polymerase K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
D CGB_G1400W DNA polymerase epsilon p12 subunit (dna polymerase epsilon subunit 4) K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
C DNA polymerase delta complex
D CGB_K3720C delta DNA polymerase K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
D CGB_B8190W DNA polymerase delta, small subunit K02328 POLD2; DNA polymerase delta subunit 2
D CGB_C9570W hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
D CGB_L3530C hypothetical protein K03505 POLD4; DNA polymerase delta subunit 4
C DNA polymerase gamma complex (mitochondrial)
D CGB_B9410C gamma DNA-directed DNA polymerase K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
C RPA (replication protein A)
D CGB_D5240W damaged DNA binding protein K07466 RFA1; replication factor A1
D CGB_D7370C hypothetical protein K10739 RFA2; replication factor A2
D CGB_A3320C single-stranded DNA binding protein 12k chain K10740 RPA3; replication factor A3
C RFC (replication factor C)
D CGB_K2700C DNA replication activator 1 subunit1 (Replication factor C subunit 1) K10754 RFC1; replication factor C subunit 1
D CGB_G3360C subunit of heteropentameric Replication factor C (RF-C); Rfc3p K10755 RFC2_4; replication factor C subunit 2/4
D CGB_L0470C DNA replication factor (activator 1 subunit) K10755 RFC2_4; replication factor C subunit 2/4
D CGB_N0500W DNA replication factor K10756 RFC3_5; replication factor C subunit 3/5
D CGB_A1550C subunit of DNA Replication factor C (RF-C); Rfc5p K10756 RFC3_5; replication factor C subunit 3/5
C RNase H
D CGB_B4060C ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D CGB_H3530C ribonuclease HI large subunit K10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
D CGB_H4050C hypothetical protein K10744 RNASEH2B; ribonuclease H2 subunit B
C Other elongation factors
D CGB_M1090C DNA processivity factor; Pol30p K04802 PCNA; proliferating cell nuclear antigen
D CGB_E5260C DNA replication helicase dna2 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D CGB_H1530W DNA helicase K19783 HCS1; DNA polymerase alpha-associated DNA helicase A [EC:5.6.2.3]
D CGB_D3420W flap endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D CGB_B9610W exonuclease K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
D CGB_H3700W DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DNA Replication Termination Factors
C DNA methylation enzymes
C Prevention of re-replication factors
C Telomere proteins
D Shelterin complex
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
D CST complex (yeast)
D RIF proteins
D SIR proteins
E CGB_B3740C member of the Sir2 family of NAD(+)-dependent protein deacetylases; Hst3p K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
E CGB_J0520C histone deacetylase K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
C Telomerase complex (animals)
D CGB_E2760C telomeric template RNA reverse transcriptase K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Dyskerin complex
E CGB_H4070C small nucleolar RNP protein K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
E CGB_E2280C nucleolar protein family A member 2 K11129 NHP2; H/ACA ribonucleoprotein complex subunit 2
E CGB_D4200W hypothetical protein K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
E CGB_D5480W centromere/microtubule binding protein cbf5 K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
C Telomerase complex (fungi)
D CGB_E2760C telomeric template RNA reverse transcriptase K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Sm core complex
E CGB_I3560W hypothetical protein K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E CGB_B9500W pre-mRNA splicing factor K11087 SNRPD1; small nuclear ribonucleoprotein D1
E CGB_A3310W pre-mRNA splicing factor K11096 SNRPD2; small nuclear ribonucleoprotein D2
E CGB_A0460W pre-mRNA splicing factor K11088 SNRPD3; small nuclear ribonucleoprotein D3
E CGB_H5330W small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E CGB_D5780C mRNA processing-related protein K11098 SNRPF; small nuclear ribonucleoprotein F
E CGB_J0080C hypothetical protein K11099 SNRPG; small nuclear ribonucleoprotein G
C ELG1-RFC complex
D CGB_G3360C subunit of heteropentameric Replication factor C (RF-C); Rfc3p K10755 RFC2_4; replication factor C subunit 2/4
D CGB_L0470C DNA replication factor (activator 1 subunit) K10755 RFC2_4; replication factor C subunit 2/4
D CGB_N0500W DNA replication factor K10756 RFC3_5; replication factor C subunit 3/5
D CGB_A1550C subunit of DNA Replication factor C (RF-C); Rfc5p K10756 RFC3_5; replication factor C subunit 3/5
C MRN complex
D CGB_E0670W meiotic DNA double-strand break processing-related protein K10865 MRE11; double-strand break repair protein MRE11
D CGB_N1500W DNA repair protein Rad50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
C Other termination factors
D CGB_F3720C telomere length control protein K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D CGB_C6500C ATP-dependent DNA helicase hus2/rqh1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D CGB_L2190W single-stranded DNA endonuclease; Rad1p K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D CGB_M1530C hypothetical protein K11135 PINX1; Pin2-interacting protein X1
D CGB_H3330W telomeric DNA binding protein K11137 TELO2; telomere length regulation protein
D CGB_L3150W DNA helicase involved in rDNA replication and Ty1 transposition; Rrm3p K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D CGB_C4290W DNA repair and recombination protein pif1, mitochondrial precursor K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D CGB_J1610W guanyl nucleotide binding protein K23314 WRAP53; telomerase Cajal body protein 1
D CGB_F1170C hypothetical protein K25059 SDE2; replication stress response regulator SDE2
D CGB_D2150W hypothetical protein K25186 RTF2; replication termination factor 2
B DNA Topoisomerases
C CGB_H4710W topoisomerase I K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C CGB_B4210C DNA topoisomerase II K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C CGB_D9400W DNA topoisomerase type I K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
D RNase H
E CGB_B4060C ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D Other elongation factors
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E CGB_B4060C ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
E CGB_E5260C DNA replication helicase dna2 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
E CGB_D3420W flap endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E CGB_H3700W DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
C Prevention of re-replication factors
B DNA Topoisomerases
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022